The most helpless thing I have ever seen is that she and it met in the best years, hated each other and killed each other, and they are still inseparable.
He fell in love with her.
It is chloasma.
As far as spots are concerned, it is really easier to grow spots on the Qinghai-Tibet Plateau and more difficult to remove spots. Why?
Take Lhasa as an example. Lhasa is known as the "city of sunshine", with an annual sunshine time of 3005 hours. Sunlight is just one of the chief culprits of long spots. Causes of chloasma:
Gene correlation
Epidemiological studies show that chloasma mostly occurs in people with Fitzpatrick III/IV skin, which means that Asian women are the most prone to chloasma.
Sex hormone level
Chloasma mostly occurs in women, and immune experiments show that the disease has a clear relationship with the level of estrogen and progesterone. Oral contraceptives and pregnancy may aggravate chloasma.
About ultraviolet radiation.
Ultraviolet radiation can induce keratinocytes to secrete paracrine factors such as fibroblast growth factor, endothelin-1 and opioid-melanocortin. In addition, ultraviolet irradiation can also make keratinocytes produce NO and histamine, which can induce the increase of local melanin synthesis.
Skin barrier dysfunction
At the lesion of chloasma, the cells in the basement membrane vacuolated, the expressions of collagen IV and VI decreased significantly, and the free melanin and melanophagous cells in the superficial dermis increased, all of which highly suggested the skin barrier dysfunction.
Inflammation related
Inflammation in chloasma lesions is not manifested by the increase of inflammatory cells such as white blood cells or lymphocytes, but by the increase of the expression of vascular endothelial growth factor in epidermal basement membrane, which can induce the increase of the number, size and density of blood vessels.
What are the manifestations of plateau chloasma?
Low oxygen content: reduce skin resistance and repair ability, accelerate skin aging and pigmentation.
Strong ultraviolet ray: after chloasma treatment, it induces pigment rebound and destroys the repair of skin barrier function after operation.
Air drying: increasing the difficulty of hydrating and moisturizing after chloasma treatment.
Of course, we often say that there is no spot that cannot be removed, only the wrong method is found.
Mistakes in freckle removal:
Searching for freckle in friends circle, Weibo and Zhihu will lead to many fantastic products praised by copywriters, including masks, ointments and skin care products. After long-term use of such products, facial skin will be itchy, burning, dry, peeling and other phenomena. Stop it. Almost all of these products contain glucocorticoids which are forbidden to be added in beauty products. You may have hormone-dependent dermatitis, commonly known as hormone face.
Treating hormone face is a long process. Under the guidance of a doctor, stop using ointment or mask containing hormones, and do a good job in facial cleaning, sun protection and treatment. No freckle can be removed overnight, and everyone has a love of beauty. In addition to loving beauty, we should be vigilant to avoid falling into the sales of inferior cosmetics.