Why does the knee joint hurt? There are many reasons for knee pain, such as trauma, degeneration, inflammation, rheumatic immune diseases and so on. But the most common reasons are the destruction of articular cartilage and abnormal proliferation of bone (spur), which leads to uneven articular surface and friction during activities, thus causing pain, swelling, joint deformity and even noise.
The role of glucosamine glucosamine is a derivative of glucose, and there is no sugar after conversion. At present, glucosamine sulfate and glucosamine hydrochloride are common, and there is no difference in effect.
1. Glucosamine is an important component of cartilage, so it can not only repair damaged cartilage, but also strengthen the structure of cartilage. Keep its elasticity and toughness and slow down its strain.
2. Glucosamine is also involved in the formation of joint fluid, which plays a role in lubricating and nourishing articular cartilage. Reduce friction.
3. Glucosamine has a strong anti-inflammatory effect, which can obviously relieve the pain symptoms of joints.
How to eat ammonia candy? As for the dosage of glucosamine, the dosage produced by each manufacturer is different and the usage is different. However, we recommend not to exceed 2000 mg per day. Too much is not easy to absorb, and it is easy to produce adverse reactions.
As for the process of glucosamine, it takes at least one month. You can take it orally for three months and then stop taking it for a while. Many patients say that they don't care after eating, and some just can't stick to oral administration.
Glucosamine also has some side effects, such as abdominal pain, diarrhea, nausea and vomiting. Symptoms of dizziness, lethargy and even insomnia. Some of them are allergic. But overall, there are few side effects.
Calcium tablets Calcium is an indispensable element for human body and an important part of bones. Appropriate calcium supplementation can not only enhance bone strength, but also prevent osteoporosis. It can also play an important physiological role in hemostasis and sedation.
Glucosamine has a good effect on the knee joint, of course, some people may not have a good effect. It cannot be suitable for everyone. Others say that the effect is not good, one is that the expectation is too high, and the other is that the knee joint continues to be damaged, which will accelerate if it is not aggravated. I hope these can help everyone.
Articular cartilage has no innervation and no vascular nutrition, so this metabolic renewal cycle is longer. The nutrition of cartilage mainly depends on the extrusion of joint fluid and the supply of branches around joint capsule. The components of cartilage include collagen fibers, proteoglycans and scattered chondrocytes (maintaining cartilage metabolism).
Glucosamine is not a sugar that people think (natural amino monosaccharide, so diabetics can eat it), but a chondroprotective agent. Oral amino sugar can promote the synthesis of proteoglycan and hyaluronic acid, improve the metabolism of articular cartilage, thus improving the ability of cartilage repair and relieving joint pain.
It is reported that amino sugar can stimulate the production of articular fluid, increase the nutrition of articular cartilage and reduce wear. In addition, amino sugar can inhibit the activity of some degrading enzymes, thus alleviating pain and delaying the progress of osteoarthritis to some extent.
Aminoglycan has a certain effect on early and middle osteoarthritis. There are some Move Free in the choice of amino sugar cartilage supplement: blue bottle? Red bottle? Green bottle? Patients often ask this question. In terms of choice, mild pain can choose routine. The pain is severe, you can choose to add MSM. Suffering from osteoporosis, you can choose to contain vitamin D.
The effect of amino sugar on knee joint is controversial. Whether amino sugar has curative effect on knee joint diseases has been controversial. No medicine can cure all diseases, and amino sugar is no exception. For friends with bad knees, everyone's illness may be different, and the therapeutic effect of using the same medicine-ammonia sugar is different naturally.
The main function of amino sugar is to promote cartilage repair and regeneration. Some patients with knee pain and discomfort are due to cartilage degeneration, some are joint instability, meniscus injury and so on. Therefore, only those cases of cartilage injury and degeneration can effectively use amino sugar, and cannot be generalized.
There are two kinds of amino sugars in the market: glucosamine hydrochloride and glucosamine sulfate. Studies have shown that the therapeutic effect of the latter is due to the former, and what's more, glucosamine hydrochloride is almost ineffective, so I suggest you buy glucosamine sulfate, which is more reliable.
How should I eat ammonia candy? In order to give full play to the therapeutic effect of drugs, many manufacturers make glucosamine calcium tablets into compound preparations-glucosamine calcium tablets, which I personally do not support. In fact, simple preparation can play the best therapeutic effect.
Aminoglycan is a slow-acting and long-lasting drug, so it takes a long time to take it, at least 1 month to see the curative effect. For some patients, it feels ineffective if they don't insist on taking it, which may be caused by insufficient time to take it. Aminopolysaccharide has little side effects and can be taken for a long time. What is the maximum amount of amino sugar to eat every day? It is recommended not to exceed 2000mg, or take the medicine under the guidance of a doctor or pharmacist.
Osteoarthritis refers to a group of heterogeneous diseases with joint symptoms and signs, which are mainly caused by the integrity destruction of articular cartilage and the pathological changes of subchondral bone plate and joint edge, that is, the degeneration of articular cartilage and secondary hyperosteogeny.
Traditional treatments for osteoarthritis are painkillers and non-steroidal anti-inflammatory drugs. However, recent studies have shown that non-steroidal drugs will aggravate the degeneration of bone and joint. Collagen synthesis and mucopolysaccharide in articular cartilage are blocked, which leads to water retention, swelling, softening and fragmentation of cartilage, excessive growth of bone at the edge of joint and formation of osteophyte, which limits joint activity. With the progress of the disease, the degradation and destruction of articular cartilage matrix increase and the synthesis decreases, leading to joint pain and functional loss.
Glucosamine is a kind of amino monosaccharide synthesized by human body, and it is the main component of glycosaminoglycan, proteoglycan and hyaluronic acid in cartilage matrix and synovial fluid. It is generally believed that glucosamine protects articular cartilage by affecting the synthesis and degradation rate of chondroproteoglycan. Arthritis is related to the dysfunction of glucosamine synthesis in cartilage. Studies have shown that exogenous glucosamine can stimulate cartilage to synthesize more proteoglycans and mucopolysaccharides, while inhibiting the degradation of cartilage by collagenase and phospholipase. By blocking the pathogenesis of joint degeneration, glucosamine can relieve joint symptoms and delay the progress of the disease, even after stopping using it for several weeks. High dose glucosamine showed slight anti-inflammatory effect in animal models. The results of clinical trials show that glucosamine can not only improve the symptoms of bone and joint, but also control the disease.
At the same time, some studies show that glucosamine has the same or even better efficacy as non-steroidal anti-inflammatory drugs in clinical trials of bone and joint treatment. Vitamin D and calcium should be supplemented appropriately while taking glucosamine.
This question feels like consulting elderly parents, so I want to say it first. If I guess wrong, please forgive my sense of smell as a doctor.
Knee joint pain in the elderly goes to the hospital, and the most common is osteoarthritis (OA) of the knee joint in the elderly. For the drug treatment of OA, general analgesics to control symptoms, such as acetaminophen and other NSAIDs, have both analgesic and anti-inflammatory effects.
Then there are drugs and chondroprotective agents to improve the condition, such as glucosamine and chondroitin sulfate A. The glucosamine calcium tablets you want to ask are glucosamine, which can improve the metabolism of articular cartilage, relieve the pain symptoms of OA and improve joint function. It can be used as a treatment choice for OA in the early and middle stages, but it is ineffective for patients with end-stage osteoarthritis with severe articular cartilage wear.
In addition, some studies have shown that glucosamine and chondroitin sulfate have similar efficacy to placebo, so their position in OA treatment needs further understanding.
What are the benefits of taking glucosamine calcium tablets to maintain joint health? The glucosamine calcium tablets on the market generally indicate "health food" on the goods, which can be seen. So I personally don't think we should be superstitious about health care drugs.
Personal opinion, for reference only. If you are offended, you can ask me to delete the post.
I am not a doctor. Let me introduce my experience of taking aminoglycoside chondroitin from the perspective of a patient.
This happened two years ago. I live in my daughter's house in Beijing. For a while, I felt pain in my right leg and knee. Sometimes I suddenly feel pain. Somehow, I was worried about the lesion on my leg and decided to go to the hospital to see a doctor. Fortunately, I found the phone number of the orthopedic director of Peking Union Medical College Hospital online. After arriving at the hospital, I communicated with the doctor about my illness. The old doctor asked me to do two tests first, one was to take an X-ray of my knee, and the other was to do a bone mineral density examination. After I came to see the results the next morning, I made an appointment with the old director the next afternoon. The results came out. The director concluded that this is normal pain caused by senile bone degeneration, and I basically don't need treatment. Be careful when you go back. I consulted a doctor. What medicine can I take to relieve it? He said that you can take "aminoglycoside chondroitin", which is a self-funded medicine. It is suggested that I take it for 3 months, which will have certain effect; That's when I started taking glucosamine chondroitin. After taking it for 3 months according to the doctor's advice, the leg pain basically disappeared. Now that my leg doesn't hurt, I won't eat it. However, according to doctors, it is beneficial to protect bone health for elderly people of our age to supplement glucosamine chondroitin at regular intervals.
Knee pain before eating, shoulder blade pain, and sometimes wake up in the middle of the night. Occasionally chat with colleagues until the shoulder blade hurts. Colleagues recommend this glucosamine chondroitin calcium tablet. I bought it with the idea of having a try. I ate two tablets half an hour after dinner and slept very well that night. When I got up in the morning, I thought about it. Why didn't my shoulder blades hurt when I slept last night? That's the process. I used to take calcium tablets, but it didn't work for me. Now I insist on eating once a day after meals, and my knees and shoulder blades are less painful. This is the picture. You can try it.
(1) Benefits of taking calcium glucosamine tablets to keep the knee healthy. If it is caused by degenerative factors of knee arthritis alone, calcium aminoglycoside tablets can be considered, which can be combined with indomethacin in a gentle way to reduce the damage of cartilage and soft tissue of knee joint. ※.
(2) It can also be combined with China acupuncture and physiotherapy hot compress (plaster for eliminating dampness and cold, promoting blood circulation and removing blood stasis). Usually pay attention to going upstairs and downstairs. In the cold winter, please pay attention to cold and warm measures to prevent the illness from getting worse. I hope it helps you. Thank you for your reference.
What benefits does ammonia sugar have for keeping knee joint healthy? In patients with early knee osteoarthritis, doctors will recommend taking glucosamine for treatment. There are also some middle-aged and elderly people who use ammonia sugar to prevent knee osteoarthritis. Many people are using amino sugar, but little is known about what amino sugar is and why it can treat knee osteoarthritis.
Glucosamine is used to treat osteoarthritis because glucosamine is a component of articular cartilage and synovial fluid.
For middle-aged and elderly people, the biggest enemy of knee joint health is knee osteoarthritis, with a very high incidence. According to the estimation of the World Health Organization, 9.6% of men and 18% of women over the age of 60 suffer from symptomatic knee osteoarthritis, of which about13 may develop into disability, which shows the great harm of knee osteoarthritis.
Articular cartilage is the starting point of knee osteoarthritis. Articular cartilage is a layer of transparent cartilage covering the joint surface. In the process of joint movement, the precise interaction between articular cartilage and surrounding tissues minimizes joint wear, and at the same time has the functions of cushioning impact and absorbing energy, so articular cartilage is equivalent to a "protective pad" in the joint.
However, articular cartilage is not indestructible. After working for many years, it will gradually be damaged by wear and tear, and it will also affect subchondral bone and synovium. Subarticular bone will directly rub because it loses the protection of articular cartilage, leading to bone hyperplasia. Synovium is stimulated by cartilage fragments and other free bodies, which will produce chronic inflammatory reaction. This is knee osteoarthritis.
Cartilage degeneration is the root cause of cartilage injury;
Coupled with endocrine, exercise, weight, posture and other factors, articular cartilage will gradually be damaged, from losing luster and smoothness, to a small area similar to skin ulcer, to a large area of cartilage defect, or even complete loss of cartilage, resulting in different degrees of knee osteoarthritis.
Glucosamine is used to treat knee osteoarthritis because glucosamine is an important component of glycosaminoglycan and hyaluronic acid, and it is also a necessary component to synthesize proteoglycan in articular cartilage matrix. Studies have shown that at the age of 30, amino sugar is gradually lost and no longer produced. At the age of 45, the amino sugar in human body is only 18% of that of teenagers, and even less after 60 years old.
At this time, exogenous glucosamine can replace endogenous articular cartilage nutrients, improve cartilage metabolism, improve cartilage self-repair ability and protect damaged cartilage, thus delaying the development of osteoarthritis. At the same time, aminoglycosides also have certain anti-inflammatory effects. Although it is not as effective as non-steroidal anti-inflammatory drugs, it is safer and can relieve pain for patients with mild symptoms.
What are the benefits of calcium tablets for keeping knee joint healthy? What is the relationship between knee joint health and calcium supplementation?
Calcium is a very important component of human body, and it is an indispensable component in various physiological functions and metabolic processes of human body. The most well-known function of calcium is to participate in the composition of bones and teeth. The most well-known hazard of calcium deficiency is osteoporosis.
Just as articular cartilage degenerates with age, so does calcium in bones. Over time, osteoporosis will come quietly. The reasons for this situation are complicated, including the decline of calcium absorption ability of middle-aged and elderly people, as well as the endocrine changes, decreased activity and muscle loss of middle-aged and elderly people.
Once osteoporosis is caused by calcium deficiency, it can also accelerate the occurrence of osteoarthritis, especially the weight-bearing joints such as knee joint. The reasons may include the following two aspects:
Therefore, for middle-aged and elderly people, it is also necessary to ensure adequate calcium to prevent knee osteoarthritis. Typical features of osteoarthritis include hyperosteogeny, and some patients begin to worry whether calcium supplementation will aggravate osteophyte formation. In fact, hyperosteogeny is a compensatory reaction after joint instability and a self-repair process of the body, which is not directly related to calcium deficiency. Therefore, calcium intake should not be specifically restricted to treat osteoarthritis.
Regarding calcium supplementation, young people have a strong ability to absorb calcium and can get enough calcium in their daily diet. Common foods are milk and dairy products, soybeans and bean products, shrimp skin, seaweed, kelp and so on. For middle-aged and elderly people, if they can't get enough calcium from food, they should consider using calcium supplements, and it is best to choose appropriate calcium products and appropriate usage and dosage under the guidance of doctors.
Do you have knee osteoarthritis, so you need to supplement glucosamine calcium tablets? The answer is of course not, but it is not a complete denial. The specific reasons are as follows.
First, it is not necessary to use ammonia sugar, because the treatment of knee osteoarthritis with ammonia sugar is controversial.
The efficacy of glucosamine has always been controversial, both in the guide and in the feedback of folk use, there are opinions for and against it. Let's take a look at the opinions of the major guides:
In foreign countries, amino sugar is a very popular health food, but the main guidelines generally do not recommend it for patients with symptomatic knee osteoarthritis, and of course there is no clear objection. At home, there is such a * * knowledge about the use of ammonia sugar:
Therefore, we can see that not all patients with knee osteoarthritis can benefit from amino sugar, and whether it is effective depends on personal circumstances. You can't follow the trend and you can't generalize. Compared with acetaminophen and non-steroidal anti-inflammatory drugs, the safety of amino sugar is well guaranteed, and patients with early knee osteoarthritis can still try to use it.
Second, calcium tablets are not necessarily used, because osteoporosis is not necessarily calcium deficiency.
What we usually call calcium deficiency refers to dietary calcium deficiency, that is, calcium is not eaten enough. Osteoporosis patients, bone calcium deficiency is affirmative, but it doesn't mean dietary calcium deficiency.
Calcium-containing food is digested and absorbed in the intestine after entering the human body, and then converted between blood calcium and bone calcium, which is also affected by many factors. Such as vitamin D, sex hormone, thyroid hormone, parathyroid hormone, calcitonin, glucocorticoid and so on. Will affect bone reconstruction. Therefore, even if enough calcium is obtained from food, osteoporosis will still occur if it cannot be absorbed and if bone absorption is greater than bone formation in bone reconstruction.
Therefore, patients with osteoporosis should not only ensure adequate dietary calcium, but also ensure adequate vitamin D. They can get more sunshine every day, and they can also choose vitamin D supplements under the guidance of doctors. For postmenopausal women with osteoporosis, estrogen supplementation should be considered, and patients with thyroid diseases should actively treat the primary disease in order to effectively treat osteoporosis.
The incidence of bone and joint diseases in China is very high, with 60% in people over 55 years old and over 80% in people over 60 years old. Almost all people aged 60 and over have different degrees of joint diseases.
Most people with poor joints are actually familiar with drugs such as glucosamine calcium tablets. When I go out to the clinic, I am often asked by patients: "The joints are not good. Is it good to eat glucosamine calcium tablets? " I will give you an answer today.
What exactly is ammonia sugar? In fact, glucosamine is a kind of glucosamine, and it is also an essential monosaccharide substance for human body. Usually, it is rich in human articular cartilage and is an essential nutrient element for cartilage tissue.
Can taking ammonia sugar repair joints? As the saying goes, "suit the right medicine." Whether taking ammonia sugar can repair joints depends on three aspects:
In daily life, there are many reasons for joint pain. If joint degeneration, such as knee joint degeneration, is not too serious, ammonia sugar has a certain auxiliary effect on early lesions.
For middle-aged and elderly people, if there is occasional slight pain in the easily worn parts such as cervical vertebra, elbow joint, knee joint, lumbar vertebra, wrist and ankle joint, you can take ammonia sugar appropriately, which also has a certain auxiliary effect.
However, if the articular cartilage is seriously worn or even disappears, ammonia sugar may not be effective. It is best for patients to go to a regular hospital as soon as possible to find a professional doctor for treatment.
What should I pay attention to when taking ammonia sugar? 1. Don't rush for success.
Although amino sugar has the effect of preventing osteoarthritis, the content of this drug is relatively small, and patients need to take it for a long time, and the effect will be more obvious. Many patients found that joint problems had not changed significantly after taking it for a few days, so they thought it was ineffective and gave up taking it halfway. This is absolutely inappropriate.
2. Diabetic patients should use it with caution.
If you have diabetes, try not to take such drugs privately, because diabetic patients should pay attention to the control of blood sugar, and ammonia sugar contains a certain amount of sugar. Once taken, it is likely to lead to an increase in blood sugar, which is not conducive to the stability of the disease.
3. Eat less high-fat food.
During taking amino sugar, eat less high-fat food to avoid the stimulation of high-fat food on joints.