When treating hypertensive patients with high systolic blood pressure, we should also pay attention to diastolic blood pressure. In the past clinical trials of HEP, it has been proved that active blood pressure reduction can significantly reduce cardiovascular disease (CVD) in hypertensive patients with simple high systolic blood pressure. The purpose of this paper is to study the relationship between CVD and DBP reduction. After adjusting factors such as age, sex, previous medication, smoking, previous heart disease history, stroke or diabetes, it was found that SBP in the control group decreased by 5 mmHg, CVD decreased by 4%, and DBP remained unchanged. In the treatment group, SBP decreased by 5 mmHg and CVD decreased by 7%. If DBP decreases by 5 mmHg, CVD will increase by 10%. When SBP reaches the standard, CVD decreases by 29%, and if DBP falls below 55 mmHg, CVD increases by 99%. Therefore, in the treatment of patients with simple high systolic blood pressure, attention should be paid to keeping DBP not less than 55 mmHg. Circulation1998; Abnormal triglyceride reaction occurred after 98: 862 hypertensive fat meal. After the fat meal of coronary heart disease (CAD), the reaction of serum triglyceride (TG) increase is strengthened and prolonged. However, it is not clear how hypertensive patients react to fat meals. In this paper, 15 hypertensive patients without coronary heart disease, 15 normotensive patients without coronary heart disease and 15 normotensive patients with coronary heart disease were studied. The content of fat meal is: 83.5% fat, 1604 calories /m2 body surface area. TC, TG and HDL were measured at 6 hours and 8 hours after fat meal. It was found that there was no change in TC and HDL after meal in each group, and the TG of patients with hypertension and coronary heart disease at 6 hours after meal was significantly higher than that of the control group (hypertension group was 270±96mg%% coronary heart disease group was 257150 mg%, and control group was 65 438 060 75 mg%, P < 0.00 16,