2. There are differences in the approval number, one is the national medicine quasi-word, and the other is the approval number (import drug registration certificate number).
3. The characters are different. Jinshuibao is powder, fragrant and slightly bitter. Lexus capsule: granular, with special smell and slightly salty taste.
4. Jinshuibao has stipulated inspection standards, but Lexus capsules don't.
5. Different specifications, Jinshuibao has only one specification: 0.33G*63 tablets, and Zhiling Capsule has several specifications: 0.25g*36 tablets, 0.25g*50 tablets, and 0.25g* 12S*2 tablets.
This is all the difference. Use whatever you want! Done! Call it a day! Let's go!
Generic name: Jinshuibao Capsule
Pinyin Name: Jinshuibao Capsule
Page number: 2000 edition 1 -499
This product is a capsule made of fermented Cordyceps powder (Cs-4).
Properties This product is a capsule with yellowish brown to light brown powder. It smells fragrant and tastes slightly bitter.
Administration and dosage: take orally, 3 capsules at a time, 3 times a day; Used for patients with chronic renal insufficiency, 6 capsules at a time, 3 times a day.
Specification: 0.33g per capsule.
Storage seal.
Jinshuibao capsule
Standard source of instructions: Pharmacopoeia 2000 Edition
Approval number: National Medicine Zhunzi Z 10890003[ 1]
Drug name: Jinshuibao Capsule
Function category: This product is an over-the-counter medicine for deficiency syndrome of internal medicine.
Ingredients: Cordyceps powder.
Indications: tonifying lung and kidney and storing qi. It is used for chronic cough and asthma, mental fatigue, insomnia, forgetfulness, soreness of waist and knees, and irregular menstruation caused by deficiency of lung and kidney and deficiency of essence.
Administration and dosage: Take orally, 3 capsules at a time, 3 times a day. For patients with renal insufficiency, take 3-6 capsules orally, 3 times a day.
Edit this paragraph for identification (1) Take the test solution 15ml under 【 Content Determination 】, evaporate it to dryness, and dissolve the residue with 5ml diluted ethanol as the test solution. In addition, adenine reference substance, adenosine reference substance and uridine reference substance were added with dilute ethanol to prepare a mixed solution containing 2mg per kloc-0/ml as reference substance solution. According to the thin-layer chromatography test (appendix ⅵ b), take 65438 00μ l of the test solution and 65438 0μ l of the reference solution, respectively, and spot them on the same silica gel GF254nm thin-layer plate, with 4% sodium carboxymethylcellulose solution as the adhesive, and chloroform-ethyl acetate-isopropanol-water-concentrated ammonia solution (8: 2: 6: 0.3) as the test solution.
(2) Take 65438 0 g of this product, add 65438±00ml of water, heat to boiling, filter, and take the filtrate as the test solution. In addition, leucine reference substance, alanine reference substance and valine reference substance were added together with water to prepare a mixed solution containing 1mg leucine and alanine and 0.5mg valine per 1ml as a reference substance solution. According to the thin-layer chromatography test (Appendix ⅵ b), 3μl of test solution and 2μl of reference solution were respectively spotted on the same silica gel G thin-layer plate with sodium carboxymethyl cellulose as adhesive, and n-butanol-glacial acetic acid-water (4: 1: 1) was used as developing agent, then unfolded, taken out, dried and sprayed with ninhydrin test solution. In the chromatogram of the test sample, spots with the same color appear in the position corresponding to the chromatogram of the control sample.
(3) Take mannitol reference substance and add dilute ethanol to make a solution containing 9mg per kloc-0/ml as reference substance solution. According to the thin-layer chromatography test (Appendix ⅵ b), suck 3μl( 1) of the test solution and 2μl of the above-mentioned reference solution under [Identification], respectively spot them on the same silica gel G thin-layer plate, use isopropanol-ethyl acetate-water (9:6:2) as the developing agent, unfold, take them out, dry them, and spray the anisaldehyde test solution at 654. In the chromatogram of the test sample, spots with the same color appear in the position corresponding to the chromatogram of the control sample.
The inspection shall comply with the relevant provisions under capsules (Appendix Ⅰ L).
Edit this paragraph and determine the content by HPLC (Appendix ⅵ d).
Octadecylsilane bonded silica gel is used as a filler for chromatographic conditions and system suitability test. 2% tetrahydrofuran phosphate buffer solution [0.066mol/L potassium dihydrogen phosphate solution -0.066mol/L disodium hydrogen phosphate solution (4:6)] as mobile phase; The detection wavelength is 260 nm. The theoretical plate number should be not less than 3000 calculated by adenosine peak.
Preparation of reference substance solution Take a proper amount of adenosine reference substance dried under reduced pressure at 105℃ to constant weight, accurately weigh it, and add dilute ethanol to make a solution containing 40μg per 1ml. Preparation of test solution Take the contents of different volumes, mix them evenly, take 65,438 0 g, weigh them accurately, put them in a 50ml volumetric flask, add about 30ml diluted ethanol, perform ultrasonic treatment (power 250W, frequency 33 kHz) for 30 min, let them cool, add diluted ethanol to scale, shake them evenly, let them stand, take the supernatant, and use a microporous membrane (0.45μm).
The determination method accurately absorbs 5μl of the control solution and the test solution, and injects them into the liquid chromatograph for determination.
The content of adenosine (C 10H 13N5O4) in this product should be 0.60 ~ 1.0 mg.
Edit this clinical application 1: treating chronic bronchitis.
According to the experimental results of traditional medicine and pharmacology, we tried to treat chronic bronchitis with deficiency of lung and kidney, deficiency of lung and yin, deficiency of spleen and kidney, and deficiency of kidney yang, including chronic obstructive emphysema, chronic pulmonary heart disease, bronchial asthma, bronchiectasis and obesity with Jinshuibao, and observed the clinical efficacy with the commonly used drugs for treating chronic bronchitis. Results The effective rate of Jinshuibao group was 84.40%. The effective rate of the control group was 42.86%, and the symptoms of chronic cough, night sweats, shortness of breath, cough due to lung deficiency, white and sticky phlegm and less phlegm in Jinshuibao group were obviously improved, and the blood gas analysis and lung function were also improved. The effective time after taking the medicine is about 3 ~ 5 days. It is better to use antibiotics in combination with infection in acute stage. The effect of strengthening the body resistance and treating both the symptoms and root causes is more obvious if you take it alone or take it for 2 ~ 3 months during the remission period.
Second, the treatment of chronic renal insufficiency
Jinshuibao can reduce creatinine and urea nitrogen in patients with chronic renal failure, increase endogenous creatinine clearance rate, lymphocyte transformation rate and mean red blood cell value, and improve hematopoietic and immune functions of patients.
III. Treatment of sexual dysfunction
Jinshuibao capsule has the effects of tonifying kidney, protecting lung and consolidating vital energy. It contains a lot of trace elements such as zinc and selenium, which can comprehensively regulate human body functions, promote gonad development, improve adrenal cortex function, and increase the 24-hour urine excretion of 17- hydroxy and 17- ketone. It has male fistula, premature ejaculation, hyposexuality, irregular menstruation and backache and abdominal pain.
Four: treatment of liver cirrhosis
Cirrhosis is a common, progressive and diffuse liver disease, which is caused by one or several reasons for long-term or recurrent attacks. Histologically, there are extensive degeneration and necrosis of liver cells, nodular regeneration of liver cells, proliferation and fibrosis of connective tissue, which lead to the destruction of normal hepatic lobules, the formation of false lobules, and the gradual deformation and hardening of the liver, which develops into cirrhosis. The main causes of liver cirrhosis are viral hepatitis (mainly hepatitis B), schistosomiasis, alcoholism, cholestasis and circulatory disorders. In the process of liver cirrhosis, connective tissue regeneration and fibrosis play an important role. Experiments have proved that Jinshuibao capsule can alleviate and reverse fibrosis, dredge liver blood flow and enhance immunity, and has a unique effect on the treatment of liver cirrhosis.
Five: reduce blood lipids, prevent atherosclerosis and prevent cardiovascular diseases.
Jinshuibao has the function of inhibiting platelet aggregation and reducing blood viscosity, and has high clinical application value in preventing atherosclerosis, coronary heart disease and cerebral thrombosis. Jinshuibao can also improve dizziness, dizziness, numbness and swelling of limbs, chest pain, chest tightness, fatigue or excessive phlegm caused by hyperlipidemia.
Six: anti-aging, increase SOD activity, repair DNA damage and reduce LPO level.
When people reach middle age, the essence in the kidneys is gradually exhausted, and the functions of the body are gradually reduced, resulting in some senile deficiency syndromes, such as chills, tinnitus, dizziness, loose teeth, frequent nocturia and so on. The aging of human body is an irresistible natural law, but it can play a role in delaying aging by "consolidating the foundation and cultivating the yuan, strengthening the body resistance and tonifying the deficiency" Jinshuibao capsule can tonify kidney and protect lung, store essence and qi, and delay aging.
Seven. Adjuvant therapeutic effect of tumor
Jinshuibao Fuzheng and adjuvant radiotherapy and chemotherapy for advanced lung cancer. At the same time, it was compared with reserpine, sorbitol and other drug-assisted treatment groups. The results showed that the completion rate of radiotherapy/chemotherapy was 95% in Jinshuibao group and 64.65438 0% in control group. The normal rate of hemogram in Jinshuibao group after radiotherapy and chemotherapy was 85%, while that in control group was 58.97%. The tolerance of Jinshuibao group to radiotherapy and chemotherapy was significantly better than that of the control group, and its hemogram inhibition was significantly lower than that of the control group. Experiments show that Jinshuibao can stabilize the hemogram of lung cancer patients, improve the acute decline of white blood cells, hemoglobin and platelets caused by radiotherapy and chemotherapy, enhance the tolerance of lung cancer patients to radiotherapy and chemotherapy, improve immune function, effectively improve spirit, sleep, appetite and lethargy, and reduce the toxic and side effects of radiotherapy and chemotherapy.
Editing this paragraph is mainly used to tonify lung and kidney and secret essence. Can be used for treating deficiency of both lung and kidney, deficiency of essence and qi, chronic cough and asthma, mental fatigue, insomnia and amnesia, soreness of waist and knees, irregular menstruation, impotence and premature ejaculation. Chronic bronchitis, chronic renal insufficiency, hyperlipidemia, liver cirrhosis see the above syndromes.
Edit this paragraph manufacturer Jinshuibao tablets, Jiangxi Jinshuibao Pharmaceutical Co., Ltd. National Medicine Zhunzi Z 109 100 14.
Jinshuibao Capsule Jiangxi Jimin Kexin Jinshuibao Pharmaceutical Co., Ltd. National Medicine Zhunzi Z 10890003
Jinshuibao tablets Jiangxi Jinshuibao Pharmaceutical Co., Ltd. National Medicine Zhunzi Z20003207
Asthma-related drugs: Baihe Gujin Oral Liquid Bailing Capsule Guben Kechuan Tablet Jinshuibao Capsule Kechuanshun Pill Liqidingchuan Pill Maiwei Dihuang Oral Liquid Qingfei Xiaoyan Pill Qutanling Oral Liquid Xiaoqinglong Granule Medical Insurance Related: Jinshuibao Capsule Shanghai 2005 Class B.
Jinshuibao capsule; Limited immune dysfunction, anti-rejection, organ failure and pulmonary fibrosis Liaoning 2005 Grade B.
Jinshuibao Capsule Shaanxi 2005 Grade B
Jinshuibao Capsule Jiangsu 2005 Grade B
The note of this paragraph is 1. Avoid spicy, cold and greasy food.
2. Patients with cold and fever should not take it.
This product should be taken after meals.
People with normal menstruation, sudden menorrhagia or oligomenorrhea, and irregular vaginal bleeding should go to the hospital.
5. Patients with chronic diseases such as hypertension, heart disease, liver disease, diabetes and kidney disease should take it under the guidance of a doctor.
6. It is forbidden for those who are allergic to this product, and should be used with caution for those who are allergic.
7. It is forbidden to use this product when its nature changes.
8. Children must use it under the supervision of adults.
9. Please keep this product out of the reach of children.
10. If you are using other drugs, please consult a doctor or pharmacist before using this product.
1 1. After taking the medicine for 4 weeks, the symptoms have not eased, so I have to go to the hospital.
Pharmacology and Toxicology: Pharmacological experiments show that this product has anti-inflammatory, antitussive, expectorant, sedative and gonadotropic effects: it can reduce serum cholesterol, triglyceride and lipid peroxide, increase blood supply to myocardium and brain, slightly lower blood pressure, inhibit platelet aggregation, prolong the survival time of animals under hypoxia, and protect heart and brain tissues. Its main pharmacological effects are similar to those of natural Cordyceps in Qinghai.
Edit this paragraph. Shuibao capsule is an over-the-counter medicine for internal medicine deficiency syndrome. Nourish lung and kidney, and secret essence. Can be used for treating lung and kidney deficiency, essence deficiency, chronic cough and asthma, mental fatigue, insomnia and amnesia, soreness of waist and knees, irregular menstruation, impotence and premature ejaculation. Its chemical composition is similar to that of natural Cordyceps produced in Qinghai, and it contains adenine nucleoside, uracil nucleoside, mannitol, ergosterol, aspartic acid, glutamic acid, threonine, glycine, lysine, serine, alanine, leucine, proline and other 19 amino acids, zinc, potassium, manganese, phosphorus, selenium and other elements, and vitamin b 1 B2.
Jinshuibao Capsule:
1. Jinshuibao capsule has the greatest side effect on children. If taken temporarily, it will also affect the child's growth and development, as well as sexual function, and also have a certain impact on fertility.
It is possible to get angry, depending on whether your body can make up for it.
This medicine is acidic and should be taken after meals. If it is empty, it may cause gastrointestinal discomfort.
General name of basic information: Lexus capsule
Approval number (registration certificate number of imported drugs): National Medicine Zhunzi Z330202 12.
Description: This product is a brown granule capsule. The smell is special and the taste is slightly salty.
Phonetic name of Lexus capsule: Lexus capsule
This product is a capsule made of Mortierella SP. isolated from Cordyceps sinensis larvae by artificial culture and fermentation.
National traditional Chinese medicine protection variety ZYB20797040- 1+0
Manufacturer: Changxing Pharmaceutical Co., Ltd. [1]
Chinese caterpillar fungus (Berk) SACC is the offspring of ergot plants, the complex of its host moth larvae, and a kind of fungal medicinal materials among precious wild medicinal materials in China. Lingzhi capsule is a fungus isolated from fresh Cordyceps sinensis collected from shrub meadow over 4000 meters in Qinghai-Tibet Plateau. Its mycelium is made by purification, culture and advanced bioengineering technology, which can be comparable to natural cordyceps sinensis, hence the name Lexus capsule. It contains cordycepin, cordyceps polysaccharide, ergosterol, mannitol, 19 kinds of amino acids, and various trace elements such as zinc, manganese, iron and calcium.
Edit the indications, usage and dosage of this paragraph.
Indications: tonifying lung and kidney. Can be used for treating cough, asthma and edema caused by deficiency of both lung and kidney, and can also be used for adjuvant treatment of various nephropathy, chronic bronchial asthma, chronic hepatitis and tumor.
Administration and dosage: Take orally, 2-3 capsules at a time, 2-3 times a day, or as directed by the doctor.
Edit this paragraph pharmacological action pharmacological action research shows that Lexus capsule has the following effects:
● It has the function of tonifying lung and kidney.
● Androgen-like effect: it can improve gonadal function, obviously improve impotence and nocturnal emission caused by the decline of vital energy and qi deficiency, reduce the number of nocturnal emission, eliminate impotence and restore sexual desire. It also has a good effect on primary infertility.
● Improve the cellular immune function of tumor patients undergoing radiotherapy and chemotherapy: improve the delayed allergic reaction of the body, prevent leukopenia of tumor patients during radiotherapy and chemotherapy, and promote leukopenia. Improve patients' weak symptoms such as sleep and food loss, fatigue and sweating.
● Supplementing the deficiency of demand, benefiting kidney and storing essence: It is helpful to the filling of viscera and yin and yang, which is often insufficient, so it has obvious curative effect on chronic renal failure and chronic nephritis. For hypertension and atherosclerosis (coronary atherosclerosis and renal arteriosclerosis), it can improve renal function, blood lipid and urinary protein, and reduce cholesterol. Symptoms such as edema, palpitation, shortness of breath, abdominal distension and oliguria have been significantly improved.
Dilating bronchus: improve immune function by relaxing bronchial smooth muscle. Eliminating phlegm, relieving cough and asthma, so it has good curative effect on expectoration and blood, tuberculosis and chronic bronchitis.
● It has a good curative effect on the syndrome of nervous and endocrine dysfunction in menopausal men and women: symptoms such as fatigue, facial flushing's disease, palpitation and insomnia, dizziness and headache, soreness of waist and legs, edema of face and lower limbs, and decreased libido are obviously improved.
● Effectively inhibit the activity of monoamine oxidase: Because the activity of monoamine oxidase increases with age, it causes biochemical damage to the body and is also one of the reasons for aging. This product can improve the monoamine oxidase system of middle-aged and elderly people, regulate the body function, and at the same time, rich trace elements can improve symptoms such as osteoporosis, decreased intelligence and memory, delay aging and prolong life.
The toxicity test results of the aqueous suspension of this product edited in this paragraph were determined by tube feeding method. The results showed that the maximum oral tolerance was 48g/kg, and the clinical dose was 60kg/d.. The maximum tolerance dose of Lexus capsule is 960 times of the clinical dose of human body, which shows that Lexus capsule has a wide safety range and is basically non-toxic in clinic.
Protected varieties of traditional Chinese medicine are protected by the state. The three manufacturers in China are: Hangzhou Le Kai Pharmaceutical, Zhejiang Changxing Pharmaceutical and Datong Liqun Pharmaceutical.
This paragraph edits the revised opinions of China Pharmacopoeia (20 10 edition).
Pinzhi Mingling Capsule
Source: Issued by the Ministry of Industry and Information Technology 12.
Prescription sketch
The original function is mainly to replenish lung and kidney. Can be used for treating cough, asthma and edema caused by deficiency of both lung and kidney, and can also be used for adjuvant treatment of various nephropathy, chronic bronchial asthma, chronic hepatitis and tumor.
The original usage and dosage are taken orally, 2 ~ 3 capsules at a time, 2 ~ 3 times a day, or as directed by the doctor.
Primitive attention
Main adverse reactions
Primitive taboo
After standardization, the function is mainly to replenish lung and kidney. Can be used for adjuvant treatment of lung and kidney deficiency syndrome of chronic nephropathy and bronchial asthma, as well as chronic hepatitis and tumor.
Standardized usage and dosage are taken orally. Take 2 ~ 3 capsules at a time, 2 ~ 3 times a day, or as directed by the doctor.
Pay attention to the specification.