Ganoderma lucidum polysaccharide is very sensitive to temperature and is a heat-sensitive substance. Most of them are insoluble in high-concentration alcohol and soluble in hot water. When the temperature rises, it will cause the degradation of Ganoderma lucidum polysaccharide, and the glycosidic bond in the polysaccharide is easy to break, forming multiple Tang monomers, but Tang monomers are inactive. At present, the extraction of Ganoderma lucidum polysaccharide mostly adopts membrane separation method, and the whole process is carried out in a closed system without heating, thus avoiding and alleviating the influence of heat and oxygen on the nutritional components of Ganoderma lucidum polysaccharide.