High-intensity training will interfere with the immune system and increase the levels of lactic acid and ammonium in the body. High levels of ammonium can affect muscle function. In the first five minutes of training, glutamine levels will rise and catabolic hormones will be released. But the bad news is not limited to this for trainers, because even after training, muscles will continue to release glutamine, which will lead to their weight loss in a strict sense. The higher the training intensity, the faster the loss rate. As a sports and fitness enthusiast, it is important to remember that the loss of glutamine is not only caused by disease, but also by stress caused by exercise.

For athletes, plasma glutamine level is an important index to evaluate whether they overtraining. When bodybuilders and other athletes engage in high-intensity strength training, the glutamine level in the body can be reduced by 50% (it will take several hours to recover to the original level). At this time, if you can't get enough glutamine through diet or self-synthesis, you will decompose muscle protein to meet the body's demand for glutamine. This not only affects the volume of muscle, but also reduces the immune ability of the body, because glutamine in the immune system is mainly released from skeletal muscle. After a long period of exhaustive exercise, the plasma glutamine level is even lower, and some people may maintain the low level for weeks, months or even years.