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Can allergic rhinitis be treated?
Global Asthma Prevention Initiative, the Influence of Allergic Rhinitis on Asthma, and the Guidelines for the Diagnosis and Treatment of Allergic Rhinitis (revised and updated by ARIA in 2008) put forward a very important practical concept: Because allergic rhinitis and asthma (or adenoidal hypertrophy or allergic rhinitis asthma syndrome) usually need long-term treatment, parents of allergic patients or children should establish effective and relatively fixed communication channels with doctors so as to communicate the possible problems in treatment in time. At present, in view of the incompleteness of treating allergic rhinitis with simple drugs, non-drug anti-allergic probiotics are proposed to adjust the balance of allergic constitution. It is suggested to supplement Kangminyuan granules composed of anti-allergic probiotics, and adjust the allergic constitution through Kangminyuan, an anti-allergic probiotic, so as to lay the foundation for solving the following common allergic problems!

Website Bian Xiao searched some professional websites for information about the most common problems of allergic rhinitis patients, and summarized the following common problems. The system replies as follows:

1, drug reduction problem:

Asthma, allergic rhinitis, allergic rhinobronchitis, postnasal drip syndrome and adenoidal hypertrophy usually need to be stable for 3-4 months to reduce treatment. Reduction is a slow adaptation process, and corresponding auxiliary methods are also needed to adjust allergies. Drugs control allergic rhinitis, allergic asthma and allergic rhinobronchitis, and at the same time supplement anti-allergic probiotics Kangminyuan to correct immune disorders. Adjusting allergic constitution can help patients easily solve the problem of drug reduction for allergic rhinitis and asthma. The method of anti-allergic probiotics Kangminyuan to assist drug reduction is from the asymptomatic state of medicine to the asymptomatic state of low dose, and then to the asymptomatic state of no medicine. If the drug is reduced too quickly, the disease will recur and all previous efforts will be in vain. Usually every three months to assess the condition, consult a doctor or combine the stable state of allergic rhinitis in remission to decide whether to reduce the amount. For patients and children with asthma, allergic rhinitis, asthma syndrome and allergic rhinobronchitis, it takes 2-3 years to continuously reduce the dose and maintain treatment, while children with simple adenoidal hypertrophy need treatment for at least 4-6 months. Aspirin asthma, chronic obstructive pulmonary disease (emphysema, cor pulmonale), intractable asthma and hormone-resistant asthma take longer.

2. Recurrence or poor initial efficacy:

Strictly follow the doctor's advice and slowly reduce the amount according to the doctor's advice, so the disease will not recur. Recurrence of diseases is usually related to contact with allergens (inhalation or food), respiratory infections (or colds), chemical odors or irritating gases, temperature (cold) and humidity changes, and smog. Secondly, the treatment is not standardized or disjointed, such as poor compliance with the doctor's advice or insufficient dose or excessive reduction for some reasons. It may also be related to the failure of immunotherapy (non-drug anti-allergic probiotics Kangmin source reduces IgE immunotherapy) or desensitization therapy. There is also a very important link about the easy recurrence of diseases: with the improvement of the disease, the treatment methods of patients or children become irregular, the drug inhalation is not in place and the inhalation dose is insufficient, and auxiliary programs such as supplementing Kangminyuan, an anti-allergic probiotic, are the most common and important reasons for the recurrence of asthma, rhinitis or adenoidal hypertrophy. Think carefully, how to effectively and comprehensively control allergic inflammation in the upper and lower respiratory tract when atomized drugs (microgram drugs) are always poorly inhaled? When inhaling through the nose, it should be inhaled during nasal ventilation, and the nasal cavity should be cleaned with physiological seawater nasal cleaner 15 minutes before inhalation. In particular, the nasal cavity must be washed with physiological seawater nasal cavity cleaner, otherwise the inhaled drugs are easy to stick in the nasal cavity, which obviously affects the contact between drugs and mucous membranes, resulting in poor curative effect.

3, the side effects of inhaled hormones:

Because inhaling microgram trace hormones is the fastest and most effective common method to treat allergic rhinitis and control allergic asthma, and it is mainly absorbed through local treatment, so the side effects of inhaling hormones are few. When the recommended therapeutic dose is used correctly, there is no inhibitory effect of inhaled budesonide on adrenal cortex function and hypothalamus-pituitary-adrenal cortex axis, and no side effects similar to Cushing's syndrome, such as edematous obesity, osteoporosis and hirsutism. According to a two-year clinical observation of inhaled budesonide in Britain, the results proved that it would not affect the growth and height of children. ① Rinse your mouth in time after oral inhalation (you should press your mouth once) and spit out the mouthwash is the key measure to avoid the systemic side effects of oral inhaled hormone in the treatment of asthma and allergic rhinitis asthma syndrome. A few patients may have hoarseness, so gargle with throat gargle should be adopted. Very few children occasionally have thrush, which is also related to not gargling in time after inhalation. ② For patients with allergic rhinitis and adenoidal hypertrophy treated by nasal inhalation, drugs may be deposited in the throat when inhaling slowly and deeply, so it is best to rinse your mouth in time after nasal inhalation, and it is also best to wash the nasal vestibule with cotton swab dipped in normal saline (that is, nostril ③ is used for children under 3 and a half years old)

4. About the side effects of antiallergic drugs:

The first generation of antiallergic drugs, such as chlorpheniramine and phenanthrene, have a strong inhibitory effect on the central nervous system and cannot be used for long-term large-dose treatment of asthma, allergic rhinitis and allergic rhinitis asthma syndrome, while the second generation of antiallergic drugs, such as cisplatin, loratadine, terfenadine, cetirizine, ketotifen, etc. ) has obvious cardiotoxicity, which easily leads to sudden cardiac death, and has been gradually stopped abroad. At present, we use levocetirizine, desloratadine, fexofenadine and other third-generation antihistamines, which have high safety, few side effects, are suitable for long-term use and have few side effects, and are the most commonly used drugs in advanced countries abroad. Note (levocetirizine is not cetirizine, desloratadine is not loratadine. Although there is a word difference, the side effects are many times worse. Pay attention to identification)

5. Cold problems during treatment:

During the treatment, if there is yellow phlegm or thick yellow nose or fever, it is usually accompanied by respiratory tract infection or cold. Children with allergies should try not to use antibiotics (because most colds are viral infections, antibiotics are not the first choice, and second, children with allergies have greater side effects). When the patient has yellow nose, stuffy nose or runny nose, the physiological seawater nasal irrigation device can be used to wash the nasal cavity. When dropping the nose, levofloxacin eye drops are used to drop the nose (2 drops on each side), lying flat at the end of the bed, with the head sticking out of the end of the bed backwards and the nostrils facing upwards, and gently dropping the nose for 2-5 minutes to avoid bitter taste when taking the medicine. You can take an alcohol bath if you have a fever below 38.5 degrees, and you can take antipyretics if you have a fever above 38.5 degrees. Most colds can be relieved within a few days after the above-mentioned non-systemic antibiotic treatment. If there are still no signs of remission after treatment, you should go to the local hospital to check the blood routine. The white blood cell (WBC) is high, indicating that the blood picture is usually high, which may be a bacterial infection. You should consider using antibiotics (such as cephalosporins); Low blood count and high lymphocytes may be respiratory virus infection. Only pay attention to drink more water and rest for virus infection. Secondly, if repeated treatment is still not cured, mycoplasma infection should be considered. If mycoplasma antibody is positive, erythromycin enteric-coated tablets can be considered for treatment (azithromycin has heart side effects, so use it with caution). During the treatment of respiratory tract infection or cold, budesonide or antiallergic drugs should not be stopped at will, but immunomodulators (such as jade screen, spleen peptide, chest peptide, Shenqi granule, etc.) should be stopped. You can pause when you have a fever. Symptoms of cough or nasal congestion will worsen during the recovery period after a cold. Adding budesonide to press once can clear nasal discharge or dry cough, and generally it can be recovered within one week without too much medicine. The treatment of yellow or sticky nose is the same as above.

6. Some parents asked that the adenoids have shrunk, but the tonsils are still a big problem. Because tonsils are chronic hypertrophy caused by breathing with your mouth open, and bacterial viruses or allergens are inhaled through the mouth, it is necessary to breathe without your mouth open for a period of time after adenoids are treated for atrophy. This chronic tonsil hypertrophy is different from the hypertrophy of acute tonsillitis. Usually, the drug effect is not good, but it takes time to recover.

7. Time and efficacy of desensitization therapy and immunotherapy:

Usually desensitization treatment takes 2-3 years, so it is necessary to insist on treatment. Desensitization therapy and immunotherapy can not cure allergic constitution, but a treatment method to treat allergic diseases by improving allergic constitution. Although it is difficult to cure, it has a radical effect and can effectively improve the condition. Desensitization therapy includes sublingual drip and injection. Immunotherapy mostly adopts oral therapy. Patients who are usually over 4 years old and are mainly allergic to dust mites are suitable for desensitization treatment. Immunotherapy (including traditional Chinese medicine immunotherapy and biological agents) is suitable for children and adults over 2 years old, and it also needs at least 3 or 6 months of treatment. Immunotherapy for adults takes longer. Immunotherapy drugs usually have no or few side effects. There are few side effects of desensitization therapy.

8, treatment problems:

Allergic disease is caused by allergic constitution, which is a chronic disease and needs long-term treatment. Everyone's course of treatment varies according to their illness (severity and complications), such as asthma complicated with allergic rhinitis, adenoidal hypertrophy complicated with allergic rhinitis or bronchitis, and even allergic rhinitis, allergic conjunctivitis, allergic asthma, adenoidal hypertrophy, eczema, etc., so the specific course of treatment is different. At present, the popular treatment schemes in the world are individualized treatment schemes, and the length of each course and several courses varies with the illness, and this scheme is usually a long and continuous process, so it needs the close cooperation of doctors, patients and parents of children.

9, the special significance of immune regulation in allergy treatment:

Lactobacillus salivarius and Lactobacillus Grignard, an antiallergic probiotic strain, were combined into Kangminyuan probiotics, which created a new non-drug antiallergic microecological immunotherapy.

Allergy is an invisible killer that destroys the immune system. Repeated allergy can highly activate human immune cells and induce various inflammatory reactions, such as allergic rhinitis, allergic asthma, eczema in children, urticaria and allergic dermatitis caused by drugs, cosmetics, food and pollen allergy. Studies have shown that the number of Lactobacillus salivarius in people with allergic constitution is much lower than that in people with healthy constitution, which is a prerequisite for allergic reaction. The lack of Lactobacillus salivarius in human body will increase IgE antibody in serum, and the secretion of IFN-γ in spleen cells will be insufficient, thus inducing various allergic reactions in skin and mucosa. Dr. Su, a doctor of biotechnology in Dongyu, Taiwan Province, found that the number of Lactobacillus salivarius in human intestine is sufficient, and there will be no allergic reaction after continuous contact with allergens; Lactobacillus salivarius supplementation is directly related to the occurrence and severity of allergic reactions.

Four major medical centers in Taiwan Province Province confirmed that 1 was helpful to reduce the production of specific IgE antibodies in serum by quantitatively supplementing Lactobacillus salivarius to allergic children. 2. It is helpful to promote the secretion of IFN-γ by spleen cells. After 3 months of supplementation, the number of Salivary bacilli in allergic children basically reached the normal value, and the follow-up showed that allergic children did not have allergic reactions within 3 years. Lactobacillus salivarius is a natural strain extracted from the digestive tract of healthy children, which is safe and efficient, and can be used as a supplement for infants and pregnant women. Kangminyuan Probiotics, a health food developed by Dongyu Biotechnology in Taiwan Province Province, is mainly composed of compound bacteria particles of Lactobacillus salivarius and Lactobacillus Grignard, which greatly reduces the individual differences of allergies. This kind of antiallergic probiotic has been listed on the mainland, and this product can't replace medicine.

10, exercise:

Exercise is an important measure to increase physical fitness and physical resistance, and immunization or desensitization therapy can complement each other to improve allergic physique. Sports suitable for asthma and allergic rhinitis patients or children include swimming, morning running, Tai Ji Chuan, yoga, qigong, badminton relaxation, breathing gymnastics and broadcast gymnastics. Swimming is mild, which can not only exercise physical fitness, but also regulate breathing exercise and cold-resistant exercise. However, people with allergies are often allergic to disinfectants. Swimming pools are usually disinfected in the morning, so it is best to swim in the afternoon or at night. Yoga, Qigong and Tai Ji Chuan can also adjust breathing and endurance exercise. For other sports, such as morning running and badminton, the heart rate should not exceed 100 beats/minute.

1 1, dietary problems:

There is no need to strictly avoid food with mild allergy, and the principle of eating less, fresh and heating should be followed. Eating less (the key is to control the amount of food) can produce tolerance (antibodies) and gradually stop allergies. For example, if you are allergic to milk, you can take 1 ml every day first, 2 ml every day in the second week, and 4 ml every day in the third week ... If you are allergic to a certain dose, you can reduce one dose and add it in one phase. The same is true of other foods. Don't eat seafood in the refrigerator. Eat fresh seafood instead of raw. For some foods that can induce severe allergies and are not often eaten, avoid eating them, such as mango, silkworm chrysalis, buckwheat, peaches and so on. Allergic patients should not eat too spicy food. Patients with cough and asthma should not eat sweet, salty and cold food. Give children ice cream and sorbet. You can eat them, but you should eat less at first. For example, eat 1/8 ice cream or sorbet every day for the first week, and eat 1/4 ice cream or sorbet every day for the second week, so that children can gradually adapt to it and increase their cold tolerance.

12. Conclusion

The change of children's illness often requires parents' patience and long-term careful observation, and the judgment of the severity of illness and the change and increase or decrease of drug dosage in the treatment plan are often decided by doctors and implemented by parents, which requires parents and doctors to have a more effective and fixed communication channel. At present, a patient in most hospitals only sees the disease for a few minutes, and the outpatient service often changes the doctor's medical mode, which is very unfavorable for the continuous observation, long-term treatment and accurate reduction of chronic diseases such as asthma, allergic rhinitis and adenoidal hypertrophy. Children with hereditary allergic constitution tendency should pay attention to the adjustment of allergic constitution after allergic symptoms appear. Non-drug immunomodulation can supplement anti-allergic probiotics Kangminyuan on weekdays to adjust allergic constitution, help reduce allergic manifestations, prevent allergies and reduce the occurrence of allergic diseases.