"The above three points complement each other. If the transplanted blastocyst gene is abnormal, there will be aborted, premature or deformed children, so how can there be healthy babies? It is also useless to carry out gene detection on blastocysts with stable morphology and structure, but to carry out gene detection on blastocysts whose activity and genetic material are easily affected and destroyed during the detection process. If there is no exclusive program to provide high-quality sperm and eggs for bursa of fabricius, the availability rate of blastocysts is not high. " Dream beauty HRC experts said.
In fact, according to the answer of American dream beauty HRC experts, it can be summarized as: healthy baby = exclusive treatment plan+blastocyst culture +PGS/PGD gene detection. The following is a detailed interpretation from three aspects: scheme, baby bag and genetic testing:
Exclusive treatment plan (the right medicine)
The so-called exclusive treatment scheme is that doctors prescribe the right medicine for patients at different stages of IVF cycle and formulate corresponding IVF auxiliary schemes:
Before ovulation induction, Mengmei HRC experts will choose the appropriate ovulation induction scheme according to the patient's physical condition. If the patient is old, the ovarian reserve function declines and the conventional ovarian reserve declines, he will be advised to use micro-promotion to obtain higher quality eggs;
During ovulation induction, experts will also dynamically monitor the development of follicles through B-ultrasound at different times to understand the growth rate of follicles and the response of ovaries to drugs, and adjust the dosage in time to avoid ascites, edema and ovarian overstimulation caused by drug overdose.
In embryo transfer, because the previous drugs will affect the growth of endometrium and the endocrine level of the body, before blastocyst transfer, the patient's physical condition will be checked and monitored in real time to determine the best transfer time.
Everyone who does IVF should have their own treatment plan to ensure the success rate of IVF on the premise of ensuring the health and safety of mother and baby and saving time, effort and money to the maximum extent. Therefore, it is particularly important to cooperate with the doctor to do the relevant physical examination before going to the United States to do IVF.
Blastocyst culture (the source of life)
There are two methods to cultivate fertilized eggs in clinic. One is to culture them to form early embryos of 8~ 12 cells on the third day; Second, on the fifth day, blastocysts composed of 100 cells were formed. The reason why patients are advised to choose to cultivate fertilized eggs until the fifth day is mainly because blastocysts have strong advantages in both implantation ability and development potential. The reason for this is the following：
1. Blastocyst culture is a natural screening process. Embryos with strong vitality and great development potential will grow into blastocysts, while those with poor quality, inferior quality or seemingly transplantable embryos will be naturally eliminated. So the embryo implantation rate of blastocyst culture test will be higher.
2. Under normal circumstances, the early embryos implanted in the maternal uterine cavity will swim in the uterine cavity and even swim into the fallopian tube until they grow into blastocysts and contact with the endometrium after 2~3 days. If the proximal end of female double fallopian tubes is blocked, the intrauterine environment is not suitable for the continued growth and development of early embryos, which will lead to the failure of embryo implantation; If the fallopian tube is not completely blocked due to inflammation, or abnormal hormone secretion makes the fallopian tube peristalsis not smooth, the possibility of ectopic pregnancy will be higher. However, the implantation of blastocyst in uterine cavity is just in synchronization with endometrium, and the success rate of implantation will also be improved.
3. There are a large number of blastocysts, and the differentiation of inner and outer peripheral cells is obvious, which is very beneficial for American cute HRC reproductive experts to accurately extract multiple peripheral cells, which makes gene detection more accurate and does not damage the quality of blastocysts.
Therefore, if you want to have a healthy baby, blastocyst is the best source of life.
PGS/PGD gene detection (gene optimization)
Genetic testing is an important part of IVF in the United States, because even vigorous blastocysts have chromosomal abnormalities and genetic diseases. PGS/PGD gene detection is the core technology of the third generation IVF technology, which mainly consists of PGS gene screening and PGD gene diagnosis:
PGS: comprehensively detect the number and structure of 23 pairs of chromosomes in blastocysts, and compare and analyze the logarithm and morphological structure of chromosomes to screen out abnormal blastocysts and improve the pregnancy rate in vitro;
PGD: To detect whether blastocysts screened by PGS carry genes with genetic defects (or gene mutations that may cause specific diseases) to prevent the birth of deformed children.
It is reported that American Dream Beauty HRC has 40,000+China families, and the dream of having a healthy baby has been realized with the help of the third-generation IVF technology.
This article is transferred from American Dream Beauty HRC official website.