Of course it's harmful. Drinking cola often will cause calcium loss, spermicide, bad for teeth and easy to get fat. Drinking more coffee is more harmful! Disadvantages of coffee: 1. Caffeine supplementation helps to improve your alertness, sensitivity, memory and attention when you are nervous. But if you drink more coffee than you are used to, you will have the same dose of stimulants, which will cause tension. For people with anxiety tendency, caffeine can aggravate the symptoms of sweating, palpitation and tinnitus. 2. Caffeine, which aggravates hypertension, is often combined with other simple painkillers because of its analgesic effect. However, if you take a lot of caffeine for a long time, if you already have high blood pressure, using a lot of caffeine will only make your situation worse. Because caffeine alone can raise blood pressure, if combined with emotional tension, it will have a dangerous multiplier effect. Therefore, people at risk of hypertension should especially avoid drinking caffeinated drinks when working pressure is high. Some people who drink coffee all the year round think they are immune to the effects of caffeine, but this is not the case. A study shows that after drinking a cup of coffee, the blood pressure can rise for as long as 12 hours. 3. Caffeine inducing osteoporosis has a good diuretic effect. If you drink a lot of coffee for a long time, it will easily lead to bone loss and adversely affect the preservation of bone mass. For women, it may increase the threat of osteoporosis. However, the premise is that people who usually have insufficient calcium intake in food, or people who don't exercise often, and postmenopausal women, due to insufficient estrogen, calcium loss, coupled with a large amount of caffeine, may pose a threat to bones. If you can enjoy it in a reasonable amount, you can still do it without choking. In addition, the following six kinds of people should not drink coffee: suffering from hypertension, coronary heart disease, arteriosclerosis and other diseases-drinking coffee for a long time or in large quantities will cause cardiovascular diseases. Older women-coffee can reduce calcium and cause osteoporosis. After menopause, women need to supplement ten times as much calcium every day. Patients with stomach trouble-drinking too much coffee will make stomach trouble worse. Pregnant women-drinking too much coffee can lead to fetal malformation or miscarriage. Cancer patients-drinking too much coffee is dangerous for normal people.