The cause of urticaria is complex, and about 3/4 patients can't find the cause, especially chronic urticaria.
1, food and food additives? Mainly animal protein foods, such as fish, shrimp, crab, meat, eggs (or spoiled); Plant foods such as eggplant, bamboo shoots, spinach, apples, plums and other fruits and vegetables. Natural or synthetic substances added to food, such as pigments, condiments, preservatives, yeast, salicylic acid, citric acid, azotetrazine and benzoic acid derivatives.
2. Inhale? Such as pollen, animal dander, feathers, fungal spores, dust, formaldehyde, acrolein, castor powder, pyrethrum and gas, can all cause urticaria, and these patients are often accompanied by respiratory symptoms.
3. Infection? Various acute and chronic infection factors can cause the disease, including:
① Bacterial infections, such as acute tonsillitis, pharyngitis, pustulosis, furuncle, cholecystitis, appendicitis, pancreatitis, sinusitis, etc. It is reported that Helicobacter pylori can indirectly cause the production of autoantibodies, which is related to chronic urticaria. (2) Viruses, such as the precursor phase or jaundice phase of viral hepatitis, are more common. Coxsackie virus infection and infectious mononucleosis are directly related to urticaria. (3) Parasites, such as plasmodium, ascaris, hookworm, pinworm, Entamoeba histolytica, Trichinella spiralis, Giardia lamblia and other intestinal parasites, as well as schistosomiasis, filariasis and echinococcosis.
4. Drugs? Many drugs often cause this disease, such as penicillin, sulfanilamide, serum, vaccine and so on. It's usually an immune response. However, some drugs themselves are histamine releasing agents, such as non-steroidal anti-inflammatory drugs such as aspirin, morphine, codeine, toxigen, polymyxin and so on.
5. Physical factors? Such as mechanical stimulation, cold and heat, sunlight, etc.
6. Insect bites? Wind mass is a prominent symptom of allergic reaction caused by insect bites such as bees and wasps. Caterpillar, beetle, marsupial and moth can also cause blisters when their scales pierce the skin.
7. Mental factors and endocrine changes? Such as mental stress and emotional impulse. Menstruation, menopause, pregnancy, etc. can also suffer from this disease.
8. Medical diseases? 7%-9% of patients with systemic lupus erythematosus have urticaria. In addition, lymphoma, cancer, hyperthyroidism, rheumatoid arthritis, hyperlipidemia and chronic diseases, such as oral cavity, teeth, gum diseases, gastritis, enteritis (allergic colitis, ulcerative colitis), cholecystitis, nephritis, liver disease, ulcer disease, diabetes and so on.
9. Genetic factors? Hereditary urticaria includes hereditary familial urticaria syndrome, familial cold urticaria, delayed familial localized hot urticaria and erythropoietic protoporphyria.
Chronic urticaria is generally considered to be due to the deficiency of qi and blood or yang, and then attacked by wind evil, resulting in rheumatic internal resistance. This is how chronic urticaria comes about. In short, we say that our understanding of Chinese medicine is based on its manifestations and clinical manifestations, and then we diagnose Chinese medicine through syndrome differentiation, and then we can determine that it is a specific and different disease, its different pathological manifestations and pathological mechanisms.