Clopidogrel: a new generation of antiplatelet drugs, developed by Sanofi Saint-Drabourg pharmaceutical company in France. By blocking ADP receptor, platelet aggregation function is inhibited and the incidence of cardiovascular and cerebrovascular diseases is reduced. But it also has side effects such as easy bleeding.
Jie Schoepp (GM- 1): It is an imported drug for repairing neuropathy and nerve injury, which is produced by Argentine TRB Pharmaceutical Company. Its active ingredient is monosialotetrahexose ganglioside (abbreviated as GM 1), which is mainly used to treat central nervous system diseases, including brain trauma, spinal cord injury, cerebrovascular accident (stroke), Parkinson's disease and so on. But the price is expensive, injection 100mg× 1 vial/box, 1 132 yuan.
China commonly used traditional Chinese medicine are:
Xinnaojing tablet: the methods of calming the heart and calming the nerves, lowering blood pressure and dredging collaterals, clearing heat and resolving phlegm were adopted. The main components are calculus bovis, Borneolum Syntheticum, Prunellae Spica, Uncaria rhynchophylla, Rhizoma Arisaematis and Herba Gentianae. Can be used for preventing and treating apoplexy, lowering blood pressure, clearing away heart fire, strengthening brain, dredging collaterals, calming nerves, and treating apoplexy.
Zhongfengshen Liquid: produced by Tonghua Tianma Pharmaceutical Co., Ltd., with Herba Siegesbeckiae and stevioside as main ingredients, is mainly used to treat headache and dizziness caused by cerebral thrombosis, cerebral infarction, hemiplegia, weakness of waist and knees, hypertension, hyperlipidemia and stroke.
Xiaoshuan Tongluo tablets: produced by Tianjin Hongfu Pharmaceutical Factory, Mudanjiang Huichun Pharmaceutical Co., Ltd., Guangzhou Xiangxue Pharmaceutical Co., Ltd. and Guangxi Banzhou Pharmaceutical (Group) Co., Ltd.. Comprises Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, Radix Astragali, Rhizoma Alismatis, Radix Notoginseng, Flos Sophorae Immaturus, Ramulus Cinnamomi, Radix Curcumae, Radix Aucklandiae, Borneolum Syntheticum and Fructus Crataegi. Promoting blood circulation and removing blood stasis, warming meridians and dredging collaterals. Can be used for treating apoplexy sequelae (cerebral thrombosis).
Huatuo Zaizao Pill: produced by Guangzhou Qixing Pharmaceutical Co., Ltd., consisting of Chuanxiong, Evodia rutaecarpa, Borneolum Syntheticum, etc. It can selectively block calcium channels in brain cells and their synaptosomes, remove a large number of free radicals produced by damaged brain tissues, regulate the contents of nitric oxide and endothelin in diseased parts of brain tissues and blood, increase the synthesis of nerve growth factor and fibroblast growth factor in brain tissues, protect the functional morphology and organelle integrity of brain cells during ischemia, reduce programmed death (apoptosis) of brain cells, and help to restore and enhance the functions of brain cells. Huatuo Zaizao Pill has the function of protecting, repairing and activating brain nerve cells.
Traditional Chinese medicine (TCM) drugs for stroke are mostly multi-drugs, and there is no clear site of action. The main drugs are promoting blood circulation and removing blood stasis, relaxing muscles and activating collaterals, etc. And the curative effect is not obvious, so it can not be used to treat acute ischemic stroke.