Through clinical practice, ancient Chinese medicine summarized the incompatibility of traditional Chinese medicine as "eighteen opposites" and "nineteen fears". Traditionally, it was believed that if the opposite drugs were combined, they would enhance or produce toxic and side effects, and should be banned in principle. The full text of the song "Eighteen Contrasts" is: The compendium of materia medica is clear about eighteen opposites, half of which are used to attack Wu, so the kelp is used to mow grass, and the ginseng is all used to fight veratrum. The last sentence "Shenshen Xinshao anti-veratrum", "Shenshen" includes Sophora flavescens, which means that Sophora flavescens should try to avoid veratrum in daily application. The drugs involved in this paper are Pinellia ternata, Trichosanthes kirilowii (including Trichosanthes kirilowii and Trichosanthes), Fritillaria (including Fritillaria thunbergii and Fritillaria cirrhosa), White Drum, Bletilla striata and Radix Aconiti Lateralis (including Radix Aconiti, Radix Aconiti Kusnezoffii, Radix Aconiti Lateralis, Herba Andrographis and Radix Aconiti Lateralis). Seaweed, Euphorbia, Kansui and Daphne genkwa against Glycyrrhiza uralensis Fisch. Ginseng Radix, Radix Codonopsis, Radix Pseudostellariae, Radix Salviae Miltiorrhizae, Radix Scrophulariae, Radix Adenophorae, Radix Sophorae Flavescentis, Asari, Radix Paeoniae Alba and Radix Paeoniae Rubra. The "Nineteen Fears" have traditionally been regarded as the "opposite" compatibility, but now it is generally believed that the "Nineteen Fears" are not absolute compatibility taboos.