Xiao Zan, a 24-year-old vigilant against nasopharyngeal carcinoma, was found to have enlarged cervical lymph nodes during his study in the United States, which was suspected to be nasopharyngeal carcinoma. Because there are very few cases of nasopharyngeal carcinoma in the local area, he is advised to return to China for treatment. Finally, Xiao Zan was diagnosed as nasopharyngeal carcinoma by Professor Xiaoyunjian from the Department of Otolaryngology, Xiangya Hospital of Central South University. Professor Tang Hexiao from the Department of Otolaryngology, Xiangya Hospital of Central South University said that cervical lymphadenopathy is very common. Some patients often go to general surgery first, and send pathological sections after the operation, and find poorly differentiated cancer cells. Only after finding the primary lesion can they find that it is nasopharyngeal carcinoma. Therefore, for patients over 55 years old with cervical lymph node enlargement, especially those with upper cervical lymph nodes, attention should be paid to the examination of nasopharyngeal carcinoma, and the possibility of nasopharyngeal carcinoma should be investigated first through consultation and other examinations. Nasopharyngeal carcinoma (NPC) is a kind of cancer with obvious racial differences, which is common in yellow people and rare in white people. Nasopharyngeal carcinoma is a polygenic disease, which is caused by comprehensive factors such as virus, heredity and environment. The incidence rate is high in South China, such as Guangdong, Hunan, Jiangxi, Fujian and other provinces. In addition, nasopharyngeal carcinoma often has the characteristics of father and daughter, father and son, sister inheritance and so on. All these indicate that the occurrence of nasopharyngeal carcinoma has obvious familial and hereditary characteristics. For patients with cervical lymph node enlargement and suspected nasopharyngeal carcinoma, the following screening should be done first: first, look at the dangerous signals of nasopharyngeal carcinoma, such as nasal congestion and nosebleeds; Hearing loss, tinnitus and diplopia; Headache, facial paralysis or pain, etc. Second, indirect endoscopy of nasopharynx is of great significance for the diagnosis of nasopharyngeal carcinoma and the discovery of early mucosal lesions. The third is nasopharyngeal fibroscopy. Nasopharyngeal fiberscope is soft and enlarged, and can directly bite into suspicious tissue for biopsy under direct vision. This method has been widely used in the screening of nasopharyngeal carcinoma, and has gradually become a common method for the diagnosis of nasopharyngeal diseases. The fourth is the detection of EB virus antibody. Epstein-Barr virus is closely related to nasopharyngeal carcinoma, which covers the whole population. More than 90% of children are positive, but among adults, it gradually decreases with age. Adult EB virus is mostly negative, and the virus titer may increase again when nasopharyngeal carcinoma occurs, so the detection of adult EB virus can be used as a diagnostic reference. The level of EB virus antibody between normal people and nasopharyngeal carcinoma patients is very different. Regular monitoring of antibody level and antibody change trend can predict the occurrence of nasopharyngeal carcinoma, and it is possible to find very early nasopharyngeal carcinoma, and even some patients with no clinical manifestations and no abnormalities under indirect microscope. (Health News)