Dialysis patients often lack water-soluble vitamin B, such as vitamin B 1, vitamin B2, vitamin B6, vitamin C, folic acid, iron, zinc and other trace elements. In particular, the dosage of vitamin B6 should be appropriately increased, and it can be taken orally 10 mg twice a day, because the activity of vitamin B in patients with chronic renal failure is obviously reduced. Due to the reduction of iron absorption in the intestine, patients often suffer from iron deficiency. Ferrous sulfate 300 mg, three times a day, within half an hour after meals. If oral intolerance, dextran deep intramuscular injection or intravenous injection or sucrose iron intravenous injection can be used instead. At the same time, dialysis patients will have decreased blood zinc, and the absorption and maintenance of zinc is closely related to protein. Therefore, for patients with low protein diet, zinc 15-40mg daily can improve cellular immune function, taste and appetite. Active vitamin D3 should also be supplemented, but serum calcium and phosphorus levels must be detected to prevent hypercalcemia. Some dialysis patients have high vitamin content. Excessive vitamin A in the body can stimulate the secretion of parathyroid hormone, cause renal osteodystrophy and lipid metabolism disorder, increase cholesterol and triglyceride, and cause damage to the kidney. Therefore, it should vary from person to person and should not be over-supplemented.