1, antitussive, expectorant and antiasthmatic effects: mice were given Pyrrosia Lushan 10 1 (decoction concentrated solution), 4 10, 4 1 1, 1A, and. Judging from the ratio of lethal dose to effective antitussive dose in mice, 4 10 with lethal dose of10 has obvious antitussive effect, and its titer is higher than that of the original crude drug and other components. Oral administration of 4 10, intraperitoneal injection of 4 10, 41,4 1 1-c, 1A have obvious expectorant effect (phenol red Dogs with tracheal bags take 4 10 daily for 3 or 6 weeks, and the amount of sputum in tracheal bags has no obvious change, but it can be reduced when it is used to treat chronic tracheitis in clinic, probably because there is no chronic inflammation and no pathological increase in sputum in tracheal bags. However, all the extracts have no obvious antiasthmatic effect (guinea pig histamine spray method).

2. Therapeutic effect on chronic bronchitis in rats: After the chronic bronchitis is stimulated by sulfur dioxide, it is taken orally for 465,438+00 and 65,438+00 days every day, for two courses of treatment. The volume of serous glands and mucinous acinus in the treatment group was smaller than that in the control group, and the goblet cells in large and small bronchi were less than that in the control group, especially in bronchioles. This is consistent with the phenomenon of sputum reduction after clinical medication. In addition, the inflammation and epithelial cell lesions in the treatment group are also lighter than those in the control group, which may be related to the decrease of mucus secretion and accumulation in the bronchus and the improvement of local and systemic conditions. Whether Lushan Mountain of Shiwei itself has nonspecific anti-inflammatory effect needs further study.

3. Pyrrosia decoction has different degrees of inhibition on Staphylococcus aureus, Proteus, Escherichia coli and so on. Has antiviral, antitussive and expectorant effects.