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Why do mice get fat after eating oil, but people don't?
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I have been trying and advocating a low-carbon and high-fat (ketogenic) diet for a long time. Personally, I have a deep understanding. Up to now, I am not only getting healthier, but also having a better attitude. At the same time, I also saw countless netizens who lost weight with me and even reversed diabetes. I had a good time along the way. (randomly intercept 2 messages from netizens)

(User message, slimming success)

(User message, diabetes has been reversed)

Just when I was full of motivation for everyone's change, someone questioned: "Skinny dragon, skinny dragon, foreign research shows that rats will become fat after eating a diet with high fat and low carbohydrate, and they are insulin resistant ...".

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Under normal circumstances, I will accept questions, because everyone's cognition will be different because of different physical conditions and different concepts.

However, in view of this, I must investigate it thoroughly. If I want to die, I must find out why rats will gain weight by feeding them a high-fat and low-carbon diet.

Study on feeding obese mice with high-fat feed

I don't know if I don't know, but I was shocked to find that 35 papers and related research involved feeding rats a high-fat diet.

But only five of them gave the diet ratio, such as how much sugar and fat they ate, but most of them didn't mention what sugar and fat they fed the mice.

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Only two studies have given specific data with reference significance:

Study 1

From Melbourne University, let's take a look at its details first.

The researchers provided 65,438+07 mice with a standard diet for six weeks, including 20% protein, 70% carbohydrate and 65,438+00% fat.

After 6 weeks, 9 mice were divided into the first group and 8 mice were divided into the second group.

The first group: 9 mice were fed a low-carbon and high-fat diet for 9 weeks, namely 13% protein, 6% carbohydrate and 8 1% fat.

The second group: adhere to the standard diet for 9 weeks, that is, 20% protein, 70% carbohydrate, 10% fat.

Later, it was found that the mice in the low-carbon and high-fat diet group gained weight, had insufficient glucose tolerance and increased insulin levels.

They gained about 15% body weight on average, and their body fat increased from 2% to 4%.

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Study 2

From the University of California, Santa Barbara and Sanford-burnham Medical College.

After feeding mice a high-fat and low-carbon diet for a period of time, researchers found that mice's cells could not perceive blood sugar and respond, and eventually developed type 2 diabetes.

These two studies are well-founded, which goes against the traditional idea that a low-fat diet is healthier for many years. With the amulet, some people even say that a high-fat diet will lead to diabetes.

There are huge loopholes in this research.

After reading it, I am also at a loss. No, obviously fat has no effect on blood sugar. Why do mice get diabetes? Did they eat something they shouldn't?

Then I found more information and more in-depth research details, and then I suddenly realized that we only saw the surface. In fact, foreign medical experts and nutrition experts have made many comments on the unprofessional degree of these two studies:

Research loopholes

Food sources being studied

Let's see what the researchers let the mice in the high-fat and low-carbon group eat:

(Dietary content of high-fat and low-carbon group)

At first glance, it seems not bad. Careful analysis, it is wrong.

First of all, in the high-fat, low-carbon group, carbohydrates actually come entirely from refined sugar, which is staggering.

Ironically, the carbohydrates of mice in the low-fat standard diet group basically have no refined sugar, and most of them come from wheat.

In a real high-fat and low-carbon diet, the recommended carbohydrate source is foods with high dietary fiber content that are beneficial to the human stomach, such as lettuce, broccoli and Chinese cabbage, instead of taking two bites of a can of sugar like mice in the high-fat and low-carbon group.

I have always stressed that sugar and fat are more terrible together.

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In addition, the sources of fat, cocoa butter, low erucic rapeseed oil and ghee, are mostly refined.

Cocoa butter and ghee are not a big problem, but they are generally not the main sources of fat intake. There are still some problems with rapeseed oil. I also wrote in this article that rapeseed oil may make you a little fatter.

A strict low-carbon ketogenic diet suggests eating healthier fats, such as coconut oil, lard, olive oil and grass-fed butter, rather than unhealthy oils that can cause various inflammations and diseases, such as soybean oil and rapeseed oil.

The source of protein is casein.

Casein extracted from dairy products is an antigenic protein, which is easy to cause indigestion. It is not directly recommended in any high-fat and low-carbon diet of human beings.

Our common recommended sources in protein are all kinds of fish, chicken, pork and nuts.

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Fiber.

The chart says it comes from cellulose, but the researchers didn't specify what it is. There is a big problem in this, so many foreign experts say that the cellulose in it may be similar to paper in essence.

The ketogenic diet of human body usually absorbs dietary fiber beneficial to body and mind in vegetables and whole foods.

There are some problems with the mice used in the study.

In addition to the above reasons, there is another external reason worthy of attention. The mice used in this study are New Zealand obese (NZO) mice, which are very different from ordinary mice.

They are selectively raised, and after genetic modification, their glucose tolerance is impaired, and they are particularly prone to cardiovascular diseases, fatty liver, diabetes and other problems.

Before the formal study began, these mice were pre-diabetic.

There is a deviation in the proportion of diet structure given to rats in the study.

Strictly speaking, what is the proportion of low-carbon ketogenic diet? More than 70% of fat, 20% of protein, and less than 0/0% of carbohydrate/kloc. In this study, the proportion of protein is 13%, which is relatively low, and it is not a low-carbon ketogenic diet in the strict sense.

We must emphasize the importance of protein. Protein is an essential nutrient for human body. It can repair damaged body structures, such as cells, so it should have a place in the low-carbon (ketogenic) diet.

However, there is enough protein in the diet of rats in the standard group, which can ensure adequate physical function and avoid starvation, which is unfair to rats in the low-carbon and high-fat group.

Do not rule out the drive of interest consortia.

I didn't think about this at first, and some experts abroad put it forward. Let's take it as a possible factor.

In recent years, with the popularization of low-carbon (ketogenic) diet, it has brought certain influence to the interests of food industry, large-scale agriculture and enterprises. We have reason to believe that these vested interests are deliberately "manipulating" similar research.

Study 2 Vulnerability

I won't talk about the loopholes in research 2 myself. I found a video screenshot of Dr. Berg specifically targeting this research loophole for everyone to see:

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In short, these mice eat high fat and suffer from diabetes for several reasons:

1, the problem with the mouse itself.

2. It is not really high in fat, but a high-fat diet imagined by researchers.

3. There are many carbohydrates and even saccharin in wheat paste, and the glycemic index is about 1 10.

4, fat is also unhealthy fat, a lot of trans fat.

In fact, it is very simple to get fat on a high-fat diet. Eating unhealthy fats and carbohydrates at the same time, why are you so fat? Because it is high in carbon and fat, it is strange not to be fat.

The relationship between a really healthy ketogenic diet and mice

Dr. Berg also specially proposed another study, using healthy mice and strictly following a healthy ketogenic diet. These mice lost weight, their blood sugar was stable, their metabolic function was improved, and they became energetic.

Compared with mice fed with standard food, mice fed with KD temporarily lost weight, and then stabilized at a lower weight than animals fed with food, in the same pattern as calorie-restricted mice.

Man is not a mouse, and a mouse is not a man.

This must be noted, and I think it is also very important. It is a very good scientific verification method to inspire human beings by doing research on animals, because there are similarities between creatures.

However, there are also differences among various animals, such as mice, whose liver function is inherently poor and their ability to metabolize fat is not as good as that of humans.

Other studies have similar problems.

As mentioned earlier, there are more than 30 similar studies, of which only 5 have reference data, that is, only 14% has practical reference value. So will they have problems, too?

I found several similarities between these studies:

The proportion of nutrients is wrong.

In these studies, rats were given the same diet: 60% lard, 20% sugar and 20% protein, which is the high-fat diet that traditional researchers think.

In fact, the real ketogenic diet is based on low carbon and 20% sugar. It is not a low carbon and high fat diet at all, but a medium carbon and high fat diet.

Fat feeding is unhealthy.

In most studies, they use fat types, such as soybean oil and vegetable oil. Not all oils can lose weight, some research uses soybean oil, hydrogenated vegetable oil, refined coconut oil, etc. There are no virgins or extra virgins. These fats contain a lot of trans fats, which can easily lead to obesity.

Is a low-carbon (ketogenic) diet really bad?

Personally, I used to be a fat man, weighing 170 kg. After four months of low-carbon (ketogenic) diet, I lost 40 Jin, and now I maintain it at 120 Jin. I have ABS, too. I seldom relax and suffer all the way. With these changes, my body has brought great changes to the whole person's mentality.

Netizens who follow my low-carbon (ketogenic) diet also get good news feedback. In addition to losing weight, some people have reversed diabetes and their mentality is getting better and better.

(User message, 65 years old, full of energy because of low carbon)

(User comments, hypoglycemia has improved after low-carbon diet)

In addition, whether at home or abroad, more and more celebrities are trying low-carbon (ketogenic) diets, such as Fan Bingbing and Yi Nengjing mentioned above.

Yi Nengjing loses 50 kilograms per second and Fan Bingbing loses 8 kilograms in 25 days. What mistakes did they make?

Comparison between Yi Nengjing and Fan Bingbing before and after ketogenesis

Foreign stars are: kim kardashian, Rihanna and megan fox, aged 365,438+0.

(Jin Kaidalin came from cosmopolitan before and after ketogenic diet)

As early as four years ago, the Swedish government took the low-carbon (ketogenic) diet as the national "dietary guide" and became the first country to openly challenge the low-fat diet.

Key thin dragon theory

Although there are more than 30 studies on rats eating a high-fat and low-carbon diet, most of them have no detailed experimental data, which is not enough for positive verification, so I found the most sufficient data to analyze with you. Other research on data retention also has many sexual problems.

Of course, using mice to do research, and even using people to do research, found that a high-fat and low-carbon diet is beneficial to animal health.

Also, when we see more positive feedback from ordinary netizens, it is enough to make us confident in a low-carbon (ketogenic) diet.

I also want to emphasize two points about the high-fat diet, which have been emphasized repeatedly. Try to choose healthy fats and good fats, such as coconut oil, butter and olive oil.

In addition, don't eat a high-fat and high-carbon diet, which will have incalculable side effects on the human body.

(After that, did you say too much again? )