Efficacy and indications of Poria cocos;

(A) the role of Poria cocos

Diuretic action

Poria cocos is used for dysuria and edema. Poria cocos has the function of promoting diuresis and eliminating dampness, but it is mild in nature, promoting diuresis without damaging vital qi, and is an important drug for promoting diuresis and eliminating dampness. All the symptoms of dysuria and stagnant water and dampness, regardless of cold and dampness, damp and heat, or spleen deficiency and dampness accumulation, can be used together. For cold and dampness, it can be combined with Guizhi and Baizhu. For damp-heat, it can be combined with Polyporus and Alisma orientalis. For spleen-qi deficiency, it can be combined with Dangshen, Huangqi and Atractylodes macrocephala. For deficiency cold, it can also be used with aconite and Atractylodes macrocephala.

Antibiotic action

Poria cocos decoction 100% plate drilling method has inhibitory effect on Staphylococcus aureus, Escherichia coli and Proteus.

Effect on digestive system

Poria cocos has a direct relaxing effect on isolated intestine of rabbits, a preventive effect on ulcer caused by pyloric ligation in rats, and can reduce gastric acid. In addition, it has obvious protective effect on liver injury induced by carbon tetrachloride in rats, significantly reducing the activity of alanine aminotransferase and preventing hepatocyte necrosis.

reduce the blood sugar

Poria cocos can lower blood sugar. Poria cocos has a certain therapeutic effect on people with hyperglycemia.

Effects on the heart

Chinese medicine believes that Poria cocos can be used for palpitation, insomnia and other diseases. Poria cocos can nourish the heart and soothe the nerves, so it can be used for anxiety, palpitation and insomnia. It is often combined with ginseng, polygala tenuifolia and Ziziphus jujuba seed.

The experiment also shows that tincture and immersion liquid have inhibitory effect on isolated toad heart, and ether or ethanol extract can enhance cardiac contraction. It has no antiemetic effect on pigeon vomiting caused by digitalis.

Antitumor effect

Poria cocos polysaccharide has a strong anti-tumor effect in animal experiments. Poria cocos has the effects of resisting thymus atrophy, spleen enlargement and tumor growth.

Effect on immune function

(1) increased the cytotoxicity of macrophages.

(2) Hydroxymethyl pachyman can obviously increase the number of antibody secreting cells and specific antigen binding cells in the spleen of mice.

(3) Increase the number of acid nonspecific esterase positive lymphocytes.

(4) Enhance the cytotoxicity of T lymphocytes.

Effect on blood system

Poria cocos can accelerate the recovery of leukopenia, increase the red blood cells of healthy people by about 25% in vitro, and effectively delay the depletion of blood cells during incubation. The experiment shows that Poria cocos can significantly increase plasma corticosterone in mice.

Effect on central nervous system

Fuling decoction has sedative effect. Synergistic effect of poria cocos and pentobarbital sodium. Fuling decoction (10g/kg) failed to significantly prolong the anesthesia time of pentobarbital sodium. When the dose was 40g/kg, the anesthesia time was significantly longer than that of the control group, and the sedation index increased with the increase of dose. This synergistic effect may be caused by their central inhibition, and may also hinder the decomposition and excretion of pentobarbital, leading to prolonged anesthesia time.

be anticancer

Poria cocos has certain anticancer effect. Clinically, esophageal cancer, gastric cancer, liver cancer, nasopharyngeal cancer, tongue cancer, breast cancer, bladder cancer, lung cancer, ulcerative melanoma and other cancers are all patients with spleen deficiency and dampness, phlegm retention and damp-heat stasis.

Yiqi Jianpi

Chinese medicine believes that Poria cocos can be used for diarrhea due to spleen deficiency. Poria cocos can not only strengthen the spleen, but also ooze moisture. For diarrhea and leukorrhagia caused by spleen deficiency, Poria has the effect of treating both the symptoms and root causes, and is often used with Dangshen, Atractylodes macrocephala and Yam. It can also be used as an auxiliary drug for tonifying lung and spleen and treating qi deficiency.

Treating phlegm

Poria cocos is used for cough due to phlegm retention, phlegm dampness entering collaterals, and shoulder and back pain. Poria cocos has a therapeutic effect on spleen deficiency, which can not transport water and dampness, stop aggregation and produce phlegm. Pinellia ternata and Chenpi can be used together, or together with Guizhi and Atractylodis Rhizoma. For phlegm-dampness entering collaterals, sore shoulder and backache, it can be combined with Banxia and Fructus Aurantii.

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