The traditional hangover cure method in China is relatively simple, that is, let the drunk drink a bowl of white vinegar, so that the stomach acid can be greatly increased. 1. Milk hangover method: Drunk people can drink some milk to coagulate protein, protect gastric mucosa and relieve alcohol absorption. 2. Sugarcane juice hangover method: those who are drunk and conscious can chew sugarcane by themselves, and in severe cases, they can squeeze out sugarcane juice to drink and sober up. 3. hangover preserved eggs: when drunk, take 1-2 preserved eggs, take them with vinegar, and sober up.
4. Cabbage hangover method: cut the Chinese cabbage heart into filaments, add sugar and vinegar and mix well. When cold dishes are served on the table, they have a certain effect on eliminating alcohol break.
5. Raw pears for hangover: eat a few pears or peel and slice them, soak them in cold boiled water for 10 minutes, and drink water for hangover. 6. Rice soup hangover method: Drunken people can take thick rice soup, which contains polysaccharide and B vitamins, and has the effect of detoxification and sobering up. Drink with sugar, the curative effect is better.
7. Anti-hangover method of carambola: 1 Carambola is soaked in vinegar and decocted in water, which can be used to sober up. 8. Celery hangover therapy: A proper amount of celery juice can sober up, especially to eliminate symptoms such as headache, brain swelling and facial flushing after drunkenness. 9. Toilet water hangover method: Sprinkle a few drops of toilet water on a hot towel and gently rub the chest, back, elbows and temples of the drunken person, which can obviously reduce their drunkenness.
10. Method of relieving hangover with pestle: After getting drunk, take some fresh pestle, peel it and eat it to sober up.
1 1. Tea for hangover: You can drink strong tea after drunkenness. Tannic acid in tea can alleviate acute alcoholism. Caffeine and theophylline are effective for respiratory depression and drowsiness.
12. Orange juice hangover: dizziness, headache, nausea and vomiting after drinking. You can eat a few oranges or drink fresh orange juice to sober up. 13. Jellyfish hangover relieving method: Take 100g fresh jellyfish, wash it, add water and decoct it, and then sober up.
14. Egg white hangover relieving method: Taking 1-2 raw eggs when drunk can protect the gastric mucosa and reduce the absorption of alcohol. 15. Anti-hangover method of radish: 500 grams of fresh radish is mashed to get juice, taken 1 time, or some raw white radish is eaten in moderation, which can relieve alcoholism.
16. mung bean hangover relieving method: take 50g mung bean, licorice 10g, and add appropriate amount of brown sugar to decoct and sober up. If you only use mung beans to cook soup, it will also have certain effects.
17. hangover syrup: take a proper amount of sugar and take it with boiling water, which has the effect of hangover and refreshing.
18. Vinegar hangover relieving method: Take 50g of rice vinegar or aged vinegar, add 25g of brown sugar and 3 slices of ginger, which can reduce the harm of alcohol to human body.
19. lotus root hangover relieving method: drinking fresh lotus root juice has a certain effect on eliminating drunk symptoms. 20. Sweet potato hangover method: After drunkenness, you can cut raw sweet potatoes into sections, mix in sugar, and hangover.
This directly acts on the liver oxidase system, that is, it activates the physiological activities of ethanol dehydrogenase and acetaldehyde dehydrogenase and promotes the oxidative decomposition of ethanol and acetaldehyde. However, in human body, the digestive system is very unfavorable to ethanol metabolizing enzymes. First of all, the PH value of gastric juice is about 1 ~ 3, and the PH value of intestinal cavity is as high as 6 ~ 7, so the intracellular alcohol dehydrogenase and acetaldehyde dehydrogenase have almost no effect in the stomach. There is almost no acetaldehyde dehydrogenase in gastrointestinal fluid except a small amount of ethanol dehydrogenase. Secondly, the ions in gastric juice (especially bile salts) also inhibit alcohol dehydrogenase and acetaldehyde dehydrogenase. Secondly, the content of NAD+ in gastrointestinal fluid is very small, and the oxidation of ethanol lacks electron acceptor, so it cannot be carried out. Finally, the protease in gastric juice is the natural enemy of other enzymes, and it has been decomposed into amino acids before it can play its role. Therefore, it is limited to taking alcohol dehydrogenase and acetaldehyde dehydrogenase manufactured by biotechnology to relieve alcoholism.
Fourthly, the development of traditional Chinese medicine to protect liver and relieve alcoholism and modern medicine has reached the level of system biology. Transgene and biological reconstruction can be realized, but the principle of traditional Chinese medicine, which has lasted for thousands of years, has not been effectively explained and excavated. Traditional Chinese medicine has its unique advantages and scientific value in modern clinical practice (it plays an irreplaceable role in nourishing and protecting the liver and preventing cancer). However, due to the dual limitations of the unique theoretical system of traditional Chinese medicine and the objective attributes of traditional research methods, a series of scientific problems related to the theory and clinical application of traditional Chinese medicine cannot be effectively solved, which seriously restricts the academic progress and modernization development of traditional Chinese medicine. Metabonomics is an important part of systems biology, and its systematic research ideas are basically similar to the theoretical connotation of the whole concept of traditional Chinese medicine, with the same compatibility. Metabonomics technology is used to analyze the metabolic phenotype of Chinese medicine germplasm resources, and to show the mechanism of action of Chinese medicine and the compatibility law of Chinese medicine prescriptions. The effective collision and reference between traditional Chinese medicine and system biology (metabonomics technology) is an effective attempt to analyze the scientific problems of traditional Chinese medicine and a systematic and in-depth research method following the theoretical connotation of traditional Chinese medicine. Through the systematic collection and analysis of ancient prescriptions for hangover, this paper summarizes the commonly used effective drugs and explores the law of medication and treatment methods. Using statistical software to establish a database, frequency analysis, correlation analysis and cluster analysis were carried out to summarize the law of drug use. After the establishment of the database, frequency analysis showed that Glycyrrhiza uralensis Fisch, Pericarpium Citri Tangerinae, Fructus Hoveniae, Radix Puerariae, Rhizoma Alpiniae Officinalis, Herba Pogostemonis, Flos Lonicerae, Poria, Fructus Amomi, Ginseng and other drugs were the high-frequency drugs of hangover relieving prescription, and they were related. Cluster analysis further pointed out the understanding of drug compatibility in wine prescriptions. Conclusion The law of drug use deduced from statistical data is consistent with the traditional treatment method of "removing dampness from upper and lower parts", which can be applied to the treatment of clinical alcohol-related diseases and the development of traditional Chinese medicine anti-alcoholism preparations.
According to the above analysis method and referring to the national homology catalogue of medicine and food, a group of compatible prescriptions were obtained: Hovenia dulcis Thunb, Radix Puerariae, Radix Glycyrrhizae, Alpinia officinarum, Herba Agastaches, Flos Lonicerae, Lotus Leaf and Stevia rebaudiana. According to metabonomics analysis, these herbs are rich in fructose and vitamins, which can effectively strengthen the metabolic function of the liver, especially peroxidase, which is an oxidoreductase produced by microorganisms or plants and can catalyze many reactions. It can oxidize ethanol and catalyze the decomposition of ethanol acetaldehyde through ethanol dehydrogenase and acetaldehyde dehydrogenase in human body. Based on the analysis of the principle of traditional Chinese medicine, the Hovenia dulcis Thunb was studied. It has the effects of relieving vomiting and hangover, effectively protecting brain, liver and kidney function, and eliminating dizziness, blurred vision and other symptoms. Pueraria lobata: clearing away heat and toxic materials, nourishing the liver and protecting the brain, accelerating the decomposition and excretion of alcohol, and reducing the harm of alcohol to human liver, kidney, spleen, stomach and other tissues. Glycyrrhiza uralensis Fisch: digestion and stomach strengthening, decomposition of alcohol, and elimination of discomfort after drinking. Alpinia officinarum: Warming to stop vomiting, dispelling cold and relieving pain, and being good at hangover can cure headache, dizziness, polydipsia, fullness of chest and diaphragm caused by excessive drinking. Pogostemon cablin: It can relieve vomiting, hangover and bad breath. Honeysuckle: appetizing, detoxifying, and eliminating fire. Lotus leaf and stevia rebaudiana: Both of them have the effects of promoting digestion, sobering up, stopping dizziness, strengthening the spleen and protecting the liver and brain.
This formula has obtained the national invention patent, and the holder is Mr. Zhang Ming, the chairman of Xiangtan Mingfu Health Tea Co., Ltd., who has used it in his company's efficacy tea series Mingfu Health Tea. After a lot of compatibility development and process improvement, combined with the traditional tea-making pharmaceutical principle, the raw materials were made into standardized tea blocks by using modern low-temperature constant-temperature and constant-humidity fermentation technology and ultramicro-cell-broken pharmaceutical technology, which effectively maintained the activity and pharmacological characteristics of the effective components of the raw materials, and 95% of the effective components were fully released during the brewing process. After years of clinical observation, Mingfu Jiejiu Tea has obvious effects of protecting and nourishing the liver, relieving alcoholism and detoxifying.