Taoism prevailed in Wei and Jin Dynasties, and many people studied longevity. Ge Hong, a famous alchemist, summed up the secret of longevity called "Immortal" and wrote the Taoist experience of keeping healthy and living long as "Bao Puzi's Internal and External Articles". Ge Hong's Biography of Immortals records 94 "immortals", all of which are about the longevity experience of the birthday boy over 100 years old. It was widely circulated in the ruling and opposition parties in the Jin Dynasty, and almost a household health book was Huang Tingjing written by Mrs. Wei. According to legend, Mrs. Wei is the daughter of General Emperor Wu of Jin Dynasty. When she was a child, she became a monk and got a true biography from her teacher, so she wrote Huang Tingjing in the form of poetry. After being copied by the calligrapher Wang Xizhi, it is worth a hundred times, especially the wives of folk women and literati. This book is a masterpiece of advanced guidance, and later became a Taoist classic, which played a certain role in popularizing the knowledge of health and longevity. According to legend, an Yi Liren named Wu Dan practiced this advanced guidance and lived to the age of 170. According to Shu Wei, Wang Lie, a native of Handan, once wore Vitex negundo, but he was old and young. Later, he went to Taihang Mountain to practice, and it is said that he lived for more than 300 years. Shu Wei? The Legend of Royer once said: "Royer, passed down from generation to generation, is 107 years old, which is refreshing. ..... In one hundred and ten, a letter to the old man; ..... Every time there is a big event in the imperial court, the post horse asks for an audience and dies at the age of 120. "

Xu Xun, a native of Runan in Jin Dynasty, abandoned his official position to practice medicine. It is said that he lived to the age of 1.36, and his work "Ling Jian Zi" is mainly about health preservation, which has been passed down to this day and is called "Xu Zhenjun".

During the Southern and Northern Dynasties, many centenarians, such as Hui Ke, a famous monk and founder of the second generation of Zen Buddhism, lived to the age of 107 (see Continued Biography of Monks). Just "Southern History"? There are several centenarians in the biography of the imperial clan of Liang, such as "there is a woman named Xia, who is over 100 years old"; Li Zhong-Gu Rensiyuan "120 years old"; The old man in Yucheng is "240 years old, can no longer eat food, but can only drink the milk of his great-grandson"; Bird, a native of Jingzhou, began to be "116 years old, with great brawn and the same diet".