Zhibitai capsule consists of red yeast, hawthorn, Atractylodes macrocephala and Alisma orientalis. Has the effects of resolving phlegm, removing blood stasis, invigorating spleen and regulating stomach. Indications: Hyperlipidemia caused by phlegm and blood stasis and unfavorable qi and blood, with symptoms such as dizziness, chest tightness, abdominal distension, anorexia, mental fatigue and so on.
The origin of the prescription of Zhibitai Capsule can be traced back to the ancient prescription "Alisma Decoction" in the synopsis of the golden chamber by Zhang Zhongjing, a medical sage. On the basis of the ancient prescription "Alisma Decoction", red yeast and hawthorn are added, which is refined by modern scientific and technological means. Traditional medicine believes that the basic pathogenesis of hyperlipidemia is the mixture of excess and deficiency. Zhibitai capsule has the functions of invigorating spleen, eliminating dampness, promoting blood circulation and removing blood stasis, and is used to treat hyperlipidemia.
Modern pharmacological research shows that special red koji contains 15 kinds of natural monacolin homologues, among which natural monacolin K has the strongest effect, while natural monacolin K is acidic lovastatin, which indicates that Zhibitai capsule actually contains statins and has a clear lipid-lowering effect.
The main effective components in hawthorn are flavonoids, triterpenoids and organic acids. Triterpenoids and flavonoids have the effects of lowering blood lipid, protecting blood vessels, dilating coronary arteries, improving myocardial function and lowering blood pressure. Oleanolic acid and ursolic acid in triterpenoids have good liver protection, enzyme reduction and anti-inflammatory effects. Triterpenoid ursolic acid and flavonoid hyperin can improve the activity of superoxide dismutase while reducing blood lipid, thus improving vascular endothelial function, which is beneficial to the prevention and treatment of cardiovascular diseases.
Alisma orientalis can reduce plasma total cholesterol, which may be due to inhibiting the absorption of exogenous total cholesterol, interfering with the metabolism of endogenous total cholesterol and resisting lipid peroxidation. Atractylodes macrocephala can obviously inhibit platelet aggregation and is beneficial to the treatment of atherosclerosis. At the same time, its lipophilic extract has obvious effect on reducing plasma total cholesterol and LDL-C levels and increasing HDL-C levels.
The compatibility of the four traditional Chinese medicines is reasonable and just right, which makes Zhibitai have the functions of reducing blood lipid level, relieving physical and mental fatigue and general weakness, invigorating spleen and regulating stomach, and improving gastrointestinal metabolism and absorption capacity. In addition, Zhibitai can also inhibit cholesterol synthesis, reduce the absorption of cholesterol and triglycerides, promote cholesterol metabolism, improve vascular endothelial function, eliminate carotid plaque, promote insulin release and lower blood sugar.
Jiangzhi Tongluo Soft Capsule, the main component of which is turmeric extract, has the effects of promoting blood circulation, promoting qi circulation, reducing blood lipid and removing turbidity. It is suitable for hyperlipidemia, with symptoms of chest pain, tingling in precordial area, chest tightness, petechiae or ecchymosis on the tip of the tongue, and thready and astringent pulse. It belongs to blood stasis and qi stagnation.
Modern pharmacological research shows that curcumin can inhibit the synthesis of cholesterol and fatty acids, promote the transformation from fat to sugar, improve the activities of plasma lipolytic enzyme, lipoprotein esterase and liver esterase, and accelerate the metabolism of triglycerides and triglycerides-rich lipoproteins, thus playing a role in lowering blood lipid, and has pharmacological effects of scavenging free radicals, anti-inflammatory, anti-oxidation, anticoagulation, promoting fibrinolysis and inhibiting the proliferation of vascular smooth muscle cells.
Curcumin and its derivatives can reduce total cholesterol, triglyceride, low-density lipoprotein cholesterol and increase high-density lipoprotein cholesterol. It can improve the risk factors of atherosclerosis (lipid regulation, blood pressure reduction, etc.). ) and anti-atherosclerosis (anti-inflammatory, anti-oxidation, anti-platelet aggregation and protection of endothelial cells), both of which have synergistic effects. It plays an important role in the prevention and treatment of cardiovascular and cerebrovascular diseases, and it is also found that curcumin can resist the damage of oxygen free radicals to liver cells, thus protecting liver cells.
For patients with hyperlipidemia, combined medication is often needed. The commonly used combination scheme is: statins plus fenofibrate or statins plus nicotinic acid, but the combination of drugs often aggravates the adverse reactions of patients, especially the damage to the liver. Because Jiangzhi Tongluo Soft Capsule has clear lipid-regulating effect and unique liver-protecting effect, clinicians have another choice in treating hyperlipidemia, especially patients with abnormal liver function.
In a word, Chinese medicine has its own unique advantages in reducing blood fat and protecting liver, improving hyperlipidemia symptoms and protecting cardiovascular and cerebrovascular diseases. Zhibitai capsule can reduce blood lipid and improve dizziness, chest tightness, abdominal distension, loss of appetite, mental fatigue and other symptoms. Jiangzhi Tongluo Soft Capsule can not only reduce blood lipid, but also improve chest pain, precordial tingling, chest tightness and other symptoms. According to the actual situation, it can be used dialectically.