Studies have proved that "nattokinase" is the strongest thrombolytic enzyme in about 230 kinds of food in the world. Nattokinase is a biological enzyme extracted from fermented soybean. 1985, Professor Nishimoto of Japan discovered the potent thrombolytic effect of nattokinase, which set off a worldwide upsurge of research and application of nattokinase. The International Thrombosis Federation (ITA) announced that it is convinced that long-term consumption of natto is one of the main reasons for Japanese longevity. The advantage of thrombolysis is persistence. Urokinase and lumbrokinase are commonly used thrombolytic agents in clinic, which can only be intravenous drip. No matter which one is injected into the blood, the action time (half-life) is very short, only 4-20 minutes. Nattokinase can be taken orally, and its action time in the body can be as long as 8- 12 hours. The thrombolytic activity of nattokinase in vivo is 19 times that of fibrinolytic enzyme, and it is a kind of protein whose molecular weight is much smaller than that of UK, SK and tPA, which can be absorbed by intestinal tract. The thrombolytic properties of nattokinase in vivo and in vitro have also been confirmed by experiments. It has a rapid and long-lasting effect in vivo, and can also activate tPA in vivo to moderately and continuously improve the fibrinolytic activity of blood.