The slimming mechanism of orlistat (1) is a direct mechanism: orlistat can inhibit the activity of gastropancreatic lipase, directly block the absorption of fat in food, and reduce the intake of calories and fat. Once the intake is less than the consumption, the body fat will naturally decrease, thus achieving the purpose of losing weight;
(2) Indirect mechanism: Orlistat can reduce postprandial blood lipid concentration and relieve insulin resistance of patients, thus further reducing blood lipid, blood sugar, blood pressure and body weight.
Who recommends taking orlistat? At present, the suggestion put forward by the American Endocrine Association is that the condition for taking diet pills is that the body mass index (BMI) is ≥ 27 kg/m? And at least one obesity-related complication (such as diabetes and hypertension). ) or body mass index ≥30kg/m? .
However, at present, the indications for using this drug at home and abroad are wide, and the body mass index ≥24kg/m? Friends can use it.
Who is forbidden to take it? ① pregnant women; ② those who are allergic to drugs; ③ Chronic malabsorption syndrome and cholestasis; ④ Patients with organic obesity (such as hypothyroidism).
Precautions for taking orlistat (1) During taking orlistat, there may be increased gastrointestinal exhaust, urgent defecation, fatty (oily) stool, and gastrointestinal discomfort;
(2) There are more and more reports of liver injury caused by orlistat, so friends with poor liver function must check their liver function in time;
(3) Orlistat will affect the absorption of vitamins A, D and E, so these vitamins should be supplemented in time during medication.
Osetide, as an auxiliary weight-loss drug, has limited effect after all. Therefore, while adhering to the scientific way of losing weight, we must keep our mouths shut and open our legs in life.