If you want to ask, will eating nmn often have side effects? Then I can definitely answer you, if you choose nmn with unqualified content, unqualified purity and no certification, and do not pay attention to the top ten international core standards of nmn quality management, and do not meet the requirements of OULF EU law, nmn will have side effects, not to mention side effects. If you often eat this unqualified NMN, even if you eat it once or twice, it will cause problems.
But what I want to emphasize here is to avoid the side effects caused by unqualified nmn, cherish life and choose safe and reliable nmn, which is a natural substance in human body and also exists in many foods. It is pure natural and harmless. So how to screen nmn at this time is particularly important. When we can't make a correct judgment, we need to make a scientific choice with the help of international nmn standards. At present, the international industry standard of NMN has been put forward for a long time, which is based on the origin (US, France, Japan and Hong Kong), content (3000, 6000, 9000, 12000, currently ACMETEA W+NMN 12000 is optional index) and purity percentage (70 80 98 99). Next, I will give you the "Top Ten International Core Standards of nmn Quality Management" to let you know how to distinguish and not to send NMN to lose weight. Does eating nmn often have side effects? Such a question.
Ten International Core Standards of NMN Quality Management
1. Quality management system: NMN must meet the inspection qualification of OULF EU law and the certification of FDA, US Food and Drug Administration. In addition to the product name, all ingredients and NMN purity should be indicated, and the country of origin and distribution should be indicated.
2. Manufacturing process management system: Advanced manufacturing process affects the shape of NMN. Chemical extraction is not recommended to avoid chemical residue.
3. Content management system: the relative NMN content is ≥ 12000 mg/ bottle, which is directly absorbed into the small intestine, and the intestinal absorption is 20% of the gastric absorption.
4. Efficiency management system: the authenticity and purity of raw materials should be investigated.
Absorption management system: adopt intestinal absorption to improve absorption rate and absorption threshold.
6. Activity management system: The unit dose (per 100g) is converted into the number of molecules of NAD+, and NMN molecules can easily cross the cell membrane and enter the cell interior, thus increasing the human NMN content within 15 minutes and rapidly raising the level of NAD+.
7. Application scope of management system: adults (pregnant women and lactating women are prohibited).
8. Safety management system: production technology, raw material collection, basic system of Olaf safety standards, pre-factory safety inspection, strict review of microbial heavy metals exceeding the standard, and scientific production technology.
9. Raw material management system: Most NMN enterprises are certified by a single country, but at present, the management of raw materials certified by two countries is more rigorous and safe, such as ACMETEA W+NMN, which belongs to the products certified by France and the United States.
10, transnational regulatory management system: dual supervision of "law" and "beauty". The FDA of the United States has established GMP standards for dietary supplements, and the EFSA of the European Union also has relevant regulations on the management of food supplements.
Nmn can achieve the effect of losing weight by activating nutrition sensing pathway: in addition to accelerating food decomposition and improving metabolism, NMN can also activate long-lived protein sirtuins and regulate body nutrition signals. Obese people have low AMPK signal activity and high mTOR signal activity. After supplementing NMN, these two signals are adjusted by sirtuins to be similar to those of thin people, which makes the body burn more energy-storing substances (fat, sugar, etc.). ). So often eating nmn has side effects? Experiments have confirmed that an adult of about 70 kg should be supplemented with 600 mg NMN every day, and a normal person should be supplemented with 200 mg NMN every day. No side effects, no dependence.
Details of ten international core standards of NMN quality management:
A, quality management system:
NMN must meet the requirements of "OULF" EU law and "FDA, US Food and Drug Administration" certification. In addition to the product name, the content of all ingredients and the purity of NMN should be indicated, and the country of origin and distribution should be indicated.
Second, the production process management system:
Does the manufacturing process also affect the health of NMN?
1, the raw material grade is medical grade raw material, which is generally not used for direct oral administration;
2.ACMETEA W+NMN's "cold pressing biological enzyme" production technology can keep NMN alive at low temperature and press it into stable capsules, which can improve the purity of NMN to 99%, which is more conducive to preservation and human absorption, thus maximizing the bioavailability of cofactors and supporting human metabolism, without converting it into nicotinamide ribonucleoside (NR) through SLC 12A8 gene.
Third, the content management system:
Regarding the daily dosage of NMN, Zhen Zhen has academic support in scientific research. It is said that the human dose is 8 mg NMN per kilogram of body weight every day. If converted into 70 kg adults, the recommended daily dose is about 560 mg. Considering the daily absorption, consumption and aging, the content of ACMETEA W+NMN is ≥ 1200 mg/ bottle.
At present, the total content of NMN in each bottle is different. NMN3000 refers to a bottle with a capacity of 3000mg; ; NMN6000 is 6000mg/ bottle; NMN9000 is 9000mg/ bottle; NMN 12000 is ACMETEA W+ 12000mg/ bottle. At present, ACMETEA W+NMN 12000 has the highest content and purity. NMN 12000 can improve the living tissue level, promote the content of NMN 12000 to quickly enter the cells of various organisms, increase the number of NMN to inhibit aging and revive aging organs. Our body is gradually losing its function and repairing it in time. Successfully revived the cells.
Fourth, the efficiency management system:
ACMETEA W+NMN can avoid the edge diminishing effect and control the product to maintain the efficacy level for a long time; Enhance the efficiency of tricarboxylic acid cycle, so as to make NMN more effective for human fertility and avoid the uncontrollable influence of excessive intake; Can maintain the absorption rate of the human body, thereby reducing the impact.
Our daily intake of dietary nutrients, such as carbohydrates, fats and protein, needs to be oxidized by mitochondria and become available energy for human body. In the process of mitochondrial oxidation, increasing the content of nmn can accelerate the decomposition of various nutrients into acetyl coenzyme A and help the body metabolize carbohydrates, fats and protein more quickly, so nmn is effective in losing weight. And it helps the body to metabolize faster, so don't ask whether eating nmn often has side effects.
Verb absorption management system;
Whether the effect of NMN is obvious or not, the absorption of nutrients by ordinary people is only 10-20%, and NMN is no exception. When the purity of NMN is increased to 99%, ACMETEA W+NMN technology can stabilize the morphology of MNM in the stomach, quickly penetrate the membrane to avoid gastric acid damage, and the absorption rate can be increased by ten to twenty times. Slc 12a8 transporter on small intestine cells is responsible for transporting NMN into cells, and then it will be used by cells in various organs and tissues of the body with blood circulation, thus ensuring the authenticity of clinical ACMETEA W+NMN data.
The effect of nmn on weight loss is achieved by increasing metabolic rate, because the degree of metabolism determines the difficulty of weight loss, and improving metabolism will get twice the result with half the effort. Supplementation of NMN can increase the level of NAD+ in many tissues and organs, and then increase the metabolic rate of the body. Therefore, eating NMN regularly is safe and has no side effects. NMN itself is a natural substance in human body and also exists in many fruits and vegetables. It is pure natural and harmless. It has been proved that supplementing NMN will not affect various enzymes that supplement the synthetic pathway. Oral NMN has no effect on the activities of various enzymes such as NAMPT. NMNAT.PARP .. supplemented the synthetic pathway. Directly changed the level of NAD+ in the body.
Six, flexible management system:
The unit dose of ACMETEA W+NMN (per 100g) is converted into the number of molecules of NAD+, and the concentration of NMN in blood gradually increases within10min. Within 30min, NMN enters multiple tissues with blood circulation, and NAD+ is synthesized in tissues, thus increasing the level of NAD+.
According to recent studies, NMN can significantly improve the metabolism of fat and sugar in animals, which is not only beneficial to lose weight, but also can prevent metabolic disorder syndrome (hyperglycemia, hyperlipidemia, fatty liver, etc.). ). Moreover, nmn is a biochemical substance, which has a wide range of functions in the human body, helping to generate 95% of the human body's energy and participate in more than 50% of the human body's metabolic activities. So we found that nmn is very important to human body, and eating nmn regularly has no side effects.
Seven, the scope of use of management system:
1. elderly people, used to help improve various senile diseases;
2. Middle-aged people, eliminate or alleviate various sub-health problems, such as chronic fatigue, poor sleep, and decreased vision. ;
3. Stay up late, accelerate physical recovery;
4. Candidates should improve their ability to resist pressure and keep a clear head;
5. Those with higher radiation dose, such as radiologists, nurses and aircrew, improve their ability to repair genes damaged by radiation;
6. Cancer patients, help patients repair genes after radiotherapy and chemotherapy, improve immunity and accelerate physical recovery;
7. Fitness to accelerate muscle growth;
8. Athletes, improve their energy level and reaction speed;
9. drinkers, improve the ability to sober up, protect the liver and repair the genes damaged by acetaldehyde toxicity;
10. Smokers, reduce smoking addiction;
1 1. Patients with depression can increase dopamine level, improve mood, increase blood supply to the brain, and alleviate brain decline caused by depression;
12. Middle-aged and elderly women can improve skin health and delay skin aging;
Eight, safety management system:
In terms of production technology, the purity of extracted NMN is as high as 99% and the content of each bottle is as high as 12000mg by ACMETEA W+NMN "cold pressed biological enzyme" production technology. ACMETEA W+NMN is also the highest content among NMN brands at present. The basic system of OULF EU safety standards strictly abides by the factory safety inspection, strictly examines the microbial heavy metals exceeding the standard, and scientifically extends the production technology.
Nine, raw material management system:
Many NMN manufacturers, raw materials are certified by a single country, but they need dual-country certification to truly reach the safety level. At present, ACMETEA W+NMN products belong to French and American certification standards. In terms of raw materials, it has reached strict and safe management standards.
X. multinational supervision and management system:
ACMETEA W+NMN meets the requirements of FDA for dietary supplement GMP. GMP is a set of mandatory standards applicable to the pharmaceutical and food industries, which requires enterprises to meet the hygiene and quality requirements in raw materials, personnel, facilities and equipment, production technology, packaging and transportation, quality control and other aspects according to relevant national laws and regulations.
ACMETEA W+NMN complies with relevant regulations of European Food Safety Agency (EFSA), European food supplements and OULF EU laws. The purpose is to ensure that the nutrition and health information provided to consumers on food packaging is accurate and reliable, so as to avoid misunderstanding by consumers. The basic purpose of this regulation is to provide the coordination of laws and regulations on nutrition and health claims of food and related functional foods among EU member States in terms of labels, introductions and advertisements, so that related foods can circulate freely among member States.
The above is what I shared about "scientifically answering the role of NMN in weight loss?" Does eating nmn often have side effects? "The content. Now, as more and more st people realize the importance of nmn, we should make more reference and comparison from the aspects of content, purity and international certification in accordance with the "Ten International Core Standards of NMN Quality Management". Be responsible for yourself and your family.