No. The crescent-shaped blackening of nails is caused by hyperemia or subcutaneous hemorrhage. Compound glycyrrhizin capsule is a prescription drug, which has immunomodulatory, antiallergic and anti-inflammatory effects. It is mainly used to treat chronic liver disease and improve symptoms such as abnormal liver function. Therefore, taking compound glycyrrhizin capsules will not lead to crescent-shaped blackening of nails.