Ketogenic diet is not a simple diet therapy for patients with advanced cancer. The metabolism of patients with advanced cancer is disordered, and the ketogenic diet has changed their own metabolic pattern. The body is in ketosis, which is prone to hypoglycemia, ketoacidosis and metabolic disorder. After comprehensive evaluation, ketogenic diet therapy should be started in the hospital.

The so-called ketogenic diet is a diet with high fat ratio, moderate protein and low carbohydrate content, which mainly relies on ketone body, an intermediate metabolite produced by fat metabolism in the liver, to achieve the effect of inhibiting cancer cells. It has a certain auxiliary effect.

Ketogenic diet can specifically target the metabolic changes of tumor cells, and different scholars have confirmed its anti-tumor effect in various tumor models such as brain malignant tumor, prostate cancer, gastric cancer, lung cancer and head and neck tumor.

Ketogenic diet can not only protect normal tissues from radiation and chemotherapy, but also sensitize tumor tissues and maintain skeletal muscle quality of HNSCC patients.