Most people did not respond to vaccination, and only a few children had local redness and pain after injection, which subsided within 1~2 days. A few people have fever, generally below 38℃, and a few people have symptoms such as dizziness, headache and discomfort.

Incidence of occasional rash, angioedema and anaphylactic shock increased with the increase of vaccination times. It usually occurs 10~30 minutes after injection, and rarely exceeds 24 hours. This kind of vaccination reaction is more common in the target of repeated booster injections, especially in children over 7 years old.

Extended data

The main purpose of vaccination is to make the body produce natural biological substances, so as to improve the body's recognition and defense function against pathogens. Sometimes similar pathogens can cause an immune response against the same pathogen, so a vaccine is mainly aimed at a disease or a pathogen with high similarity. For example, smallpox vaccination is a good example. However, since the end of the 20th century, immunologists have discovered that vaccines also have the possibility of treatment, and have developed related research theories and practical applications.

Vaccines can also be used for active immunotherapy. This technology stimulates the immune system to produce a large number of antibodies, or foreign corresponding antibodies, to deal with pathogens in infected patients. Rabies vaccine uses this principle, and this vaccine may also be used as a preventive vaccine. In recent years, studies on cancer and AIDS have found that the surface of diseased cells has different markers from ordinary cells, which may be suitable for treating patients as targets of antibody attacks.

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