Efficacy of Psoralea corylifolia
Treat vitiligo
Psoralea corylifolia is a commonly used Chinese medicine for treating vitiligo, which contains psoralen. After grinding, it was soaked in 95% alcohol for 5-6 days at the ratio of 30g per100 ml. The filtrate was applied to the affected area and irradiated with sunlight or UVA. The old doctor of traditional Chinese medicine reminds us to pay attention to eye protection, avoid ultraviolet damage, take medicine at night and wear anti-ultraviolet goggles within 24 hours after taking medicine.
Killing effect on leukemia cells
Psoralea corylifolia contains psoralen, which has a strong killing effect on human leukemia cells, and its killing intensity is proportional to the drug concentration. Isopsoralen plus black light irradiation has anti-rejection effect on rabbit skin transplantation.
Estrogen-like effect and anti-implantation
Psoralen can cause estrogen-like changes in ovariectomized female rats, significantly increase the weight of uterus, and has a strong estrogen-like effect. Psoralen and isopsoralen have significant anti-sperm implantation effects in mice, and intrauterine injection of psoralen and isopsoralen in female mice has anti-early pregnancy effects. Experiments have confirmed the ancient understanding that psoralen can abort. Compendium of Materia Medica lists it as? Abortion? Medicine. Is there a record in the Classic of Materia Medica? Can I have an abortion? .
Enhance immunity and increase white blood cells.
It can enhance the immune function of the body and improve the phagocytosis of peritoneal macrophages in mice. It can promote the growth of granulocyte progenitor cells and resist leukopenia caused by cyclophosphamide injection. The mechanism may be that psoralea corylifolia coumarin stimulates adrenal cortex and increases white blood cells.
Have a photosensitive effect
Therefore, skin pigment tyrosinase is the key enzyme in human melanin biosynthesis. Psoralea corylifolia can improve the activity of tyrosinase in human body, promote the synthesis of melanin and restore the skin color of white spots. Achieve the purpose of treating vitiligo.
Expanding crown and strengthening heart to stop bleeding
Psoralen B can obviously dilate coronary artery, enhance myocardial contractility in rats, excite frog heart, and resist heart failure caused by lactic acid, which has a cardiotonic effect. Psoralen A also has the function of crown expansion. Psoralea corylifolia can shorten the bleeding time and reduce the amount of bleeding in mice.
be anticancer
Psoralen has a significant inhibitory effect on S 180, Ehrlich ascites carcinoma and liver cancer H-22. Psoralen and 8- methoxysarin have obvious killing effects on Sl80 ascites cells. Psoralen B and volatile oil have anti-cancer effects.
Increase myocardial nutrient blood flow
Is prepared from Fructus Psoraleae, Herba Cynomorii, Rhizoma Polygonati, Rhizoma Cibotii, Radix Dipsaci, Radix Paeoniae Rubra, etc. , made into decoction and concentrated to 3g (crude drug) /ml. In the experiment, 30 mice 18-22g were used for both sexes. They were randomly divided into control group, group I and group II, with 65438 00 rats in each group. In the drug group, the dose was 1.20 g/kg. The control group was given equal volume of normal saline. 0.4 hour after administration of 65438+, RbCl solution (about 6.6-6.9? 10? Cpm/0. 1ml), the injection was completed within 2 minutes and timed immediately. Inject 0.2-0.3 ml saturated KCl solution for 30 minutes. The animals were killed, the heart was taken out, and measured by LKBr counter, and the uptake rate of 86Rb in myocardium was calculated, indicating the myocardial nutrient blood flow.
The experimental results showed that compound Psoralea corylifolia granules could significantly increase myocardial nutritional blood flow in mice (P
Protective effect of pituitrin on acute myocardial ischemia in mice
Thirty male and female mice with body weight 18-22g were randomly divided into control group, pituitrin group and drug group, with 10 in each group. The control group and pituitary group were given 65438 0 g normal saline. After 2.5 hours of administration, the pituitary group and the administration group were injected with L? Dose of pituitrin per kilogram of body weight.
After 30 minutes, the myocardial nutrient blood flow of mice in each group was measured. The results showed that compound Psoralea corylifolia granules had obvious protective effect on acute myocardial ischemia induced by pituitrin in mice.
Antibiotic action
Psoralea corylifolia seed extract has antibacterial effect on staphylococcus and staphylococcus resistant to penicillin and other antibiotics in vitro. Psoralea corylifolia has a certain effect on mold on Shapiro medium, and tincture has a stronger effect than decoction. The petroleum ether extract of seeds has inhibitory effect on earthworms, so it may have anthelmintic effect.
urogenital system
It is a commonly used medicine for treating impotence and premature ejaculation, and has astringent effect. Treating dysuria caused by nocturnal enuresis, senile asthenia or nocturnal polyuria, enhancing renal function, promoting diuresis and reducing swelling.
Treatment of Psoralea corylifolia
It is used for kidney-yang deficiency with cold limbs, soreness of waist and knees, impotence and nocturnal emission, and is compatible with walnut, Eucommia ulmoides and Cuscuta. For deficiency asthma due to deficiency of kidney-qi, it is often combined with walnut and agarwood. For those with unstable fetal movement due to kidney deficiency, it is equivalent to Eucommia ulmoides, Ejiao and Dangshen.
For patients with spleen and stomach weakness, Fructus Psoraleae120g, Semen Myristicae 60g as fine powder, 49 Chinese dates, and ginger120g can be decocted together, and the ginger is removed and the jujube meat is ground into pills. If you have diarrhea for a long time, you can use it with poppy shell.
Treatment of uterine bleeding: appropriate amount of Psoralea corylifolia. Take Fructus Psoraleae 18g daily and decoct in water. Take it orally two or three times a day. When necessary, the administration time can be appropriately extended.
Treatment of streptomycin poisoning and allergic reaction: Psoralea corylifolia 600g. Take 20g of Psoralea corylifolia every day and put it in 100 ml of water for decoction. Take it twice a day for 7 to 30 days. Mainly suitable for dizziness, unstable standing and walking, even falling, tinnitus and deafness, shaking things.
Treatment of vulvar leukoplakia: appropriate amount of Psoralea corylifolia and equal amount of 95% alcohol. Soak Fructus Psoraleae in alcohol for seven days, filter to obtain liquid medicine, and then boil with steady fire to concentrate, usually to 50 ml per 500 ml of liquid medicine. Before taking the medicine, clean and disinfect the vulva, and then evenly apply the liquid medicine to the affected area once every other day.
Treatment of verruca vulgaris: Psoralea corylifolia 30g, 70% ethanol 100ml. Pulverizing Fructus Psoraleae, soaking in ethanol for seven days, and filtering to obtain liquid medicine. Dip a small amount of Psoralea corylifolia with a matchstick and drop it on the wart several times a day until it is cured.
Treatment of sweat spots: Psoralea corylifolia 40g, 95% alcohol 300ml. Soak Fructus Psoraleae in alcohol until it turns iodine. Apply the liquid medicine to the affected area four to five times a day for two to three days.
Treatment of leukopenia: 500 grams of Psoralea corylifolia, fried and ground into fine powder, added with honey and made into pills, each weighing 6 grams. Take one to three capsules each time, three times a day, with light salt and hot water. Take 3 grams of Psoralea corylifolia powder with light salt water three times a day for one month.
Psoriasis: a single flavor is immersed in 95% alcohol, and the affected area can be wiped with the immersion liquid after one week.
Vitiligo: Eclipta prostrata, Astragalus membranaceus and Sesamum nigrum each 20g, Angelica sinensis, Polygonum Multiflori Radix and Ligustrum lucidum each 65,438 05g, Atractylodes macrocephala and Poria each 65,438 02g, Ligusticum Chuanxiong, Psoralea corylifolia each 65,438 00g, and Glycyrrhiza uralensis 5g. Take one dose of decoction every day for one month as a course of treatment.
Frequent micturition and enuresis: stir-fry a single flavor, grind it into powder and take it orally.
How to eat Psoralea corylifolia
1, Braised Mutton with Psoralea corylifolia
Material: mutton (thin)100g.
Accessories: Psoralea corylifolia 10g, Eucommia ulmoides Oliv. 12g.
Practice: Slice the mutton first, add appropriate amount of water and stew for 30 minutes; Then add Eucommia ulmoides Oliv. and Psoralea corylifolia, and cook for15min; Have soup and mutton.
Efficacy of health care and dietotherapy: enriching blood, strengthening waist, invigorating spleen and benefiting qi; It is suitable for lumbago due to blood deficiency in the elderly.
2. Braised beef tendon with Fructus Psoraleae
Material: beef tendon (foam) 1250g.
Accessories: 50 grams of rapeseed heart and 5 grams of Psoralea corylifolia.
Seasoning: salt 8g, monosodium glutamate 10g, sugar 20g, cooking wine 20g, starch (pea) 20g, peanut oil 30g, pepper 2g, onion 5g and ginger 5g.
Practice: Wash Psoralea corylifolia and put it in a jar, add water and steam it in a cage to get juice. Wash the cabbage, cut the onion into sections and slice the ginger. Beef tendon is cooked with water, cooking wine, onion and ginger to remove its odor. Take 1 aluminum pot, put the grates into a pot, add the soup, beef tendon and psoralea corylifolia juice, stew for 2.5 hours on low heat, take out the grates when cooked, put the cows into a plate, leave the juice in the pot to adjust the taste, thicken them evenly with 40 grams of starch (20 grams of water), and then put them into a plate. Stir-fry the Chinese cabbage and enclose it.
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