Thin and dry eyes, exophthalmos, frightened appearance, excitement and anxiety are more common in hyperthyroidism face; Dark complexion, purple cheeks, slightly cyanotic lips, more common in the mitral valve surface; A wry smile can be seen in tetanus; Typhoid fever is a state of indifference, unresponsiveness and no desire. The manifestations of chronic diseases are haggard, dim or pale face and dim eyes. It is found in chronic consumptive diseases, such as malignant tumor, liver cirrhosis and severe pulmonary tuberculosis.