1. Early pregnancy-like reaction: Early pregnancy-like reaction is common, accounting for about 50% of drug users. Most of the symptoms are first severe and then mild, and then gradually disappear, which may be related to the gradual adaptation of the body. At the beginning of taking medicine, a few people have mild early pregnancy-like reactions, such as nausea, dizziness, fatigue, loss of appetite, fatigue, vomiting and so on. It often happens 1-2 weeks after taking the medicine. The reason is related to the temporary excess of estrogen level, resulting in water and sodium retention in the body and gastrointestinal dysfunction. Generally, after taking medicine for 2 ~ 3 months, the reaction can disappear or be alleviated naturally. Taking medicine before going to bed at night can make the reaction lighter during the day. Those with severe reaction can take vitamin B6, 20 mg each time, 3 times a day. If it is still not relieved, you can consider changing birth control pills and choosing drugs with less estrogen content.
2, leucorrhea increase: mostly caused by long-acting oral contraceptives. Therefore, the drug estrogen content is high, and too much estrogen affects the secretory cells of cervix and endometrium, making them secrete vigorously and causing leucorrhea to increase.
3, breast pain: the reason is the stimulation of estrogen on the breast. Elevated estrogen levels in the body can cause breast tenderness. If you encounter this symptom, don't worry, it will get better in a few months. Reducing caffeine intake from coffee, tea, chocolate and drinks can help relieve symptoms.
4. Menstrual disorders: ① Decreased menstrual flow or amenorrhea. This often happens after taking short-acting contraceptives, because drugs inhibit ovulation, the amount of estrogen secreted by ovaries is small, the amount of estrogen contained in drugs is also small, the endometrium can not grow normally, and the endometrium becomes thinner, so the menstrual flow is reduced, and even menopause. Decreased menstrual flow has no effect on health. If you stop menstruating for 2 months in a row, you should stop taking the medicine and use other contraceptive measures, and most of them can return to normal on their own. Menopause often happens after taking long-acting contraceptives. At this time, progesterone drugs such as medroxyprogesterone acetate or norethindrone can be used, and progesterone can also be injected. Short-acting contraceptive No.2 can also be taken twice a night for 5 ~ 6 days. Menstruation usually occurs within one week after stopping taking medicine.
② Breakthrough bleeding. Such as bleeding during medication, mostly after missing medication. A few people will have vaginal bleeding even if they don't miss taking medicine. If it occurs in the first half of the menstrual cycle, it may be caused by estrogen deficiency. You can take ethinylestradiol 0.005 ~ 0.05438+05 mg once a day until you finish taking 22 tablets. If it happens in the second half of the menstrual cycle and is caused by progesterone deficiency, you can take short-acting contraceptives 1 or No.2 1 until you finish taking 22 tablets. If the amount of bleeding is as large as menstrual cramps, you can treat it according to menstrual cramps, stop taking drugs immediately, and start taking drugs next month on the fifth day after stopping taking drugs.
(3) The menstrual flow increases and the menstrual period is prolonged. Often occurs in people who take long-acting oral contraceptives. Hemostatic drugs can be used when bleeding is heavy, and testosterone propionate can be injected when necessary. If menstrual flow continues to increase and bleeding lasts for more than 3 months, long-acting oral contraceptives should be stopped and short-acting drugs should be used instead. When using long-acting injectable contraceptives, irregular menstruation often occurs, such as prolonged menstruation, menorrhagia, shortened cycle, irregular bleeding or amenorrhea, which is more common in the first 3 months of medication. If you can persist in using it, it will gradually return to normal in the future. If bleeding occurs, ethinylestradiol can be added for 3 days.
5. Weight gain: It may be that estrogen leads to water and sodium retention, and progesterone affects anabolism (the increase of progesterone will promote protein assimilation), so some women gain weight. Generally, there is no need to deal with it, and diuretics can be taken orally or given a low-salt diet, and drugs can be stopped if necessary.
6. Pigmentation: A few people have pigmentation on their forehead and facial skin after taking the medicine, which is the result of estrogen and progesterone. Generally, it will recover naturally after stopping taking drugs.
7. Others: breast pain, loss of appetite, nausea, vomiting, headache, dizziness, fatigue, etc. These symptoms are generally mild and last no more than 24 hours. Patients with breast pain and severe headache can be treated with aspirin or other painkillers.
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