With the development of medicine in China, thousands of medical scientists have appeared in the past two thousand years, among which 100 is the most outstanding, making outstanding contributions. Sun Simiao was a famous physician in the Tang Dynasty, the representative and leader of the most outstanding contributors. If we rank their influence on medical development, Sun Shi is one of the top three. This book is one of a series of books describing the civilization of Han and Tang Dynasties, and it is the research result of Professor Zhang Shiying, a researcher at Sun Simiao Institute, in the past 30 years. This paper introduces Sun Simiao's life, great contribution, cultural origin, the secret of Sun Simiao's health and longevity, Wang Yao, etc. Rich in content, outstanding in characteristics, reflecting history, covering a wide range and being clear at a glance, it is suitable for the needs of both researchers and ordinary readers.