It is scientifically proved that the IgE immunoglobulin in the immune system of patients with urticaria is 1- 10 times higher than that of normal people. These higher IgE will disturb the immune system of human body and make it sensitive, which will lead to urticaria. Probiotics can effectively inhibit the abnormality of IgE immunoglobulin, reduce allergen-induced IgE production, and finally play a role in preventing and treating urticaria.
Urticaria often begins with itchy skin, followed by wheal, which is bright red or pale, and a few may have edematous erythema. It usually subsides within 2 ~ 24 hours, but new rashes appear repeatedly. The course of the disease is delayed for several days to several months. The size and quantity of rash are uncertain, and it can appear in any part of skin and mucosa. Rash causes severe itching, tingling or burning sensation, but the degree varies from person to person. Severe cases have headache, fever and other systemic symptoms.
Diagnosis of urticaria
Urticaria is easy to diagnose, but it is difficult to determine the cause. Check-ups are usually done: ask about the medical history, detect the determination of antinuclear antibody and IgE antibody, and positive IgE antibody is very helpful for the diagnosis of urticaria.
Common causes of urticaria
There are many causes of urticaria, including various foods, drugs, infections, visceral diseases, physical factors (cold, heat, light, etc. ), mental factors and genetic factors. The common causes of urticaria in children are as follows.
1. food: animal food, such as fish, shrimp, crab, milk and other seafood; Plant foods, such as beans, mushrooms and some fruits. Urticaria caused by eating stale food is particularly common in children, which may be related to the imperfect gastrointestinal function of children and the fact that deteriorated foreign proteins are more likely to produce allergic reactions.
2. Drugs: acute urticaria may occur when taking or injecting certain drugs. Commonly, there are antibiotics, antipyretic and analgesic drugs, sulfonamides, serum products, vaccines and various enzyme preparations.
3, infection: including viruses, bacteria, fungi, parasites, such as children's upper respiratory tract virus or bacterial infection, tonsillitis, otitis media, alveolar abscess and skin purulent infection.
4. Inhalation: Inhalation of animal dander, pollen, dust, feathers, fungal spores, etc. Children with ectopic quality are prone to allergic asthma and urticaria.
5. Visceral and systemic diseases: such as rheumatic fever, rheumatoid arthritis, systemic lupus erythematosus, infectious mononucleosis, metabolic disorder, endocrine disorder, malignant tumor, etc. It can cause urticaria, especially chronic urticaria.
How should urticaria be treated correctly?
At present, the measures to treat urticaria mainly include removing inducing factors, inhibiting mast cells from releasing mediators, and controlling inflammatory reactions. Supplementing anti-allergic probiotic Xinmin Kang to reduce serum IgE antibody and systemic anti-allergic combined therapy are beneficial to shorten the treatment cycle of urticaria.
Urticaria mostly belongs to type I allergic disease (also known as IgE-mediated allergic reaction), and its etiology is complex. Generally, it will change from acute urticaria to chronic urticaria, which will recur for a long time, but it will not heal after long-term treatment. At present, people only pay attention to the treatment of urticaria, but not to the allergic reaction itself: the stimulation of allergens leads to the disorder of human immune function and the abnormal increase of immunoglobulin E in the body. Repeated contact with allergens leads to a large number of IgE antibodies in the body and attached to immune cells for a long time, which leads to the secretion of inflammatory mediators such as histamine and harms itself. From the immunological point of view of urticaria, the fundamental treatment should be to control IgE. At present, the treatment of urticaria mostly stays in the inflammatory stage such as antihistamine, and some people will try to treat it by improving immunity, but allergy is not caused by low immunity, and the imbalance of five immunoglobulin secretion in human body is the fundamental cause of the disease. At present, the treatment method of IgE anti-human antibody to solve urticaria in international immunology research is to supplement a large number of anti-allergic probiotics to reduce IgE antibody in human body, and adjust the balance of immunoglobulin by stimulating interferon secretion, so as to restore the correct immune response of human body and finally make it no longer allergic.
Urticaria should develop good living habits in life, especially the following points:
1, avoid known allergens, avoid cold, spicy, seafood, drinks and other foods in diet and daily life, and pay attention to keeping indoor and outdoor clean and sanitary, keep fewer pets such as cats and dogs, and avoid inhaling pollen and dust. In addition, emotional excitement will aggravate the baby's skin vasodilation and stimulate or aggravate urticaria.
2. Help children develop good eating habits, eat more fresh and beneficial fruits and vegetables (dark fruits and vegetables contain more natural antioxidants, which help stabilize mast cells and improve allergic symptoms) and soy products (high-quality plant protein). And stay away from some sensitive seafood, pickled foods and foods with excessive artificial additives.