Lee's reaction is an organic chemical reaction, which is usually used to synthesize phenol or its derivatives. The reaction principle is that nitro compounds react with reducing agents under strong alkali conditions, and then the generated nitroso compounds are further reduced to imine compounds and finally converted to phenol. This chemical reaction can be used to synthesize phenol and its derivatives on a large scale, and is widely used in medicine, dyes, spices and other fields.

Lee's reaction is an important organic chemical reaction because it can synthesize phenol and many organic compounds. Lee's reaction is widely used in the production of drugs, dyes, spices and other chemicals. For example, it can be used to synthesize medical synthetic materials, coal tar, dye auxiliaries, etc. In addition, Lee's reaction is widely used in chemistry because of its mild reaction conditions, short reaction time and high synthesis yield.

At present, with the deepening of organic chemistry research and the continuous updating of technology, Lee's reaction is also developing and perfecting. Among them, the yield and reaction efficiency can be improved by changing factors such as catalyst, reaction medium, temperature, pressure, reactant type and ratio. In addition, the study of Lee's reaction is closely combined with environmental protection, and some green chemical reactions have been designed and developed, realizing the principles of environmental friendliness, safety and reliability. In the future, the application of Lee's reaction will be more extensive, because it plays an important role in various fields.