Sjogren's syndrome (ss), also called autoimmune exocrine epithelial cell inflammation or autoimmune exocrine gland disease, is a chronic inflammatory autoimmune disease mainly involving exocrine glands. Clinically, besides the dysfunction of salivary gland and lacrimal gland, there are symptoms of dry mouth and dry eye, which involve other exocrine glands and other organs outside glands, resulting in multiple system damage. There are many autoantibodies and high immunoglobulin in its serum. Diseases are divided into primary and secondary.

Qudu Qingrun Decoction is a pure Chinese medicine preparation. According to the dialectical treatment of TCM theory, according to the main physiological functions of the five internal organs, they are biochemistry and storage of essence, qi, blood, body fluid, spirit, heart controlling blood vessels, liver controlling drainage, spleen controlling transport and transformation, lung controlling qi, and kidney storing essence controlling water, which fundamentally treats dryness syndrome in regulating human body's water and fluid metabolism.