1. Historical evolution of taboo and strenuous exercise of rabies vaccine.
In fact, there are many taboos mentioned in the product manual of rabies vaccine. Before China 1980, rabies vaccine was produced from animal brain tissue, with many injections and large doses. In addition, the vaccine at that time was not purified and contained a lot of impurities, so the side effects were great, and drinking and strenuous exercise might aggravate the side effects. Therefore, the vaccine instructions at that time clearly stipulated: "Do not drink alcohol, drink strong tea, eat irritating food, and avoid catching cold or strenuous exercise or labor" (quoted from 60). With the development of technology, the current rabies vaccines are all cell cultured, concentrated and purified, and the adverse reaction rate is greatly reduced. However, Pharmacopoeia 20 15 and some manufacturers' instructions still continue the previous contents, although there is no experimental basis to show that the rabies vaccine currently used should retain the above taboos in diet and exercise.
2. There are no dietary and exercise taboos in rabies vaccines abroad.
Another way to explain this problem is that there is no such taboo in the instructions of rabies vaccines produced abroad (the only taboo mentioned is that "immunosuppressants and antimalarials should be avoided during vaccination"). In the WHO literature on rabies, there has never been any taboo in diet and exercise. So we can think that these taboos on diet and exercise are unnecessary.
3. The reasons for the cultural accumulation in China.
In addition, it is the "common sense" of Chinese medicine to avoid taking medicine, which has been deeply rooted in the hearts of the people. It is generally believed that people should always pay attention to their diet as long as they use drugs. Traditional Chinese medicine is generally absorbed through the digestive tract, and improper diet will affect its absorption and excretion, which is scientifically justified; However, modern biological products are fundamentally different from traditional Chinese medicine in terms of medication mode, pharmacological action and metabolic pathway, so there is no need to pay attention to them in diet.
4. How to treat diet and exercise taboos?
After rabies vaccination, we can observe these dietary and exercise taboos, but we don't have to pay too much attention to them. Drinking strong tea is not good for your health, so it is not only the immune period, but also not drinking at ordinary times. Eating lightly and not exercising vigorously is good for your health. But if we have been drinking, eating hot pot and pepper, or doing strenuous exercise, there is no need to worry. These things will not cause immune failure, and we can live a normal life after vaccination.