1. contraindications (1) are allergic to this drug or similar drugs. (2) Disabled in case of bleeding caused by 2)DIC. (3) Although the drug has not been reported to promote thrombosis, for safety reasons, it is prohibited for those with a history of thrombosis or embolism. (4) Bleeding caused by blood diseases should not be used. (5) Not suitable for pregnant women unless there is an emergency.

2. High-risk groups of thrombosis (elderly, obesity, hyperlipidemia, heart disease, diabetes, cancer patients) should be used with caution (1). (2) Interventional treatment of vascular diseases and heart surgery. (3) Surgery requiring long-term immobilization after surgery (such as lower limb bone and joint surgery) is easy to induce deep vein thrombosis.

3. The effect of drugs on breastfeeding is not clear.

4. Before and after medication and during medication, it is necessary to check or monitor the bleeding and coagulation time of patients during medication.

counteraction

1. The incidence of adverse reactions is low, with occasional allergic reactions.

2. When the drug is used in unconventional doses (more than 5 times), it can cause the decrease of fibrinogen and blood viscosity, so the high-dose treatment is still controversial.

drug interaction

It's not clear yet.