Unsaturated fatty acids such as linoleic acid, oleic acid and linolenic acid are found in safflower oil. Oral administration of safflower oil (65438±0g/kg/kg body weight per day) in rabbits with hypercholesterolemia has a very obvious effect on reducing their serum total cholesterol and triglyceride levels. Usually the dosage is 20 ml, three times a day, mixed with vegetables or taken orally for 4 ~ 5 months, and the effective rate of lowering cholesterol can reach 72%. Once the drug is stopped, even if it is only half a month, it will pick up.

2. Yan Weizi

The fruit of Leonurus heterophyllus is Fructus Leonuri, and its oil content is 37% (unsaturated fatty acids such as oleic acid and linoleic acid). Guanweizi, commonly used in clinic, is a granule. The daily dose is equivalent to 30 grams of crude drugs, and the course of treatment is 1 month. The effect of lowering triglyceride is better than that of lowering cholesterol, and the adverse reaction is small. All types of hyperlipidemia in the elderly are suitable.

3.turmeric

Turmeric can not only promote bile secretion, but also its extract can obviously reduce the blood cholesterol content of experimental hyperlipidemia animals. Turmeric alcohol extract, volatile oil and curcumin all have the effects of lowering blood cholesterol, triglyceride and β lipoprotein, especially triglyceride, which can reduce the contents of aortic cholesterol and triglyceride.

4. Polygonum cuspidatum

Emodin contained in Polygonum cuspidatum can reduce exogenous cholesterol entering the body, which is also the reason why animal experiments show that Polygonum cuspidatum has obvious lipid-lowering effect. Clinical reports show that Polygonum cuspidatum has been used to treat hyperlipidemia 124 cases, and the effective rate of lowering cholesterol is between 47. 1%- 100%, and it also has the effect of lowering triglyceride, and the effective rate is between 27.2% and 83.3%.

garlic

Garlic is a kind of seasoning, and its effective component is garlic essential oil, which has a good inhibitory effect on the increase of low-density lipoprotein caused by arterial lipid hyperplasia and cholesterol, can prevent the decrease of lipoprotein, and can also significantly reduce the content of aortic cholesterol and relieve aortic atherosclerosis.

6.evening primrose

Evening primrose oil is extracted from evening primrose seeds and contains 75% γ -linoleic acid and 7% ~ 9% γ -linolenic acid. γ -linolenic acid is a precursor of prostaglandin, which has physiological activities such as reducing blood lipid, antithrombotic and improving hemorheology. Clinical application shows that taking 2g each time, twice a day, can make the total effective rate of lowering cholesterol reach 68.2%, lowering triglyceride reach 865438 0.5%, and can increase high-density lipoprotein, but it can't help obese people lose weight. All types of hyperlipidemia in the elderly can be applied to evening primrose.

7. Polygonum multiflorum Thunb

Polygonum multiflorum Thunb. Contains chrysophanol, emodin, rhein, etc. It is the root of Polygonum multiflorum Thunb. Polygonaceae can promote intestinal peristalsis, accelerate cholesterol excretion, and weaken cholesterol absorption capacity, thus achieving the effects of reducing blood fat and resisting atherosclerosis. The clinical application of Polygonum multiflorum Thunb is far superior to that of decoction. Oral administration of 5 tablets, 3 times a day, 1 ~ 3 months, the effective rate can reach 89%. After stopping the drug, the blood lipid has increased, so we should insist on taking the drug after receiving the curative effect to maintain the curative effect. It is precisely because Polygonum multiflorum Thunb has the function of tonifying liver and kidney that it is especially suitable for elderly hyperlipidemia patients with liver and kidney yin deficiency and dry stool. Polygonum multiflorum Thunb can also be widely used in a large number of clinical patients as a lipid-lowering prescription.

8. Alisma orientale

Alisma orientalis has a good hypolipidemic effect, which has been confirmed in clinical and experimental studies of hyperlipidemia in China and Japan. According to the treatment of 135 cases of hypercholesterolemia and 127 cases of hypertriglyceridemia in Shanghai and Hangzhou, the effective rates were as high as 88% and 72% respectively. The experimental study shows that Alisma orientalis can obviously inhibit the formation of atherosclerotic plaque in rabbits and the content of blood cholesterol, and also inhibit the absorption of cholesterol in mice intestine and the synthesis of cholesterol in vivo, which is also very beneficial to the operation and excretion of cholesterol and has the effect of interfering with the absorption, decomposition and excretion of cholesterol.

9.hawthorn

As we all know, hawthorn is a red fruit with sour taste and appetizing effect. Besides edible, it has many medicinal values. Hawthorn is made into various preparations abroad for treating hyperlipidemia and coronary heart disease. Domestic rabbit experiments have proved that the alcohol preparation and total saponins contained in hawthorn have antihypertensive and lipid-lowering effects on atherosclerosis and can reduce lipid deposition.

10. Cassia seed

According to relevant medical reports, cassia seed decoction and syrup are used to treat hypercholesterolemia 100 cases, and the total effective rate is as high as 98%. Many experiments have proved that cassia seed has a good inhibitory effect on the increase of blood cholesterol and the formation of atherosclerotic plaques. The lipid-lowering effect is probably related to the fact that aloe-emodin and emodin rich in cassia seed can promote intestinal movement and inhibit cholesterol absorption.

1 1. Chen Yin

In Tianjin and other places, Herba Artemisiae Scopariae was used instead of tea or tablets to treat hypercholesterolemia 104 cases, which proved that this product had obvious effect of lowering blood cholesterol. Coumarin compounds contained in Herba Artemisiae Scopariae have lipid-lowering activity, which can fully reduce animal serum cholesterol and relieve and control arteriosclerosis.

12. Artificial Cordyceps sinensis

Cordyceps sinensis is a kind of fungus, which parasitizes on the substrate formed by bat moth larvae and dries with the rigid body of the larvae. Artificial Cordyceps sinensis is the mycelium of Cordyceps sinensis, a fungus of ergotaceae, which was isolated from fresh Cordyceps sinensis samples collected in Qinghai. Many clinical experiments have proved that it can reduce blood lipid and inhibit the formation of atherosclerosis. Clinical application of pills, three pills each time, three times a day for 1 ~ 2 months, showed that the effective rate of lowering cholesterol was 6 1.2%, the effective rate of lowering triglyceride was 56.7%, and the high-density lipoprotein increased by nearly 27. 19%. All types of hyperlipidemia in the elderly are suitable for artificial cordyceps sinensis.

13. myrrh

Myrrha is the gum resin of Myrrha in Oleaceae, containing 25% ~ 35% resin and 2.5% ~ 10% volatile oil. Animal experiments show that this medicine can obviously reduce the cholesterol of rabbits, prevent the formation of atherosclerotic plaques and lose weight. Clinical observation also has obvious cholesterol-lowering effect, but the curative effect on triacylglycerol is uncertain. After myrrh treatment, the patient's high density lipoprotein can't increase slightly. Fortunately, it has obvious effect of reducing plasma fibrinogen, and it is effective for fibrinolysis secondary to hypercoagulable state. Therefore, myrrh is suitable for elderly patients with hypercholesterolemia complicated with coronary heart disease and angina pectoris.

14. Ligustrum lucidum

Ligustrum lucidum is the fruit of Ligustrum lucidum, a plant of Oleaceae, which has a good effect of lowering cholesterol and triacylglycerol, and can make experimental atherosclerosis disappear. Honey pills used in clinic can reduce cholesterol and low density lipoprotein, and have no obvious adverse reactions. It is suitable for elderly patients with hyperlipidemia and asthenia, and the effect is better.

15. Silymarin

Silymarin is a total flavone extracted from the seeds of Silybum marianum. A large number of experiments have confirmed that this drug can not only reduce the concentration of cholesterol in blood, but also further remove lipid deposits in liver and kidney tissues. It has a good effect on lowering cholesterol and triacylglycerol in clinic, and is quite effective on hyperlipidemia and fatty liver in the elderly.

16. rhubarb

Rhubarb is the root of Polygonaceae, and its effective components and lipid-lowering mechanism are similar to those of Polygonum multiflorum Thunb. Clinically, patients with hyperlipidemia are given rhubarb powder orally, 0.25g each time, 4 times a month. After 1 week, it will be reduced to three times a day, and the course of treatment will be 1 month. The effective rate of reducing cholesterol was 84%, and triglyceride also decreased to some extent. Rhubarb is suitable for some people with excess and dry stools, and the elderly have more blood stasis, which will cause disease. Although rhubarb is a blood-breaking drug, it can completely tonify diarrhea if used properly. As the saying goes, "catharsis can strengthen the body, and turbidity can prolong life."

17. Ganoderma lucidum

Ganoderma lucidum often uses the whole plant of Ganoderma lucidum or Ganoderma lucidum, and the submerged Ganoderma lucidum is processed into syrup or tablets by culture fermentation broth and mycelium, which is widely used in clinic. Ganoderma lucidum can obviously alleviate experimental hyperlipidemia and inhibit the formation of atherosclerosis to some extent. In clinical application, the effective rate of lowering cholesterol is 84% ~ 86%, and the effective rate of lowering triglyceride is 50% ~ 7 1%. Hyperlipidemia due to senile deficiency syndrome is applicable.

18. Pollen Typhae

Pollen Typhae is the stamen (including flower seeds) of Typha longibracteata, which can inhibit the absorption of foreign cholesterol in intestine and further reduce blood lipid. It is worth noting that only raw Pollen Typhae is effective, but Pollen Typhae and dregs are ineffective. 30 grams of crude drug is equivalent to 1 ~ 2 months of daily dosage of tablets or granules used in clinic, which has a very obvious effect on lowering cholesterol. The elderly with hyperlipidemia, partial excess syndrome, coronary heart disease or obesity are all suitable for taking Pollen Typhae.