The English name of protein peptide IGF- 1, also known as human growth factor, is an active protein polypeptide, which is the product of autocrine and paracrine of more than a dozen cells such as liver cells, kidney cells and spleen cells in human body (that is to say, the human body itself contains IGF- 1). Its specific functions are as follows:
1. Hypoglycemic: IGF- 1 Similar to insulin in this respect, it can enhance the absorption of glucose and amino acids, promote the synthesis of glycogen and the secretion of lactic acid, inhibit the decomposition of glycogen, increase the sensitivity of human body to insulin, and improve the efficiency of human insulin. It has a good therapeutic effect on insulin-independent diabetes (type II diabetes).
2. Hypolipidemic: IGF- 1 can promote lipolysis and glycogen synthesis, and reduce the levels of total triglycerides, very low density lipoprotein triglycerides and low density lipoprotein cholesterol in blood. (Literature confirmed that it does not affect lipolysis)
3. Vasodilation: IGF- 1 can regulate the physiological and pathological conditions of the heart, and has the functions of relaxing blood vessels, reducing vascular resistance and increasing cardiac blood flow.
4. Promote bone anabolism and maintain its normal structure and function: IGF- 1 can obviously promote the division and proliferation of chondrocytes from various sources and the synthesis of cartilage matrix. IGF- 1 can also stimulate chondrocytes to synthesize cartilage matrix-specific collagen-type ⅱ, increase the activity of glycosaminoglycan polymerase and enhance the activity of alkaline phosphatase in osteoblasts.
5. Growth promotion: IGF- 1 is a very important mitotic promoter in human body (exactly within a certain concentration range).
6. Promote cell differentiation: IGF- 1 is very important to maintain the protein level related to cell differentiation, and it can promote cell differentiation and maturation when combined with some growth factors.
7. Wound repair: IGF- 1 is also involved in the process of wound healing. Experiments show that the concentration of IGF- 1 in injured nerve, muscle and skin cells increases.