Market price of Qumei: 285 yuan/box (10mg*30s). General monthly consumption: 1 box (please follow the doctor's advice).

Manufacturer: Taiji Group

Ingredients: 5- hydroxytryptamine and norepinephrine uptake inhibitor.

Qumei weight loss principle:

Burning fat: increase the energy consumption of brown cells by inhibiting the intake of norepinephrine.

Speed up the metabolism of fat.

Control calorie intake: By inhibiting 5-HT reuptake, people can reduce hunger.

Physical and chemical characteristics of Qumei

The molecular formula is C 17H26CIN-ACI. H20 (product description: white crystal, solubility 2.9mg/m/lph=5.2).

Pharmacokinetic index

Tmax (prototype) =1.2ht1/2 =11h.

tmax(M 1、M2)= 2.5-3.6h t 1/2 = 14- 19h

The main excretory route is the kidney (77%)

The peak time of blood drug concentration is relatively short, but the elimination time is relatively long. Taking medicine once a day can ensure the effective blood drug concentration.

Usage and dosage of Qumei

The recommended starting dose is 10mg once a day, which can be taken alone or with food in the morning. If the weight loss is insufficient, the dose can be adjusted to 15mg per day after 4 weeks. If the patient cannot tolerate the dose of 10mg, it can be reduced to 5mg. Dose should be adjusted according to the patient's blood pressure and heart rate. Doses exceeding15mg/day are not recommended.

Suitable for people-simple obesity

Simple obesity (nutritional obesity)

The following people should not bring Qumei:

1, patients treated with monoamine oxidase inhibitor (MAOI);

2. anorexia nervosa;

3. Pathological obesity: such as Cushing's syndrome and hypothyroidism;

4. Hypertensive patients with uncontrolled and poorly controlled blood pressure, patients with coronary heart disease, heart failure, arrhythmia and stroke;

5. Patients with severe liver and renal insufficiency;

6. Pregnant, lactating and pregnant women;

7.1children under 6 years old and elderly people over 65 years old are not recommended;

8. People who are allergic to this product.

The following people should use Qumei with caution:

1, patients receiving 5-HT drugs;

2. Patients taking drugs containing norephedrine, ephedrine and pseudoephedrine;

4. Patients with high myopia and retinal detachment;

5. Patients with cholelithiasis;

6. Patients with angle-closure glaucoma;

7. Those with a history of epilepsy;

8. Patients with menstrual disorders.

Suggestions when combined with some drugs:

1. The following drugs cannot be taken with trimetazidine at the same time, and can only be taken two weeks after stopping using them. Similarly, the following drugs can only be taken after two weeks of stopping trimetazidine:

1) monoamine oxidase inhibitors: phenelzine, propargyl amphetamine, etc.

2)5- hydroxytryptamine drugs: phenoxypropylamine, trifluroxime, florfenicol, sertraline, venlafaxine, etc.

3) Selective serotonin reuptake inhibitors or some drugs for treating migraine: succinate, dihydroergotamine, hexamethylenetetramine dextran, Demerol, serotonin, fentanyl, lithium preparation or tryptophan;

4) Central appetite suppressants: Fenfluramine, Moindor, etc.

2. Be careful when using the following drugs at the same time, and it must be carried out under the guidance of a doctor. We suggest that it is best not to use it together with trimethoprim: phenylpropanolamine, ephedrine and pseudoephedrine.

3. When the following drugs are combined with trimethoprim, it is necessary to carefully observe the physical changes and consult a doctor at any time if necessary: ketoconazole and erythromycin.

4. It is recommended not to consume too much alcohol when taking trimethoprim.

Adverse reactions of Qumei and others

Any drug has adverse reactions. The FDA of the United States and CPMP of Europe have strict regulations on adverse drug reactions, requiring that any drug instructions should put the protection of patients' health first. For example, any adverse reactions that may be caused by drugs in clinical trials or whether they are related to drugs are unclear, they should be included in the instructions or explained, even if there is only one case; People who may have poor curative effect or are not suitable for drug treatment should be taken into consideration. These regulations are measures taken to fully protect consumers' personal rights, rational consumption rights and physical health, and have become the general standards for formulating drug instructions in developed countries.

The directions of Qumei, including adverse reactions, were translated from the original American instructions, and it was one of the earliest drug instructions made in China with reference to international general standards (including FDA standards). This is of great significance to standardize China's drug instructions and gradually connect with the international community, and its significance exceeds the drug instructions themselves. At the same time, it shows the scientific and safety of the drug more powerfully, and will be gradually popularized in a new batch of drugs in the future.

Most of the adverse reactions of tramadol are mild. According to the pharmacological and therapeutic effects of this product, it usually appears within 4 weeks after taking the medicine and lasts for about one week. A few people last a little longer, more common in dry mouth or satiety. There is no need to stop taking medicine when these phenomena occur, and these phenomena disappear naturally with the extension of medication time.

Adverse reactions of various systems are also listed in Qumei's instructions. These adverse reactions rarely occur in domestic clinical trials for half a year, and the most serious adverse reactions (such as interstitial nephritis, tracheitis, dyspnea, etc. ) did not happen.

In order to protect consumers' rational consumption rights, correctly understand and treat the adverse reactions of Qumei instructions, and take this product with confidence, it is hereby declared.