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Brief introduction of Huang Zhongxia: female, chief physician, professor, postgraduate tutor, director of hematology department of Beijing Chaoyang Hospital affiliated to Capital Medical University.
He has been engaged in clinical work in internal medicine for 30 years and has rich clinical experience in hematology. The main research direction is malignant hematological diseases such as multiple myeloma, leukemia and lymphoma, especially the basic and clinical aspects of multiple myeloma. Participated in and undertook many scientific research projects of multiple myeloma, such as National Natural Science Foundation of China, Beijing Natural Science Foundation and ministerial level. Three of them are project leaders. Participated in 3 monographs on multiple myeloma. 1 Editor-in-Chief of popular science books on multiple myeloma. Published more than 30 papers by the first author.
He visited Harvard Medical School and Mayo Hospital.
Expert clinic time: Monday (West Hospital of Beijing Chaoyang Hospital) and Wednesday (Headquarters of Beijing Chaoyang Hospital).
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Auxiliary examination for diagnosis of multiple myeloma;
1. Whole blood cell count (routine blood examination);
2. Biochemical items: including liver function (including albumin and lactate dehydrogenase) and renal function (including creatinine, urea nitrogen, blood calcium, blood potassium and blood uric acid, etc. ) and blood sugar;
3.m protein identification: including serum immunoglobulin quantification, serum protein electrophoresis, serum immunoglobulin light chain quantification, immunofixation electrophoresis and urine (24 hours) immunoglobulin light chain quantification;
4. Serum β2- microglobulin;
5. Bone marrow series examination: ① Bone marrow morphology; ② Pathological biopsy of bone marrow. ③ Immunophenotype of bone marrow cells. ④ Bone marrow gene (fish); ⑤ Chromosome examination;
6. Imaging examination: X-ray, CT or magnetic resonance (MRI) examination of bones (skull, thoracic vertebrae, lumbar vertebrae, thoracic ribs, pelvis, humerus and femur) (when extramedullary invasion or spinal cord compression is suspected), PET-CT examination can be carried out if conditions permit;
7. Examination of blood free light chain: ① Sensitivity is the therapeutic index of MM; ② Amyloidosis and non-secretory type must be checked; ③ Early prediction of disease recurrence; ④ It is highly correlated with the degree of renal injury; ⑤ It can be used as an examination index of minimal residual disease.
Through the above comprehensive examination, enough objective evidence can be provided for clinicians to make a diagnosis of confirming or excluding multiple myeloma. If all the above examinations cannot be completed according to objective conditions, blood picture, bone marrow picture, serum protein electrophoresis, serum immunoelectrophoresis and X-ray examination of bones (skull, thoracic vertebrae, lumbar vertebrae, ribs and pelvis) are necessary examination items, otherwise it is difficult to make a diagnosis. The above results not only provide a basis for clinical diagnosis, but also provide a basis for the classification, clinical staging, treatment and prognosis of myeloma.
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Screening of Multiple Myeloma —— Identification of M Protein in Blood and Urine
Hematuria m protein retention: the nurse took 4 ~ 5 ml of fasting venous blood as a sample.
The retention of urinary M protein is to collect the urine of patients for 24 hours, record the total amount after mixing, and take out a cup (about 10 ml) as a specimen.
Identification and detection time of M protein in Department of Hematology Oncology, West Hospital of Chaoyang Hospital, Beijing: The results are given every Wednesday and Friday.
Department of hematology, West Hospital of Beijing Chaoyang Hospital affiliated to Capital Medical University
Beijing Multiple Myeloma Medical Research Center
China Multiple Myeloma Patients Friends Mutual Assistance Association Beijing Branch