After eating food containing tyramine, such as broad bean, lentil, banana, chocolate, beer, wine, cheese and pickled fish, tyramine is metabolized by monoamine oxidase in the body. But if you take monoamine oxidase inhibitors at the same time, such as paganin (You Jiangning), phenelzine, and furazolidone, etc. (Although these are all western medicines, many Chinese medicines may contain ingredients similar to the above medicines), tyramine contained in food is difficult to decompose, which will cause sympathetic nerve excitement and serious reactions such as hypertensive crisis after accumulation.

The ingredients contained in the daily diet are quite complex, which may change the absorption and metabolism of drugs in the body and reduce or increase the absorption of drugs. For example, a high-fat diet helps to promote the absorption of fat-soluble drugs, such as fat-soluble vitamins A, D, E and so on. And its absorption can be increased after eating fat and meat. Medical research has confirmed that vegetable oil can promote the metabolism of some drugs in the body and shorten the duration of drug action.

High protein diet can also enhance the activity of liver drug enzymes and enhance the toxicity of drugs and their metabolites. A high-protein and high-fat diet can lead to acidic urine. At this time, if you take weak acid drugs such as tetracycline, because of its high fat solubility, the degree of dissociation in acidic urine is small, resulting in reduced excretion, increased blood drug concentration and enhanced curative effect. If people eat vegetables instead of meat, alkaline urine will appear, and if they take weak alkaline drugs such as gentamicin, their efficacy will be enhanced.

Some sweet drinks make people's digestive juice acidic, especially if they are drunk too much, which will reduce the absorption of antihypertensive drugs such as reserpine, atropine and ephedrine, thus weakening the efficacy. On the other hand, if you drink a lot of alkaline drinks such as carbonated water when taking the above drugs, the digestive juice in your stomach will be alkaline, which will increase the absorption of the above drugs, and toxic and side effects may occur when taking them in large doses.

People who eat a high-salt diet have a large intake of sodium, which is easy to cause sodium retention in the body. Long-term high sodium state will cause electrolyte imbalance in the body, interfere with the normal metabolism of some drugs, and make them unable to exert their normal curative effects.