Huangdi Neijing is a comprehensive medical work, which establishes the theories of Yin and Yang, five elements, pulse condition, Tibetan image, meridians, etiology, pathogenesis, symptoms, diagnosis, treatment, health preservation and luck.

Discussing medicine in a holistic view presents a "holistic medical model" of nature, biology, psychology and society (according to the research of modern scholars, it is considered that the traces of Huang family in this edition are invaded by Taoist priests in Sui and Tang Dynasties). Its basic material comes from the long-term observation of life phenomena in ancient China, a lot of clinical practice and simple anatomical knowledge.

The basic theoretical spirit of Huangdi Neijing includes: holistic view, yin and yang, five elements, viscera and meridians, etiology and pathogenesis, diagnosis and treatment, prevention and health preservation, and luck theory.

"Holism" emphasizes that the human body and nature are a whole, and the structure of the human body and its parts are interrelated.

② "Yin-Yang and Five Elements" is a theory to explain the unity of opposites between things.

③ "Zangxiang Jing" mainly studies the physiological functions, pathological changes and their relationships of the five zang-organs, the twelve meridians and Qijing.

④ "Etiology and pathogenesis" expounds whether various pathogenic factors act on human body and the internal mechanism of disease changes.

⑤ "Diagnosis and treatment" is the basic principle for TCM to recognize and treat diseases.