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What prescription is used to treat different symptoms of acute glomerulonephritis?
Acute glomerulonephritis (hereinafter referred to as "acute glomerulonephritis") is a diffuse proliferative damage of glomerular capillaries caused by immune response, mostly caused by streptococcal infection or other bacteria, viruses and parasites. It is common in school-age children and adolescents, with more males than females. It is characterized by acute onset, hematuria, proteinuria, edema and hypertension, and may be accompanied by transient azotemia. Most of this disease has a good prognosis.

Acute nephritis generally belongs to the category of edema (yang water) and hematuria in traditional Chinese medicine. Its pathogenesis, mostly due to exogenous pathogenic factors, lung can not pass, water can not pass, wind inhibits water resistance, overflow the skin and cause edema; Dampness and heat accumulate in bladder, burn blood collaterals and cause hematuria; Proteinuria due to spleen deficiency and kidney qi deficiency. The disease site is lung, spleen and kidney, involving bladder meridian and triple energizer. According to the syndrome differentiation and classification, the methods of dispersing lung and promoting diuresis, cooling blood and stopping bleeding, clearing away heat and toxic materials, strengthening spleen and promoting diuresis, and fixing astringency and essence were adopted respectively.

Fangyi Cao Kun Maogen Decoction (Zhong Xinyuan)

Source: Records of Famous Doctors' Prescriptions, Fourth Series

Comprises cogongrass rhizome, oldenlandia diffusa, motherwort and plantain each 30g.

Function of clearing away heat and toxic materials, promoting blood circulation and promoting diuresis.

Indications: Acute glomerulonephritis.

Fang Maojie's rhizome can "dispel blood stasis, dissipate stagnation, collect cold and heat, and facilitate urination", with motherwort as the main ingredient, plantain as the auxiliary ingredient, and Hedyotis diffusa as the heat-clearing and detoxicating agent. The combination of the four medicines, combining sweet and cold taste with bitter taste, makes the qi-moving agile and dynamic without hurting healthy qi, and plays the role of clearing away the source and eliminating evil spirits.

Pharmacology cogongrass rhizome can relieve renal vasospasm, increase renal filtration and produce diuretic effect. Hedyotis diffusa can stimulate the proliferation of reticuloendothelial system, promote the formation of antibodies, and enhance the phagocytosis of reticulocytes and leukocytes, thus achieving the purpose of antibacterial and anti-inflammatory. Motherwort can improve renal microcirculation and cell membrane permeability, thus eliminating edema and proteinuria. Plantago asiatica has antibacterial, anti-inflammatory, diuretic and lower serum creatinine level.

Usage: decoct above twice, concentrate the decoctions to about 150ml, and take them on an empty stomach for three times, twice a day and at night 1 time.

Fangerxuan Fei Jing Watermark (Zhang Zhijian)

Source: Records of Famous Doctors' Prescriptions, Fourth Series

It consists of Herba Schizonepetae10g, Fructus Forsythiae10g, Bombyx Batryticatus10g, Periostracum Cicadae10g, Radix Astragali10g, Radix Saposhnikoviae10g and Atractylodis Rhizoma10g.

It has the effects of dispersing lung qi, expelling pathogenic wind, strengthening body resistance, and clearing away the source.

Indications: acute nephritis. Symptoms include persistent proteinuria, repeated colds, sore throat, facial edema, thin tongue coating, thin or floating pulse.

The prescription uses Schizonepeta tenuifolia, Forsythia suspensa, Bombyx Batryticatus, and Cicadas cicadae to disperse lung and dispel wind, disperse stagnation and break up aggregation, activate coke to drive away evil spirits, disperse lung and regulate qi, and purify water sources; Pyrrosia helps the essence of lung and kidney, and the upper and lower parts intersect, making the waterway small and convenient. Zhong Fang Yuhe Feng Ping Powder aims at invigorating qi, strengthening body and regulating immune function. Adding Glycyrrhrizae Radix and Endothelium Corneum Gigeriae Galli, concocting drugs, invigorating spleen and promoting transport; Rehmannia glutinosa is used to nourish kidney yin and assist Xia Yuan. The whole prescription has the functions of dispersing lung qi and expelling wind, strengthening body resistance and eliminating evil, clearing away the source and purifying water.

Pharmacology Schizonepeta tenuifolia, Saposhnikovia divaricata and cicada slough have inhibitory effects on streptococcus. Forsythia suspensa has inhibitory effects on pathogenic microorganisms such as Staphylococcus aureus, hemolytic streptococcus, Shigella dysenteriae, influenza virus and rhinovirus, and also has anti-inflammatory and diuretic effects. Pyrrosia has antihistamine and diuretic effects. Astragalus can enhance immune function, relieve glomerular vasospasm, increase renal blood flow and filtration rate.

Usage: daily 1 dose, 400 ml for the first decoction and 400 ml for the second decoction, twice in the morning and evening, after meals 1 hour. After the symptoms are relieved and the curative effect is achieved, you can take 1 dose every other day, or grind the above dose into pills, take it twice in the morning and evening, and take 6 ~ 9g each after meals to consolidate, and stop taking the medicine for 3 months after the urine protein disappears continuously.

Fangsan Shufeng Lishui Decoction (Zou Yunxiang)

Source "Essence of Contemporary Famous Doctors in China"

It consists of Flos Lonicerae, Fructus Forsythiae, Poria, Radix Scrophulariae, Herba Dendrobii, Liuyi Powder (6 parts of talc, 0/part of licorice/kloc, and * * * uniformly ground and mixed), Coicis Semen 1 2g, 30g of Rhizoma Phragmitis, 3g of peach kernel and 3g of safflower.

Function of dispelling wind and clearing heat, harmonizing collaterals and permeating benefits.

Indications: acute nephritis. Symptoms include eyelid edema, listlessness, thirst and rapid pulse.

Honeysuckle and forsythia in the prescription can dispel wind and clear heat; Peach kernel, safflower and blood stasis; Coicis Semen, Poria cocos, Liuyi Powder and Rhizoma Phragmitis are permeable to dampness and diuresis; Scrophularia and Dendrobium nobile nourish yin and produce body fluid. The combination of all kinds of medicines can dispel wind and clear heat, harmonize collaterals and ooze benefits.

Pharmacology honeysuckle, forsythia, etc. can clear away heat and detoxify, improve immune function, resist allergic inflammation, improve blood circulation of kidney, promote the repair of pathological damage of kidney and absorb fibrin. Porphyrin is similar to aldosterone and its antagonist in structure, and its diuretic and hygroscopic effects are also related to its mechanism of affecting water and salt regulation in vivo. Reed rhizome has inhibitory effect on hemolytic streptococcus. Peach kernel and safflower dilate blood vessels and improve renal blood circulation.

Usage: daily 1 dose, decocted in water and taken separately.

Fang Si Fang Hua Li Qing Tang

Source: hebei journal of traditional chinese medicine Magazine.

Comprises 30g of oldenlandia diffusa, 30g of forsythia suspensa15g, 0g of scutellaria baicalensis Georgi10g, 0g of cicada slough10g, 20g of burdock, 0g of Eupatorium odoratum10g, 20g of atractylodes rhizome, 30g of coix seed, 30g of lalang grass rhizome, 30g of motherwort and 30g of gentian rhizome.

Function of clearing heat and promoting diuresis, expelling wind and detoxicating.

Indications: Acute glomerulonephritis with damp-heat syndrome.

Hedyotis diffusa, Forsythia suspensa, Scutellaria baicalensis Georgi, Periostracum Cicadae and Fructus Arctii in the prescription clear away heat and toxic materials, disperse lung and promote qi, and cover lung to control the whole body's qi. When it is gasified, it becomes wet. Eupatorium odoratum, Coicis Semen, Rhizoma Atractylodis and Rhizoma Smilacis Glabrae are beneficial to damp-heat and spleen strengthening; Motherwort, cogongrass rhizome and Achyranthes bidentata promote blood circulation, promote diuresis and benefit kidney; Pericarpium Citri Tangerinae is fragrant, invigorating spleen and benefiting qi. The whole prescription has the functions of clearing away heat and promoting diuresis, expelling wind and detoxicating, dispersing blood and gathering qi.

Pharmacological and pharmacological studies have confirmed that Hedyotis diffusa and other traditional Chinese medicines for clearing away heat and toxic materials have the functions of removing antigens, inhibiting antibodies, inhibiting the production of immunocompetent cells and inhibiting the release of allergic mediators. Hedyotis diffusa can also stimulate the proliferation of reticuloendothelial system and enhance the function of phagocytes. Burdock can clear urine protein and inhibit the damage of immune complex formation to kidney; Motherwort, Achyranthes bidentata and other drugs for promoting blood circulation and removing blood stasis have the functions of increasing renal blood flow, improving microcirculation, regulating immune function and resisting free radical damage.

Usage: decoction, daily 1 dose.

Fangji Guisu Chanbaizhu Decoction

Source: Henan Traditional Chinese Medicine

Consists of Herba Ephedrae, Ramulus Cinnamomi, Folium Perillae10g, Periostracum Cicadae 6g, Rhizoma Atractylodis Macrocephalae 30g, and 3 slices of ginger.

Solve the problem and benefit the water.

Indications: Acute glomerulonephritis with wind-cold exterior syndrome at first.

Ephedra in the prescription perspires and relieves exterior syndrome; Gui Zhi reconciled the camp and guards; Ventilator with perilla leaves and cicada clothing; Atractylodes macrocephala and ginger strengthen spleen and promote diuresis. All the medicines are combined into one, and * * * plays "open the door of hell and clean the house", proclaiming achievements.

Pharmacology Ephedra dilates renal blood vessels, increases renal blood flow, and prevents renal tubules from reabsorbing sodium ions, thus playing a diuretic role. Guizhi is anti-inflammatory and anti-allergic, and has a certain diuretic effect. Perilla leaf and cicada slough have inhibitory effect on streptococcus. The decoction and fluid extract of Atractylodes macrocephala have obvious and lasting diuretic effects on rats, rabbits and dogs by gavage or intravenous injection.

Usage: decoct in water, take warm, 1 dose, 2 ~ 4 times a day.

Liu Fang Mahuang Forsythia Red Bean Danshen Decoction

Source "journal of traditional chinese medicine, Hubei"

It consists of 4-9g ephedra, 8-15g forsythia suspensa, 0/5-25g adzuki bean, 9-12g mulberry bark, 6-9g bitter almond, 3-6g ginger, 9-15g motherwort and 4 Chinese dates.

Clearing heat and relieving exterior syndrome, promoting blood circulation and promoting diuresis.

Indications: acute glomerulonephritis with exterior syndrome of damp-heat.

In the prescription, ephedra spreads lung, promotes diuresis to reduce swelling, and almond lowers lung qi; Forsythia suspensa can clear away heat and toxic materials, be compatible with Cortex Mori, and clear away lung heat and promote diuresis; Ginger can not only help ephedra to disperse dampness, but also help almonds to lower lung qi. Jujube neutralization, adzuki bean diuresis, the combination of the two drugs can gradually restore spleen and kidney function; Motherwort promotes blood circulation and diuresis; Salvia miltiorrhiza promotes blood circulation and removes blood stasis. The combination of various medicines has the effects of expelling wind, reducing swelling and promoting diuresis.

Pharmacology Modern pharmacological studies have confirmed that ephedra can increase renal blood flow and induce diuresis. Forsythia suspensa has antibacterial, anti-inflammatory and diuretic effects. Mulberry bark has diuretic effect, which can increase the urine volume of animals and the excretion of sodium, potassium and chlorine. Motherwort can improve renal microcirculation and cell membrane permeability, thus eliminating edema and proteinuria. Salvia miltiorrhiza is a powerful oxygen free radical scavenger, and it also has the functions of lowering blood lipid, lowering blood pressure, strengthening heart, anti-inflammatory and bacteriostasis.

Usage: daily 1 dose, decocted in water, taken orally twice in the morning and evening.

Fangqi Qidan Maoling Decoction

Source: Hunan Guide to Traditional Chinese Medicine

It consists of Radix Astragali10-30g, Radix Salviae Miltiorrhizae10-20g, Rhizoma Imperatae 20-60g, Rhizoma Smilacis Glabrae 50-200g, Herba Leonuri 6-20g, Fructus Hordei Germinatus 20-40g, Fructus Arctii 6-10g and Rhizoma Bletillae 6-6544.

Functions: invigorating spleen, diuresis, cooling blood, promoting blood circulation, and detoxicating.

Indications: Acute glomerulonephritis. The exterior syndrome has been eliminated, leaving only edema, proteinuria and hematuria (mostly microscopic hematuria).

Radix Astragali, Rhizoma Smilacis Glabrae and Fructus Hordei Germinatus in the prescription strengthen the spleen and promote diuresis, which accords with the mechanism of "it is in the spleen". Salvia miltiorrhiza, cogongrass rhizome, motherwort and madder are the products of promoting blood circulation and removing blood stasis, and adding Bletilla striata to promote blood circulation and stop bleeding without leaving blood stasis is beneficial to the elimination of hematuria; Fructus Arctii and Herba Houttuyniae have the functions of expelling wind and clearing away heat and toxic materials. Compatibility with drugs for promoting blood circulation and removing blood stasis can prevent chronic toxicity and blood stasis.

Pharmacology According to recent reports, Radix Astragali, Rhizoma Smilacis Glabrae, Herba Houttuyniae, Herba Leonuri and Rhizoma Cynanchi Stauntonii can eliminate proteinuria. Imperata rhizome can relieve glomerular vasospasm, improve renal blood flow, reduce renin production, reduce blood pressure and diuresis, reduce vascular permeability and reduce protein excretion.

Usage: decoction, daily 1 dose.

It is said that our reuse of Smilax glabra stems from Professor Ren Jixue's experience.

Jiawei Fangba Sanren Decoction

Source: Journal of Traditional Chinese Medicine Emergency

Is prepared from almond 15g, cardamom 15g, coix seed 20g, Pinellia ternata 15g, Rhizoma Cyperi 15g, medulla tetrapanacis 10g, talc 15g, bamboo leaves 20g, pyrrosia 30g and lalang grass rhizome.

Function of promoting qi circulation and eliminating damp heat.

Indications: Acute glomerulonephritis.

The almond in the recipe is bitter and warm, good at opening the coke and dispersing lung qi; Cardamom is fragrant and bitter, which can be used to declare medium coke; When used together with Pinellia ternata and Magnolia Officinalis, it can relieve dampness by bitter warming and restore the function of ascending middle energizer and clearing turbidity; Coix lachryma-jobi is sweet and light in taste, beneficial to spleen and dampness, and can dredge lower energizer. It can be mixed with medulla tetrapanacis, talc and bamboo leaves to clear away damp heat. Pyrrosia tastes bitter and cool, clearing lung and nourishing source, dredging bladder and benefiting waterways. Cogongrass rhizome tastes sweet and cold, and can penetrate stagnation heat, conduct heat downwards, clear the supernatant, cool blood and stop bleeding.

Pharmacology Modern pharmacology has proved that coix seed can enhance humoral immunity and promote antibody production. Pyrrosia has antihistamine and diuretic effects. Cogongrass rhizome can relieve glomerular vasospasm, reduce vascular permeability, induce diuresis and eliminate protein. Houpu decoction has inhibitory effect on pneumococcus, hemolytic streptococcus, Shigella dysenteriae and Staphylococcus aureus. Tetrapanacis tetrapanacis can increase the excretion of potassium ions in urine, thus playing a diuretic role.

Usage: decoction, daily 1 dose.

Anti-aging loquat leaf soup

Source: hebei journal of traditional chinese medicine Magazine.

Comprises loquat leaf15-30g, almond12-15g, fried gardenia peel, fermented soybean, medulla tetrapanacis, poria peel 20-30g, talc 25-30g, and coix seed18-30g.

Function: clearing lung, transforming qi, promoting diuresis and reducing swelling.

Indications: Acute glomerulonephritis in children.

Almonds and loquat leaves in the prescription taste bitter, which can make the congested lung qi clear and clear, and make the waterway smooth; Gardenia and Douchi can "declare their stale stagnation" (Wang Meng English), clear away heat and remove turbidity; Poria cocos, coix seed, talc, medulla tetrapanacis, etc. It is light and cool, which makes gasification wet, drowning and swelling.

Pharmacological studies show that loquat leaves and gardenia have antibacterial and anti-inflammatory effects. Tetrapanacis tetrapanacis can increase the excretion of potassium ions in urine and induce diuresis. Porphyrin is similar to aldosterone and its antagonist in structure and regulates water and salt metabolism in vivo. Coix seed enhances immunity.

Usage: daily 1 dose, decocted twice.