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Aspirin is best taken on an empty stomach.
It is best to take aspirin orally on an empty stomach in the morning. Because it is aspirin enteric-coated tablets. Enteric-coated tablets usually do not disintegrate in gastric juice, but only disintegrate in intestinal juice and are absorbed. It usually has an enteric coating on the outer bread of ordinary tablets. Aspirin can directly damage the gastric mucosa, make the epithelial layer of mucosa lose its integrity, decompose the mucus layer, and thus destroy the gastric mucosal barrier. Aspirin enteric-coated tablets should not be broken, chewed or ground into powder when taken orally, but should be swallowed whole.