1, endocrine disorder. Such as diabetes, hyperthyroidism, Cushing's syndrome, hypogonadism, pituitary prolactin's tumor, hypopituitarism and other diseases. The decrease of sex hormone secretion in middle-aged and elderly people is one of the important causes of osteoporosis.

2. Lifestyle factors. Bad lifestyle, such as frequent sunbathing, staying up late, lack of exercise, etc., will affect bone metabolism and lead to osteoporosis.

3. Drug factors. Long-term use of certain drugs, including adrenal glucocorticoids, anticancer drugs, antiepileptic drugs, etc. , can also cause osteoporosis.

4. Digestion and absorption factors. Such as chronic gastritis, subtotal gastrectomy, chronic pancreatic diseases, chronic liver diseases, malnutrition and other patients, often accompanied by osteoporosis.

5. Genetic factors. Osteoporosis is hereditary.