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How to treat brain atrophy?
How to treat brain atrophy? Difference between brain atrophy and head CT examination of Alzheimer's disease

Move your fingers as much as possible. Eat more fresh vegetables and fruits rich in vitamins, walnuts and egg yolks (except those with high cholesterol).

, has the effect of enhancing brain memory. Eat less aluminum-containing food, smoke less and drink less.

All patients with Alzheimer's disease have severe brain atrophy, but elderly people with brain atrophy do not necessarily have Alzheimer's disease, and the two cannot be classified.

size

The human brain consists of brain, diencephalon, cerebellum and brain stem, in which the surface of the brain is covered with sulcus and convex gyrus. here

It is the center of higher spiritual activities, such as language, thinking and memory, and calculation.

With the increase of age, nerve cells can age and die, and the weight of the brain becomes lighter. If you do CT or MRI scan, you can find the brain.

Shrinking volume, widening sulcus, thinning gyrus and expanding ventricles are brain atrophy. Brain atrophy is a normal phenomenon in the process of physiological aging.

Phenomenon, according to the general law, the higher the age, the more obvious the degree of atrophy. Under normal circumstances, brain atrophy will naturally terminate after a certain degree, usually

Under the circumstances, it will not affect daily work and life. And severe atrophy, dementia will occur.

Alzheimer's disease is a problem in which parts of the brain related to memory function (such as hippocampus) are damaged, which will lead to some abnormal phenomena, such as

Memory function is seriously declining, and simple calculation ability is lost in daily life. I have no idea what just happened. If I leave my job, I will forget it.

Remember, eat again; Some people will be accompanied by some symptoms of mental disorders, and later they will lose their ability to take care of themselves.

Brain atrophy caused by cerebral infarction;

Both brain atrophy and cerebral infarction are caused by arteriosclerosis and thrombosis. Due to long-term hypoxia and ischemia of the brain, tissues and cells degenerate and even shrink. cerebrum

What medicine does infarction and brain atrophy take? What is the specific medicine ... is an urgent problem for many patients with cerebral infarction and brain atrophy. but

I must declare here that the treatment of brain atrophy and cerebral infarction must be based on the root cause, not to mention taking one.

Two drugs can cure the disease. In order to completely treat cerebral infarction caused by brain atrophy, it must be systematically standardized.

In the theory of traditional Chinese medicine, cerebral infarction is caused by clearing away qi and stagnation of ventricle, so the method of ascending clearing away qi and descending turbidity should be adopted. Brain atrophy is a kind of traditional Chinese medicine

Deficiency of kidney essence and brain substance can be cured by tonifying kidney.

Cerebral infarction is due to the imbalance of blood and vascular environment, and the contents of triglyceride, cholesterol and low density lipoprotein in blood increase.

The density lipoprotein content decreases, and blood waste is deposited on the blood vessel wall. Over time, blood vessels become brittle and narrow, and blood flow is slow, leading to blood vessels.

Ischemia and hypoxia in the blood supply area will damage brain cells, make the scalp, hands and feet numb, and at the same time get no blood supply, which will appear over time.

Brain atrophy.

In this case, it is necessary to start from two aspects. First, take medicine to regulate, mainly to achieve thrombolysis and thrombosis, purify the vascular environment and dredge the blood.

In addition to the function of blood waste, it can also balance the contents of triglycerides, cholesterol, low density lipoprotein and high density lipoprotein in blood, making blood healthy.

After that, the blood vessels become soft and the numbness naturally disappears.

While taking medicine, we should also pay attention to diet, mainly light, less greasy, avoid spicy food, drink plenty of water, quit smoking and drinking, and transport in moderation.

move

Treatment:

To improve cerebral blood circulation, you can take Weinaolutong and compound Danshen injection. Proper exercise can improve cerebral circulation, but

Coma patients should stay in bed, strengthen nursing, mainly use drugs to dilate cerebral vessels and nourish brain cells. If the disease continues to recur,

In severe cases, it will lead to epilepsy and Alzheimer's disease.

It is suggested to use drugs that nourish brain cells, such as cerebrolysin, cytidine diphosphate choline and Naofukang. Vitamin B complex, inosine tablets, etc. Quit smoking and drinking. avoid

Eat foods containing alum, such as fried dough sticks, and add drugs for symptomatic treatment, such as drugs to control mental symptoms. If there are complications such as lung infection,

Need simultaneous anti-inflammatory treatment.

encephalatrophy

It is suggested to use drugs that nourish brain cells, such as "cerebrolysin", cytidine diphosphate choline, Naofukang, vitamin B complex and inosine tablets. And give up smoking and alcohol. Avoid eating alcoholic food.

Fried dough sticks and other alum foods, plus drugs to control mental symptoms and other symptomatic drugs. If there are complications such as lung infection, the same is needed.

Anti-inflammatory treatment

Shengnaosu soft capsule

Brain growth factor is rich in GM 1, up to more than 92%, which is beneficial to the recovery of brain injury.

Gastrodia elata is recommended for treatment. Formula: take gastrodia elata 10g, pig brain 1g and japonica rice 250g.

Production method: 1, gastrodia elata cut into pieces. 2. Wash polished rice, put it into the pot with gastrodia elata slices and pig brain, and add water to cook porridge, depending on the maturity of the brain.

How to eat: Take/kloc-0 every morning for 2-7 days. Take it regularly. Oral lecithin tablets and ginkgo biloba leaves.

In order to prevent brain atrophy, blood vessels should be healthy

Atrophy is very common among middle-aged and elderly people, with different degrees. According to experts, brain atrophy is a kind of decrease of brain tissue cells.

Diseases that cause brain nerve dysfunction have the characteristics of hidden onset and progressive aggravation. At the initial stage, dizziness, tinnitus, forgetfulness, insomnia and mood are common.

Symptoms such as impatience; Mid-term memory loss, slow response, indifferent expression, etc. ; In the later stage, there will be obvious mental decline and morphological changes of brain tissue.

Change, even dementia and so on.

Because it's useless to treat stroke with three arthralgia. The famous brain science expert of China Joint Research Association of Heart-Brain Medicine once pointed out: Chinese medicine puts acute and critical diseases in the middle.

Wind is called "closed disease". The so-called "closure" refers to stroke patients with cerebral vascular blockage, brain cells lose nutrition and die, and the whole body meridians are blocked.

As a result, the patient developed hemiplegia, immobility of hands and feet and slurred speech. It can be seen that the "blood, brain and whole body meridians" are blocked, which is called the clock.

Three arthralgia due to wind.

In the past, simple thrombolysis or nerve regeneration could not completely cure the three blockages of stroke, so it was necessary to treat them in three dimensions: blood, brain and whole body meridians.

Stroke. The key to treating stroke hemiplegia and loss of self-care ability is to promote blood circulation, remove blood stasis, awaken the brain, and dredge meridians.

The diagnosis of brain atrophy can start from the following aspects.

1. Symptom diagnosis: Early symptoms include headache, dizziness, gradual memory loss, and decreased judgment of time, place and orientation.

Lack of thinking (such as not being able to find a home after going out) is fragmented, ignoring major issues, entangled in minor issues, mentally retarded, listless and superficial.

Indifferent, unresponsive, lazy, slow-moving, indifferent to things around. Personality change is selfish, subjective and biased.

Persistence, anxiety, paranoia, irritability, incoherent. The patient is forgetful or manic, and even has indecent activities, unstable movements, hands and feet.

Trembling, stumbling, unable to walk in a straight line, incontinence, sexual dysfunction or loss. Have fantasies, hallucinations, auditory hallucinations, aphasia,

Agnosia, and then become senile vascular dementia.

Brain atrophy is mainly manifested as dizziness, headache, dull expression, memory loss, lazy thinking, mental retardation, reduced activity and less words.

Dynamic, unresponsive to peripheral affairs, aphasia, agnosia, auditory hallucination, hallucination and personality change.

Cerebellar atrophy is mainly manifested as dizziness, slow voluntary activity, unstable standing, long stride, stumbling gait, inability to walk in a straight line and language.

Shortcomings, dysarthria, dysphagia, nystagmus, inaccurate grip, inability to move fingers and nose and other cerebellar ataxia symptoms. And has orthostatic hypoxemia.

Stress, syncope, palpitation, perspiration disorder, difficulty in defecation, sexual dysfunction or disorder.

2. Clinical examination and diagnosis: In addition to asking about the medical history and observing the symptoms, patients with brain atrophy can also find that their neurogenic reflexes are different.

The degree of dullness or degradation. Shallow reflexes such as chest and abdomen wall reflexes, testicle-lifting reflexes and anal reflexes are dull, while deep reflexes such as biceps reflex and ulnar reflexes are dull.

Membrane reflex, knee tendon reflex and achilles tendon reflex can also be reduced, and occasionally pathological reflex can occur. Patients with cerebellar atrophy can not be found through clinical examination.

Can stand with feet together, move slowly, lower limbs tremble, can't walk in a straight line, walk in a drunken state, stride and stumble, and have pathological reflex.

Bert's sign (+), finger nose test (+), heel-knee test (+), circle test (+).

3. Imaging diagnosis: CT and MR imaging examination can find that the brain tissue volume is reduced and the ventricle is enlarged. such as

Results Brain atrophy showed that the gap between cerebral cortex and skull plate was enlarged, the sulcus was widened and deepened, the gyrus was flattened and narrowed, and the lateral ventricle and the third ventricle were enlarged.

The density around the anterior and posterior corners of the lateral ventricle decreased. When the cerebellum atrophies, it can show that the texture of the cerebellum is thicker, and the image with reduced volume shows the shape of branches and leaves around the cerebellum.

The low density around the lacuna increased and the fourth ventricle expanded. If there is atrophy of pontine olivary body, the brain stem becomes thinner and narrower, and the surrounding cavity is small.

Olive body becomes wider, flatter or smaller.

(Please refer to the CT/MR atlas of encephalopathy for relevant figures. )

4. Cerebrovascular plastic surgery showed that the cerebral artery was buckled and thinned. The phenomenon of slow blood flow and increased vascular resistance can also be found on the cerebral blood flow surface.

To sum up, it is not difficult to diagnose brain atrophy according to medical history, symptoms, clinical examination and imaging methods.

clinical picture

The onset of brain atrophy is slow and progressive, and it is difficult to determine the onset date of most patients. Clinical manifestations and brain atrophy

The location and degree of occurrence. Among them, diffuse cerebral cortical atrophy is characterized by dementia, mental retardation, memory disorder, personality change and behavior disorder.

Mainly. Some are accompanied by hemiplegia and seizures. Focal brain atrophy is mainly characterized by personality changes; Cerebellar atrophy is caused by language disorder and physical ataxia.

Harmonic tremor is the main factor. Judging from the clinical manifestations of brain atrophy, it can be roughly divided into two categories, one is the decline of brain function, and the other is the decline of intelligence such as dementia.

Can decline. The decline of brain function is manifested as dizziness, headache, insomnia, poor memory, numbness of hands and feet, depression and so on. Manifestation of mental retardation

It is the obstacle of cognitive and social adaptability, such as the decline of memory, understanding, judgment and calculation ability, and even dementia.

(1) Changes in personality and behavior are often the early symptoms of this disease, and patients become withdrawn, unwilling to associate with others, or show it.

Because there is no ideal, no desire, no feelings for children and relatives; Living habits are rigid and weird, personality is impatient, words are increased, or repeated; or

Suspicious and selfish, paying special attention to their own health and safety, often entangled in some minor discomfort. Advanced emotional activities of all patients.

Sense of shame, responsibility, honor, morality, etc. There are different degrees of decline, and the sleep rhythm may also change.

(2) Memory impairment The recent memory defects occurred earlier, such as often losing things and forgetting promised things. With the development of the disease, gradually

Until the memory is completely lost.

(3) Mental retardation and dementia are characterized by the overall decline of intellectual activities such as understanding, judgment and calculation ability, which makes it difficult to adapt to social life.

Capable of working and housework; Gradually, I can't answer my name and age correctly, I don't know if I am hungry, I don't know the way home when I go out, and I collect waste paper.

Sundries are regarded as treasures. In the late stage of illness, I stayed in bed all day, unable to take care of myself, not intimate, incontinence, slurred speech, slurred speech,

Nonsense, and eventually complete dementia.

(4) At the early stage of systemic symptoms, patients often have dizziness and headache, insomnia and dreaminess, soreness of waist and knees, numbness of hands and feet, tinnitus and deafness; Gradually

Slow response, slow action, mumbling, irrelevant answer. In the physical aspect, it is often manifested as aging, white teeth and dry skin.

Hyperpigmentation, even hemiplegia, epilepsy, ataxia, tremor, etc. Neurological symptoms may or may not exist.

In order to prevent brain atrophy, blood vessels should be healthy

Brain atrophy is very common among middle-aged and elderly people, with different degrees. According to experts, brain atrophy is a kind of decrease of brain tissue cells.

Diseases that cause brain nerve dysfunction are insidious and progressive. At the initial stage, dizziness, tinnitus, forgetfulness, insomnia and emotional distress are common.

Symptoms such as impatience; Mid-term memory loss, slow response, indifferent expression, etc. ; There will be a significant decline in intelligence and brain tissue morphology in the later stage.

Change, even dementia, etc.

Vascular disease is the chief culprit of brain atrophy

Brain atrophy is the difference between physiology and pathology. Physiological brain atrophy is the decline of body function, and the function of brain cells gradually declines with age.

Caused by the degradation of the steps. Pathological brain atrophy is a degenerative disease caused by many reasons, mostly vascular diseases.

(such as cerebral arteriosclerosis, cerebral infarction, cerebral hemorrhage, hypertension, coronary heart disease, etc. ), degenerative diseases (such as multiple sclerosis). ), endocrine

Diseases (such as diabetes, hyperthyroidism, vitamin deficiency, etc. ), poisoning (such as metal poisoning, gas poisoning, alcoholism, etc. ), infection (such as brain)

Inflammation etc. ), brain trauma and other causes the destruction of brain parenchyma and the atrophy, deformation and disappearance of nerve cells. Director Du pointed out that the most common cause.

Vitamins are cerebrovascular, cardiovascular and peripheral vascular diseases caused by vascular diseases, which will affect the blood of the whole body.

Circulation, leading to cerebral arteriosclerosis, ischemia and even infarction. , so that brain tissue is damaged due to lack of necessary nutrition, leading to brain work.

Can reduce or even brain atrophy.

Prevent brain atrophy

Actively prevent and treat vascular diseases: to prevent brain atrophy, we should actively prevent and treat some systemic diseases, especially those that affect vascular health.

Such as hypertension, diabetes, hyperlipidemia and arteriosclerosis. Early detection, diagnosis and treatment can delay and control the disease.

The development of. Light is to adjust lifestyle, improve nutritional structure and correct bad living habits; If it is serious, we should control the drugs. Of course, drugs should be followed.

The order is gradual and continuous.

Increase social activities: Give up what you use, read newspapers frequently, write and calculate, run your brain regularly, and constantly promote your nerves and feelings.

Active official information campaign is conducive to improving the blood circulation of the brain, delaying the aging of brain cells and delaying the process of brain atrophy. Actively participate in all kinds of

A kind of social activity, "The more socializing, the healthier the body and mind". Director Du suggested that middle-aged and elderly people should go to the society and increase outdoor activities.

Moving opportunities and stimulating the cerebral cortex to produce new exciting points can delay aging and slow down the decline of brain function.

Light diet and unobstructed stool: constipation is one of the most common causes of cardiovascular and cerebrovascular accidents, which are harmful to brain tissue.

Injury is the most direct and serious. Therefore, Director Du believes that it is very important for middle-aged and elderly people to keep their stools unobstructed. You can eat more fruits and vegetables at ordinary times.

Diet is light, constipation can be combined with drinking some intestinal tea, senna and so on. In addition, Chinese herbal medicines such as Ginkgo biloba and Salvia miltiorrhiza are very important for prevention.

Brain atrophy also plays a role.

The following work should be done to prevent brain atrophy in the family.

① Strengthen nutrition, improve nutritional status, and maintain a balanced diet and mental health;

(2) read more books and newspapers, often participate in group activities, and moderately participate in exercise;

③ Enhance cognitive activities, and strive to restore the previous life experience and ability;

(4) Enhance the patient's orientation, and avoid going out alone if the orientation disorder is serious;

⑤ Promote language communication and assist patients to increase interpersonal communication, such as participating in recreational activities and outdoor activities;

⑥ Keep dangerous goods properly, reduce the changes of indoor items and ensure the safety of patients;

⑦ Pay attention to cleaning to maintain the integrity of patients' skin.

Brain atrophy belongs to the category of dementia, forgetfulness, dizziness, flaccidity and tremor in traditional Chinese medicine. Chinese medicine believes that although the disease is located

In the brain, but it is closely related to the functions of various zang-fu organs, and the pathological mechanism belongs to the deficiency of essence and excess of substance. Clinically, brain atrophy can be divided into five types. Deficiency of kidney essence,

Pituitary empty type: mainly manifested as dizziness, tinnitus, fatigue, soreness of waist and knees, scorched hair, pale tongue with white fur, weak or heavy pulse. manage

It should nourish liver and kidney, benefit essence and strengthen brain. Medicinal Radix Rehmanniae Preparata, Cornus officinalis, Rhizoma Dioscoreae, Radix Polygoni Multiflori Preparata, Carapax et Plastrum Testudinis, Fructus Lycii, Mulberry, Radix Polygalae, Rhizoma Acori Graminei, and Rhizoma Dioscoreae.

Achyranthes bidentata and other water decoctions. Insomnia and dreaminess plus Ziziphus Spinosae Semen, Os Draconis and Concha Ostreae; Radix Astragali, Scorpio and Lumbricus are added for hemiplegia; Cortex Cinnamomi and Radix Aconiti Lateralis Preparata are added to cold limbs.

Deficiency of qi and blood and brain marrow: mainly manifested as pallor, listlessness, salivation, insomnia, anorexia, numbness of limbs, dull expression and reticence.

Naughty movements, shortness of breath, lazy speech, pale tongue with thin coating and slow pulse. Treatment should benefit qi and nourish blood, improve intelligence and strengthen brain. Medicinal Ginseng, Atractylodis Rhizoma, Poria, Radix Angelicae Sinensis, Radix Paeoniae Alba

, Chinese yam, Polygonatum sibiricum, Radix Astragali, Arillus Longan, Semen Ziziphi Spinosae, Placenta Hominis, Fructus Alpinae Oxyphyllae, etc. Radix Puerariae is added for stiff neck swelling; Ligustrum lucidum dry stool

Son, cassia seed.

Yin deficiency and hyperactivity of fire, brain atrophy type: mainly manifested as impatience and irritability, insomnia and dreaminess, dry throat, dizziness and tinnitus, dry eyes and skin.

The tongue is dry and red with little moss, and the pulse is thready. It is advisable to nourish yin and reduce fire, replenish marrow and strengthen brain. Medicinal Cortex Phellodendri, Rhizoma Anemarrhenae, Radix Rehmanniae, Cortex Moutan, Radix Scrophulariae and Fructus Ligustri Lucidi

Lycium barbarum, keel, oyster, pig iron, etc. Tremor plus tortoise shell; Lumbar and knee pain, Eucommia ulmoides and Cornus officinalis; Foolish people are often added.

Pu he yuan zhi.

Obstruction of phlegm in the middle, blinding the brain: mainly manifested as head weight dizziness, chest tightness, shortness of breath, fatigue and lethargy, numbness or heaviness of limbs, pale tongue with white fur.

Tired, slippery pulse. Treatment should eliminate phlegm and turbidity, and enlighten the mind. Rhizoma Pinelliae, Pericarpium Citri Tangerinae, Poria, Caulis Bambusae, Fructus Aurantii, Cortex et Radix Polygalae, Radix Curcumae, Rhizoma Acori Graminei, and Dannan.

Star soup. Radix Salviae Miltiorrhizae and Rhizoma Chuanxiong are added for patients with dark tongue; Eat less hawthorn and chicken gizzard-membrane; Abdominal distension with radish seeds.

Blood stasis, brain failure: mainly manifested as purple lips, numbness of limbs, forgetfulness, thirst and excessive drinking, inversion of language, or chronic illness.

Compound aggravation, dark purple tongue or petechiae, thin white fur, thin or astringent pulse. Treatment should promote blood circulation, remove blood stasis, dredge collaterals and refresh the brain. Medicinal angelica, red peony root,

Chuanxiong rhizome, peach kernel, safflower, salvia miltiorrhiza, polygala tenuifolia, Acorus gramineus, Spatholobus stem, Bupleurum root, Achyranthes root, etc. Urine out of control plus Alpinia oxyphylla; disarray

Adding Rhizoma Polygonati and Scorpio; If you can't see clearly, add chrysanthemum and medlar.

After years of clinical summary, all the cases treated by CT have improved obviously after treatment.

Nursing care of senile brain atrophy

Senile brain atrophy is the most common chronic progressive disease in middle-aged and elderly people, which is caused by one or more reasons.

Memory loss, emotional instability, decreased thinking ability and attention caused by hypoxia, decreased brain tissue volume and decreased number of brain cells.

It is characterized by inability to concentrate, serious development into dementia, language disorder and eventually mental loss. This disease mostly occurs in patients over 50 years old.

The course of the disease can exceed several years or even 10 years, with more women than men.

Brain atrophy, that is, "senile brain atrophy", is a manifestation of brain aging in the elderly. Regarding treatment and maintenance, we should pay attention to the following aspects:

1, pay attention to self-maintenance, such as: regular life, pay attention to reasonable diet, exercise properly, avoid smoking and drinking, and eat less high fat.

Diet, etc.

2. Take anti-platelet aggregation agents, such as enteric-coated aspirin, aspirin or poliovir, to prevent recurrence of cerebral infarction.

If you have gastric ulcer or duodenal ulcer, switch to dipyridamole.

3. At present, you feel dizzy, and you can use some vasodilators, such as Compound Tongmai Drink, Ginkgo biloba and Danshen Dripping Pills to improve it.

Cerebral blood circulation.

Brain atrophy diet therapy soup

1) Stewed mushrooms with fish head: 1 silver carp head, appropriate amount of mushrooms, appropriate amount of fat and seasoning, ginseng powder 3g. Cut the fish head in half and put it in.

Marinate onion, ginger and cooking wine for 2 hours. Put the fat slices, fish heads and mushrooms into a basin, add water and salt, steam in a cage for about 30 minutes, and then

Add shredded cucumber, chopped green onion, coriander, monosodium glutamate Jiang Mo and sesame oil ginseng powder. It can strengthen brain, improve eyesight and improve intelligence, and is suitable for deficiency of kidney yin and marrow sea.

Cause palpitation, insomnia, gait instability, blurred vision, dementia and so on.

2) Pig spine turtle soup: 200g of pig spine, turtle 1 piece, and proper seasoning. Scald the turtle to death with boiling water, shell, viscera and head removed.

Wash paws and pig spinal cord for later use. Put the turtle, onion and ginger into the pot. After the fire comes to a boil, simmer until the soft-shelled turtle is cooked, and then add the pork loin.

Pulping, boiling, adding pepper, monosodium glutamate, refined salt, cooking wine, etc. Cook and take. It can tonify qi and blood, tonify kidney essence, strengthen waist and spine, strengthen brain and improve eyesight.

Sexual dementia, cerebral arteriosclerosis, brain atrophy, etc. It has good nourishing and dietotherapy effects.

Simple self-examination method of cerebellar atrophy

[1] 1. Whether you have cerebellar atrophy, the following simple self-examination methods are recommended. 1. Stand naturally, put your feet together, and finally close your eyes.

Check whether it is smooth.

2. In a straight line, walk forward with the heel next to the toe and observe whether the movement is smooth.

3. Stand on one foot, then close your eyes to see if it is stable.

Preventive measures of brain atrophy

First, keep a good mood and avoid emotional excitement.

Second, don't drink alcohol, spicy, stimulating and other irritating foods, and eat more fresh foods, such as live fish, shrimp, fresh eggs, vegetables and fruits. These are all inappropriate.

Eat dried vegetables and pickles.

Third, avoid heavy physical labor and excessive mental labor.

Four, such as paralysis in bed patients should strengthen nursing, pay attention to health, turn over regularly.

Five, patients should have the confidence to overcome the disease, according to the doctor's advice according to the course of treatment, according to the time to take medicine.

Six, regular inspection when necessary, to understand the development trend of the disease.

Epidemiology of alcoholic brain atrophy

Alcoholism is a common disease all over the world, and its incidence is second only to cardiovascular and cerebrovascular diseases and tumors in Europe and America. Currently in China.

China has not found a more comprehensive incidence statistics. With the gradual improvement of living standards, its incidence in China is also increasing. At present,

The number of patients with nervous system damage caused by alcoholism has increased significantly, and alcoholic brain atrophy is one of them.

With the increase of age, nerve cells can age and die, and the weight of the brain becomes lighter. If you do CT or MRI scan, you can find the brain.

Shrinking volume, widening sulcus, thinning gyrus and expanding ventricles are brain atrophy.