Ligustrum lucidum is also known as alder, holly and wax tree. This wood is green and virtuous, hence the name.
The smell is sweet and enters the liver and kidney meridians.
Efficacy and function: nourishing liver and kidney, improving eyesight and blackening hair, and used for dizziness, tinnitus, soreness of waist and knees, premature gray hair and blurred vision.
Compendium of Materia Medica, the essence of Pharmacopoeia, records that Ligustrum lucidum can tonify the middle energizer, calm the five internal organs, nourish the spirit and eliminate all diseases. Long-term service makes people fat and healthy, intellectual man fit but not old, strong yin, healthy waist and knees, and clear eyes.
Herbal prescription
Treatment of soreness and weakness of waist and knees and premature graying of hair: Mulberry, Ligustrum lucidum and Eclipta prostrata are equally divided. Fry with water into thick juice, add about the same amount of refined honey, and boil into paste. Take 1-2 spoonfuls each time.
Treatment of visual vertigo: Ligustrum lucidum, Lycium barbarum each 15g, Chrysanthemum morifolium 10g, decocted in water. Natural health care
Nourishing liver and improving eyesight: Ligustrum lucidum 250g, Lycium barbarum 100g, liquor 1000ml. Cleaning Fructus Ligustri Lucidi and Fructus Lycii, and soaking in Chinese liquor 15 days.
Nourishing yin and nourishing blood: Ligustrum lucidum 30g, Spatholobus suberectus 15g, Jujube 10, decocted with water instead of tea.
Efficacy, Function and Edible Method of Health-preserving Medicinal Diet of Ligustrum lucidum.
Astringe sweat, astringe and nourish liver and kidney.
Braised pork of Ligustrum lucidum: sea cucumber, lean meat 100g, Schisandra 6g, Ligustrum lucidum, longan 5g, 3 jujubes, 2 slices of ginger and appropriate amount of salt. Soaking Fructus Schisandrae Chinensis, Fructus Ligustri Lucidi and Cortex Cinnamomi Japonici, cleaning Fructus Jujubae, and removing the core; Soaking sea cucumber in warm boiled water and cutting into pieces; Wash lean meat and cut into pieces. Put ginger, pork, sea cucumber, Schisandra chinensis, Ligustrum lucidum, longan pulp and jujube into a pot, add appropriate amount of water, simmer on low heat until the meat is cooked and the soup is dry, and add salt to taste.
Nourish liver and kidney.
Fructus Ligustri Lucidi Mulberry Cake: 200g of flour, 300g of sugar, 20g of Fructus Ligustri Lucidi, 30g of mulberry and Eclipta prostrata, egg 10, yeast and alkaline water. Fry Ligustrum lucidum, Mulberry and Eclipta prostrata in water for about 20 minutes to get juice and break the eggs. Mix flour, yeast, egg liquid, sugar and medicinal juice, knead into dough, add alkaline water after fermentation, knead into cakes, steam in a steamer for about 15 minutes until cooked, and eat as snacks.
Delaying aging and strengthening bones and muscles.
Ligustrum lucidum porridge: 5 grams of Ligustrum lucidum, 0/00 grams of japonica rice/kloc. Washing Fructus Ligustri Lucidi with water, and packing in gauze bag; Wash japonica rice, put it in a pot, put it in a medicine bag of Ligustrum lucidum, and add water to cook porridge.
Ligustrum lucidum is flat and sweet, and enters the liver and kidney meridians. According to Compendium of Materia Medica, Ligustrum lucidum can tonify the middle energizer, soothe the five internal organs, nourish the spirit and eliminate all diseases. Long-term service makes people fat and healthy, intellectual man fit but not old, strong yin, healthy waist and knees, and clear eyes. ? Efficacy, Function and Edible Method of Ligustrum lucidum —— What is Ligustrum lucidum? Ligustrum lucidum is also known as alder, holly and wax tree. This wood is green and virtuous, hence the name. ? Ligustrum lucidum is a small kidney-shaped fruit with shriveled calyx on gray-black skin. Strong body and light body, sweet and bitter taste, liver and kidney yin deficiency is much used. ?
[source]? Is Ligustrum lucidum an evergreen tree of Oleaceae? Ganoderma lucidum? The ripe fruit of Ait ...?
[source]? Location: Zhejiang, Jiangsu, Fujian, Hunan, Sichuan, Guangxi and other provinces. ? [harvesting]? Harvest the fruits when they are ripe in autumn and winter, remove the branches and leaves, steam and dry them. ?
[shape of medicinal materials]? Kidney-shaped or obovate, 0.4- 1 cm long and 0.3-0.4 cm in diameter. The surface is gray-black or purple-black, the base shrinks unevenly, the calyx shrinks, and there are fruit stalk marks. The exocarp is thin, the mesocarp is slightly loose, and the endocarp is yellow-brown, with seeds 1-2? Gold. Thick and light, slightly angry, sweet and slightly bitter. ? It is best to be big, full, gray-black, and solid. ? [concocted]? Sieving the raw materials to remove ash, and picking out the residual fruit stalks; Dry in the sun. Mash it with time. ? Wine Ligustrum lucidum? Clean Ligustrum lucidum 100? Kilogram, with yellow wine 20? Mix kg evenly, slightly stuffy, put it in a steamer or other steaming container, stew it in water or steam it directly until the wine is completely absorbed and the color is dark and moist, and take it out to dry. This product can enhance the function of nourishing liver and kidney after steaming or wine processing. ?
[composition]? The peel contains about 65438 04% oleanolic acid, acetyl oleanolic acid, ursolic acid, mannitol and a lot of glucose. Seeds contain fatty oil. In recent years, ligustilide and oleuropein have been isolated from fruits. ? [Sexual taste, channel tropism]? Sweet and bitter, enter the liver and kidney meridians. ?
[Function]? Nourish liver and kidney, nourish liver and improve eyesight. It can be used for treating yin deficiency of liver and kidney, soreness of waist and knees, deafness with bright eyes, early whitening, insomnia, wet dream night sweats, fluid deficiency and thirst.
[medicinal]? Sweet, bitter and cold. Enter lung, kidney and stomach meridians. ? [medical]? Contains oleanolic acid, mannitol, glucose, etc. ? [pharmacology]? (1) has anticancer activity in vitro. (2) Water immersion can inhibit the growth of transplanted sarcoma in rats; For mouse cervical cancer U- 14? What is the inhibition rate? 30.6~49.2%。 ? (3) Water immersion agent and oleanolic acid have the functions of strengthening the heart, benefiting the body and protecting the liver. (4) Water decoction, mannitol and glucose can slow down the downward movement. ? (5) The decoction can increase leukopenia caused by radiotherapy and chemotherapy. (6) It can inhibit Staphylococcus aureus, Shigella dysenteriae and Escherichia coli. ?
[efficacy]? Detoxification and anticancer, tonifying kidney and nourishing yin, nourishing liver and improving eyesight. ? [medicinal]? (1) detoxification and anticancer, used for cancer and tumor accumulation: liver cancer? Ligustrum lucidum, Scutellaria barbata and Solanum lyratum each 30? G, Rehmannia glutinosa, Carapax Trionycis, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, Rhizoma Sparganii and Rhizoma Curcumae 15? g？ Decoct with water. It is suitable for primary swollen cancer. Esophageal cancer Ligustrum lucidum, Radix Rehmanniae and Radix Rehmanniae each 30? G, Angelica sinensis, Radix Paeoniae Alba, Rhizoma Dioscoreae, Radix Ophiopogonis, Herba Dendrobii, Radix Angelicae Sinensis and Radix Astragali 15? G, persimmon cream, cardamom 6 each? g？ Decocting with water, and mixing with gas to separate powder (Radix Adenophorae and Radix Salviae Miltiorrhizae each 9? 3 mung beans, 3 poria cocos and 3 Fritillaria cirrhosa? G, 1.5 is Radix Curcumae, Fructus Amomi Shell, and the first granule? G, lotus leaf pedicle 2? Gold? A total of research is to open and leave) the same clothes. Suitable for advanced esophageal cancer and cardiac cancer. All of them have achieved positive short-term curative effects. Cervical cancer? Ligustrum lucidum, Scutellaria barbata and Hedyotis diffusa each 30? G, Radix Rehmanniae, Radix Rehmanniae Preparata, Poria, Rhizoma Alismatis, Corni Fructus, Carapax et Plastrum Testudinis, Cortex Lycii, Cortex Moutan, Fructus Gardeniae, Semen Cuscutae, Radix Dipsaci and Rhizoma Dioscoreae 15? g？ Decoct in water, daily 1? Special agent. Knot? Combined with local use of uterine pills, change the dressing daily 1? Time. It can basically cure early cervical cancer. Giant cell tumor of bone: Ligustrum lucidum, Prunella vulgaris, Dendrobium, Radix Dipsaci, Radix Angelicae Sinensis, Radix Rehmanniae Preparata, Rhizoma Drynariae, Rhizoma Sparganii, Rhizoma Curcumae, Radix Astragali, Os Draconis, Concha Ostreae and Rhizoma Cibotii each 30? G, Polygonum Multiflori Radix, Tribulus terrestris, Sanguis Draxonis, Olibanum and Myrrha 15 each? Dick, 90 calf bones? g？ Add bee secret 500? G, boil ointment for oral administration, 30 each time? ML, Japanese service 3? Time. Can be used for comprehensive treatment. ? (2) Deficiency of kidney yin tonifying kidney and benefiting yin: Is the waist and knees sore? Ligustrum lucidum, early lotus grass and so on? Firstly, the morning lotus was mashed, and the paste and Ligustrum lucidum powder were made into Erzhi pills with a weight of 9? Dick, put on a red wine suit. It also treats premature gray hair. ? (3) Nourishing the liver and improving eyesight is used for dizziness: dizziness? Fructus Ligustri Lucidi, Radix Paeoniae Alba and Mother-of-Pearl each 30? g？ Decoct with water. It also treats hyperactivity of liver yang. Central retinitis? Ligustrum lucidum, raspberry, dodder and medlar each 9? g？ Decoct with water. ? [medicine? Quantity]? Decoction: 9~30? Dick. Pills: 4.5~9? Dick. Ointment: 3%30~90? Milliliter. ? [Prescription name]? Ligustrum lucidum? Hot privet? Wine privet? [Usage and dosage]? Fried 10- 15? Dick. ? [storage]? Pack it and put it in a dry place. ? Press:? The processing methods of Ligustrum lucidum include vinegar Ligustrum lucidum, salt Ligustrum lucidum and so on. 1. Ligustrum lucidum black sesame lean broth? Ingredients: lean pork 60? G. Ligustrum lucidum 40? G, black sesame 30? Dick. ? Practice? (1) Clean lean pork and cut into pieces; Wash Ligustrum lucidum and black sesame seeds. ? (2) put all the materials into the pot, add a proper amount of water, bring to a boil with high fire, and simmer with low fire. Hours, seasoning for use. ? Efficacy: tonify kidney and blacken hair, benefit essence and beauty. ? Indications: premature senility and white hair, belonging to deficiency of liver and kidney and deficiency of essence and blood. Symptoms include premature gray hair, fatigue and rough skin, back pain and fatigue, dizziness or hypertension with hyperlipidemia. ? Note: This soup nourishes liver and kidney. The lean meat in the soup is spleen-nourishing, fragrant and sweet. Ligustrum lucidum is sweet and bitter, and its function is to nourish liver and kidney. Shennong's Herbal Classic says that it can "tonify the middle energizer, soothe the nerves of the five internal organs and nourish the spirit ..." It is reported that oleanolic acid contained in it has the functions of strengthening the heart, promoting diuresis and protecting the liver, and can reduce serum cholesterol. Black sesame, also known as sesame oil and hemp seed, is sweet and flat in nature, and has the functions of nourishing liver and kidney, nourishing essence and blood, moistening intestines and bathing. "Depei Materia Medica" says that it can "replenish essence, moisten five internal organs, dredge meridians, smooth skin, treat hematuria and dispel wind." It is one of the commonly used foods for nourishing and caring hair. They are combined into soup, which can tonify kidney and essence, nourish black hair and beauty, but not greasy. It is a good product for reducing fat and bodybuilding black hair. Precautions and taboos: this soup is not suitable for people with cold, fever and constipation. ? 2. Ligustrum lucidum longan soup? Ingredients: pork 60? G, longan meat 20? G. Ligustrum lucidum 60? Dick. ? Practice? (1) Wash pork and cut into pieces. Wash Ligustrum lucidum and round meat. ? (2) Put all the ingredients into the pot, add appropriate amount of water, boil with strong fire, and turn to low heat for 2? Hours, seasoning for use. ? Efficacy: nourishing liver and kidney, benefiting heart and spleen, and blackening hair. ? Indications: Hyperlipidemia, obesity and gray hair belong to liver and kidney deficiency. Symptoms include premature gray hair, alopecia, soreness of waist and knees, nocturia and poor sleep. ? Note: This soup nourishes the liver and kidney, calming the heart and blackening the hair. Soup pork tonifies the spleen and tonifies the deficiency, but not greasy. Ligustrum lucidum is sweet and bitter, and can nourish liver and kidney. Compendium of Materia Medica says that it has the function of "strengthening the waist and knees and turning white hair into tomorrow". Its fruit contains a lot of glucose, oleanolic acid, mannitol, palmitic acid, stearic acid, oleic acid and flaxseed acid, and its peel contains three components. It is reported that Ligustrum lucidum has obvious effects on lowering serum cholesterol and P- lipoprotein, in which the effective rate of lowering total cholesterol is 70.6% and the effective rate of lowering serum P- lipoprotein is 9 1.6%. Longan meat, also known as Longan meat, is sweet in taste, has the functions of strengthening the spleen and nourishing blood, nourishing the heart and calming the nerves, and is rich in vitamins (B, C). It has the functions of preventing skin aging and eliminating pigmentation, and is a good product for skin care. Combine them into soup, nourish liver and kidney, nourish yin and blood, blacken hair and beard, reduce blood fat and prolong life. ?
Caution: This soup is not suitable for people with cold and fever. ?
The smell is sweet and enters the liver and kidney meridians. ?
Efficacy and function: nourishing liver and kidney, improving eyesight and blackening hair, and used for dizziness, tinnitus, soreness of waist and knees, premature gray hair and blurred vision.
Compendium of Materia Medica, the essence of Pharmacopoeia, records that Ligustrum lucidum can tonify the middle energizer, calm the five internal organs, nourish the spirit and eliminate all diseases. Long-term service makes people fat and healthy, intellectual man fit but not old, strong yin, healthy waist and knees, and clear eyes. Herbal prescription? Treatment of soreness and weakness of waist and knees and premature graying of hair: Mulberry, Ligustrum lucidum and Eclipta prostrata are equally divided. Fry with water into thick juice, add about the same amount of refined honey, and boil into paste. Eat 1-2 every time? Spoon. Treating visual vertigo: Ligustrum lucidum and Lycium barbarum? 15? G, chrysanthemum 10? Dick, boil water to drink. Natural health? Nourishing liver and improving eyesight: Ligustrum lucidum 250? Mung beans, medlar? 100? G. Liquor 1000? ML, clean Ligustrum lucidum and Lycium barbarum, and soak them in Chinese liquor 15? Take it every day. Nourishing yin and nourishing blood: Ligustrum lucidum 30? G, Spatholobus suberectus 15? G, jujube 10? First, water decoction instead of tea. ? Ligustrum lucidum-the efficacy, function and eating method of health-preserving medicated diet? Astringe sweat, astringe and nourish liver and kidney. ? Ligustrum lucidum stew: sea cucumber 100, lean meat 65438? G. Schisandra chinensis 6? G, Ligustrum lucidum, longan meat each 5? G. jujube 3? First, ginger 2? Slice and salt. Soaking Fructus Schisandrae Chinensis, Fructus Ligustri Lucidi and Cortex Cinnamomi Japonici, cleaning Fructus Jujubae, and removing the core; Soaking sea cucumber in warm boiled water and cutting into pieces; Wash lean meat and cut into pieces. Put ginger, pork, sea cucumber, Schisandra chinensis, Ligustrum lucidum, longan pulp and jujube into a pot, add appropriate amount of water, simmer on low heat until the meat is cooked and the soup is dry, and add salt to taste. Nourish liver and kidney. ? Ligustrum lucidum mulberry cake: flour 200? G, sugar 300? G. Ligustrum lucidum 20? Grams, mulberries and eclipses? 30? G, egg 10? Yeast, alkaline water, right amount. Fry Ligustrum lucidum, Mulberry and Eclipta prostrata in water for about 20? Take the juice in minutes and break the eggs. Mix flour, yeast, egg liquid, sugar and medicinal juice, knead into dough, add alkaline water after fermentation, knead into cakes, and steam in a steamer for about 15? It will be cooked in a few minutes and can be eaten as a snack. ? Delaying aging and strengthening bones and muscles. ? Ligustrum lucidum porridge: Ligustrum lucidum 5? G, japonica rice 100? Dick. Washing Fructus Ligustri Lucidi with water, and packing in gauze bag; Wash japonica rice, put it in a pot, put it in a medicine bag of Ligustrum lucidum, and add water to cook porridge. Ligustrum lucidum? This product belongs to Oleaceae plant Ligustrum lucidum? Ganoderma lucidum? Ait。 ? Dry ripe fruit. Nature and taste: sweet, bitter and cool. Meridian tropism: Liver and kidney tropism. Indications: nourishing liver and kidney, improving eyesight and blackening hair. Used for dizziness, tinnitus, soreness of waist and knees, premature gray hair and blurred vision. Usage and dosage: 6 ~ 12g. Storage: Store in a dry place. Edit the summary? Directory? 1? Overview? 2? Brief description of drugs? 3? Contraindications to medication? 4? Chemical constituents of traditional Chinese medicine? 5? Pharmacological effect?
Ligustrum lucidum? -? Overview of Ligustrum lucidum?
Ligustrum lucidum is from Compendium of Materia Medica: Ligustrum lucidum, Holly and Ilex cornuta. Privet privet privet is the one now called wax tree; Holly is the one who calls today's green trees frozen; Ilex cornuta is the common name for cat stings. East Renye Fang is called Holly because Ligustrum lucidum is lush and is a foreign body with the same name as Holly. Both are spontaneous and the longest. Its leaves are thick, soft and long, green, its face is green and its back is light; Ligustrum lucidum leaves are four or five inches long and black; The frozen green leaves are slightly round and reddish, which is different from others. It has many flowers and its seeds are full of trees. In winter, scones like to eat them Wood muscle is white and greasy. Today people don't know about Ligustrum lucidum, but it is called wax tree. Ligustrum lucidum evergreen shrubs or trees, up to 25 meters high. The bark is grayish brown. Branches yellow-brown, gray or purplish red, cylindrical, sparsely round or rectangular lenticels. Single leaf opposite; Petiole length 1-3cm, with grooves on it; Leaf blade is leathery, ovate, oblong or elliptic to broadly elliptic, 6-17cm long and 3-8cm wide, with sharp or obtuse tip, rounded base and sometimes wide wedge or cone. Panicle terminal, 8-20 cm long and 8-25 cm wide; Peduncle 3 cm long; Bracts at the base of inflorescence are often the same as leaves, and bracteoles are lanceolate or linear and wither; Flowers sessile or subsessile; Calyx glabrous, long 1.5-2 mm, teeth inconspicuous or nearly truncated; Corolla 4-5 mm long, lobes 2-2.5 mm long, reflexed; The filament length is1.5-3mm, and the anther is oblong, with the length of1-1.5mm.: Style length 1.5-2mm, stigma rod-shaped. The fruit is kidney-shaped or nearly kidney-shaped, with a length of 7- 10mm and a diameter of 4-6 mm. When it matures, it is dark blue and black, red and black, and covered with white powder. Flowering period 5-7? Month, fruit date 7? May of the following year? Month? [ 1]? . ? Ligustrum lucidum? -? Brief description of drugs? Ligustrum lucidum? Drug name: Ligustrum lucidum? Chinese pinyin: nu? Hey? Son.? English name: FRUCTUS? Ligustrum lucidum? Lucidi? Latin animal and plant mineral name: Ligustrum lucidum? Ganoderma lucidum? Ait。 ? Efficacy classification: tonic. ?
Classification of families and genera: Oleaceae. ? Alias: Ligustrum lucidum, Ilex pubescens, Daphnia, Fraxinus mandshurica and Catalpa. Sexual taste: sweet; Bitter; Cold sex. ? Meridian tropism: liver meridian; Kidney meridian. ? Function: tonify liver and kidney; Clearing deficiency and heat; Clean your eyes. ? Indications: dizziness; Pain in the waist and knees; Nocturnal emission; Tinnitus; Hair is gray early, and bone is steaming hot flashes; My eyes are dark and I can't see clearly. ? Administration and dosage: oral: decoction, 6-15g; Or make pills. External use: Apply proper amount to eyes. Clearing deficiency and heat should be used raw, and tonifying liver and kidney should be used cooked. Ecological environment: born at an altitude of 2900m? The sparse forest or dense forest below is also planted in the courtyard or roadside. ? Resource distribution: distributed in Shaanxi, Gansu and the south of the Yangtze River. ? Source: Fruit of Ligustrum lucidum of Oleaceae. Harvest and storage: 4-5 years after transplanting Ligustrum lucidum? Since 2008, the result is 12 per year. When the fruit turns black and has white powder, lay it flat, remove stems, leaves and impurities, and dry it in the sun or hot water. ?
Treatment method:? 1, Ligustrum lucidum: remove impurities, wash and dry. ? 2. Wine Ligustrum lucidum: clean Ligustrum lucidum 100? Gold, add 20 yellow wine? Stir the gold well, put it in a jar or a suitable container, seal it and put it in water? In the pot, stew until the wine is exhausted, and take it out to dry. ? 3, "deserved materia medica": Ligustrum lucidum washed leather, steamed with wine, dried. Stir-fried with light salt water is also acceptable. ?
Ligustrum lucidum? -? Contraindications to medication? 1, diarrhea due to deficiency of spleen and stomach and yang deficiency should not be taken. ? 2, "Materia Medica": When mixed spleen and stomach drugs are used together with red pepper, there is no fear of abdominal pain and diarrhea. Ligustrum lucidum? -? Chemical constituents of traditional Chinese medicine? Ligustrum lucidum? Fruit contains oleanolic acid (oleanolic acid? Acid), acetyl oleanolic acid? Acid), ursolic acid (ursolic acid? Acid), acetoursolic acid acetate? Acid), p-hydroxyphenyl ethanol (p-? Hydroxyphenethyl? Alcohol), 3,4-dihydroxyphenylethanol (3,4-dihydroxyphenylethyl? Alcohol), β -sitosterol (β-sitosterol), mannitol (mannitol), racemic-eriodictyol, dextro-taxifolin, quercetin, ligustilide, 10- hydroxyligustilide (65438. Hydroxyl? Ligustrum lucidum ait), Ligustrum lucidum ait (Ligustrum lucidum ait), Oleuropein,? 10- hydroxy oleuropein (10- hydroxy? P- hydroxyphenylethyl -β-D- glucoside (P-? Hydroxyphenylethyl -β-d- glucoside), 3,4-dihydroxyphenylethyl-β-glucoside (3,4-dihydroxy-? Phenylethyl -β-D- glucoside), methyl -α-D- galactopyranoside (methyl-α-? D- galactopyranoside), eugenol glycoside (acteoside), neoligustilide, and ligustilide (ligustilide? Acid), oleic acid? Acid) and code name GI-3? Cleavage iridoid glycoside. It also contains polysaccharides composed of rhamnose, arabinose, glucose and fucose, with a total amount of 7? Three kinds of phosphatidyl compounds, of which phosphatidyl choline (phosphatidyl choline? Choline) is the highest, accounting for 56.52% of the total? 1.34%。 It also contains potassium, calcium, magnesium, sodium, zinc, iron, manganese, copper, nickel, chromium, silver and so on. 1 1? Among them, copper, iron, zinc, manganese, chromium and nickel are essential trace elements for human body. ? The seeds of Ligustrum lucidum contain Ligustrum lucidum acid (its structure is pentacyclic triterpenoid acid, which has immune activation effect). Ligustrum lucidum contains 8-? Epihoneysuckle glycoside (8-epi). ?
Ligustrum lucidum? -? Pharmacological action Ligustrum lucidum? 1, hypolipidemic and antiatherosclerosis? Feeding Ligustrum lucidum coarse powder (20g/ kg) into the diet can reduce the contents of serum cholesterol and triglyceride in experimental hyperlipidemia rabbits, and reduce the formation of aortic lipid plaque and coronary atherosclerotic plaque. Oleanolic acid in Ligustrum lucidum 30mg/kg? Mixed with drinks and fed to rats, 0.4% oleanolic acid ester suspension 0.5ml? Gavage to rabbits can reduce the blood lipid of hyperlipidemia rats and rabbits. Oleanolic acid 30,60 mg/kg? Add it to feed Japanese quail 8? After several weeks, the contents of serum total cholesterol, lipid peroxide and total cholesterol in arterial wall decreased significantly, and the incidence of atherosclerosis decreased. ? 2. Lowering blood sugar? Oleanolic acid 50, 100 mg/kg? Subcutaneous injection, continuous 7? It can reduce the blood sugar of normal mice, prevent and treat diabetes caused by alloxan, and also resist the blood sugar increase caused by adrenaline or glucose. ? 3. Anti-liver injury? Oleanolic acid 30,50, 100 mg/kg? Subcutaneous injection can inhibit the increase of serum alanine aminotransferase (SGPT) induced by carbon tetrachloride in rats. In rats without carbon tetrachloride treatment, oleanolic acid was 50 mg/kg and 65438 mg/kg? Can subcutaneous injection also make SGPT? Falling. Oleanolic acid 70mg/kg? Subcutaneous injection can alleviate the liver injury caused by carbon tetrachloride. Histologically, the vacuolar degeneration, loose degeneration, hepatocyte necrosis and interlobular interstitial inflammation of hepatocytes were lighter than those of the corresponding control group. Oleanolic acid 2mg/ subcutaneous injection for 6-9 days? Weeks, can prevent and treat liver cirrhosis caused by high-fat food and carbon tetrachloride in rats. Electron microscopic observation showed that subcutaneous injection of oleanolic acid (20mg/ rat) could reduce mitochondrial swelling and endoplasmic reticulum vesicle degeneration of hepatocytes. ? 4. Influence on immune function. Effect on nonspecific immunity? Increase the number of peripheral white blood cells? Ligustrum lucidum can significantly increase the number of white blood cells in peripheral blood, and its effective component is oleanolic acid. The alcohol extract can restore cyclophosphamide (cy)-induced leukopenia in mice. Steamed Ligustrum lucidum 480mg/kg? It has no effect on white blood cells of normal mice, but can correct the decrease of white blood cells caused by prednisolone (25mg/kg, ip). ? Effect on phagocytosis of reticuloendothelial system? The activity of macrophages was observed by the clearance rate of blood foreign bodies. Did you find it? ig？ Steamed Ligustrum lucidum 240mg/kgx5d? Can significantly improve intravenous injection in mice. Carbon clearance index enhanced the activity of reticuloendothelial system; Ligustrum lucidum 480mg/kg, the effect is not obvious. Ligustrum lucidum decoction 12.5g/kgx7d has no obvious effect on the scavenging index, but? 25g/kgx7d？ The phagocytic activity of reticuloendothelial system was obviously inhibited. ? Effect on specific immunity? Effect of Ligustrum lucidum on cellular immune function? Ligustrum lucidum can obviously improve t? Lymphocyte function.
Ligustrum lucidum water extract 0.02ml? In vitro, it significantly enhanced the appropriate amount of PHA and COA? The proliferation of lymphocytes induced by PWM and the local graft-versus-host reaction (GUH) induced by allogeneic (human) lymphocytes in rats may be partly due to the inhibitory T? Through the action of cells. ? Can Ligustrum lucidum polysaccharides (LLPS) enhance the proliferation of mouse spleen lymphocytes stimulated by ConA: 3H-TdR? Consolidated value (Cp? m) 10mg/kg？ Compared with the control group (17959 4508), the medication group (39308. 1.6208) increased by about 120%, P < 0.0 1.50mg/? kg？ Compared with the control group, the drug treatment group (2979 3625) increased by about 70%, P < 0.07. Ligustrum lucidum soup to SRBC? It can promote delayed hypersensitivity. It shows that Ligustrum lucidum can enhance cellular immune function. Oleanolic acid 40mg, 1? The third day? Time, take 1-? 2? In June, it can improve the immune function of tumor patients, phagocytosis of macrophages and rosette formation of blood lymphocytes, which is obviously improved by skin bubble method. Both water extract and alcohol extract of Ligustrum lucidum can induce m? IL- 1？ The effect of water extract is stronger than that of alcohol extract, which reveals that the immune promotion effect of Ligustrum lucidum may be related to the induction of m? -IL- 1？ Related. At the same time, Ligustrum lucidum promotes t? Cell activity is very important for the development of Ts? High activity leads to low immune function, and Ligustrum lucidum may be a good immunomodulatory drug. Effect on humoral immune function? Ligustrum lucidum can enhance humoral immunity.
Ligustrum lucidum decoction ig 12.5~ ~? 25g/kg can increase the weight of thymus and spleen in mice; Large dose can increase the weight of spleen in adult rats. Steamed Ligustrum lucidum? 240 mg/kg, 480 mg/kg× 7? Can God make C57BL? Weight gain of spleen, thymus, abdominal lymph nodes and adrenal gland in mice. Ligustrum lucidum polysaccharide is injected daily 1? Time, a total of 7? 100mg/kg per day? Making LACA? Compared with the control group, the spleen weight of mice increased by about 40%. 50mg/kg？ Compared with the control group, the spleen weight of mice increased by about 30%. Ligustrum lucidum decoction can obviously improve the activity of serum hemolysin antibody in mice, and also increase the content of serum IgG in normal mice, antagonizing Cy? Immunosuppressive effect; Steamed Ligustrum lucidum can obviously resist the immunosuppressive effect of prednisolone, increase the serum IgG of mice, and make prednisolone immunosuppressed the IgG of mice. The increase of content can obviously prompt mice to remember the antibody activity of albumin; Effect of Ligustrum lucidum polysaccharide on Cy50mg/kgip? The inhibitory effect on lymphocyte proliferation of tumor-bearing mice (S 180) was low, and the polysaccharide of Ligustrum lucidum was obviously resistant to Cy? Immunosuppressive effect. ? Have an inhibitory effect on allergic reactions? Ligustrum lucidum decoction12.5,25g/kgig? The mice were 7 days old; The same dose of 5dig? In rats, different doses of Ligustrum lucidum showed obvious inhibitory effect on passive skin allergic reaction (PCA) in mice or rats. Ligustrum lucidum decoction can reduce the degranulation percentage of mast cells in rat skull membrane and resist the increase of capillary permeability of rat skin caused by histamine. Can administration before antigen challenge inhibit DNCB? Contact dermatitis in mice; Ligustrum lucidum 25g/kg? Administration after antigen stimulation can also significantly inhibit it? DNCB？ The process of skin contact in mice; Reduce active and passive arthritis in rats? Reaction; Ligustrum lucidum 20g/kg? Significantly reduced serum total complement in guinea pigs. It shows that Ligustrum lucidum has obvious inhibitory effect on type ⅰ, ⅱ and ⅳ allergic reactions. ? 5. Anti-inflammatory effect? Ligustrum lucidum 12.5g/kg, 25g/kg? Ig daily for 5 consecutive days? It has obvious inhibitory effects on mouse auricle swelling caused by xylene, increase of abdominal capillary permeability caused by acetic acid, and swelling of rat foot pad caused by carrageenan, egg white and formaldehyde. Ligustrum lucidum 20g/kg×3? Can daily ig significantly reduce inflammatory tissue in rats? PGE？ The release amount of; Ligustrum lucidum 20g? /kg×7？ Tianneng can inhibit the proliferation of cotton ball granulation tissue in rats, accompanied by the increase of adrenal gland weight. Its anti-inflammatory mechanism may involve the following aspects: ①? Activating the pituitary-adrenal cortex system and promoting the release of cortical hormones; ? ②? Inhibit PGE? Synthesize or release. In addition, Ligustrum lucidum can reduce the serum complement activity of guinea pigs and resist the increase of skin capillary permeability caused by histamine, so the anti-inflammatory mechanism of Ligustrum lucidum may also include the above effects. ? 6. Anti-cancer and anti-mutation? Effect of oleanolic acid on sarcoma-180 in mice? It has anti-tumor effect. Ligustrum lucidum decoction12.5,25g/kg? Oral, oleanolic acid 50, 100 mg/kg? Subcutaneous injection can obviously inhibit the increase of micronucleus rate in bone marrow of mice caused by cyclophosphamide and urethane. ? 7. What is the role of endocrine system? Studies have shown that there are both estrogen-like substances and androgen-like substances in Ligustrum lucidum. By radioimmunoassay, Ligustrum lucidum contains 428.438 0pg/g of testosterone and 65438 039.02pg/g of estradiol, which proves that Ligustrum lucidum has both testosterone-like and estradiol-like hormone analogues, that is, the same drug has two-way regulation effect. Ligustrum lucidum and other traditional Chinese medicines have estrogen-like effects on vaginal mucosa of weak mice. The number of large follicles in the ovaries of rabbits in the medication group increased significantly, and estrogen increased. ? 8. Effect on hematopoietic system? Ligustrum lucidum can promote erythropoiesis. Using diffusion box plasma coagulation method, Ligustrum lucidum can promote CFU-E Grow up. CFU-E/5×l4？ 128.6 is 1 1.4 (8), CFU? E/ femur is 62040 5450 (8), CFU-E in femur? Compared with NS? Group a was significantly higher, while CFU-D But it has been significantly reduced. Morphological analysis of bone marrow cells in mice after administration showed that the percentage of erythroid cells in Ligustrum lucidum group was 47.3 2.99 (6) higher than that in NS 37.3 2.86 (6) group, and the percentage of granulocyte cells was 37.6? 3.96 (6) is greater than NS? In group A, 46.6 6.26 (6) decreased, and the grain-to-red ratio changed accordingly. ? 9. What are the protective effects of cyclophosphamide and urethane on chromosome damage? Micronucleus test proved that the water decoction of Ligustrum lucidum was pol2.5g/? Kg 25.0 g/(kg d) × 6, oleanolic acid ih50mg/kg,100 mg/(kg d) × 7? For cyclophosphamide IP 50mg/(kg d) × 2 and urethane 500mg/(kg d) × 4, IP? It has protective effect on chromosome damage in mice and can reduce its micronucleus rate. ? 10, HpD prevention? Photochlorination? Can Ligustrum lucidum resist HpD? Photooxidation of HpD can be significantly reduced by in vivo application. Photosensitive reaction to mouse skin. Ligustrum lucidum 60mg? Crude drug /ml, can significantly reduce HpD5ug/ml? Combined lighting 10min? The inhibition rate of erythrocyte malondialdehyde was 57.7%, which obviously inhibited the activity of erythrocyte membrane acetylcholinesterase, and the inhibition rates were 49.0%, 65,438+0.20 mg/ml respectively? At that time, the antagonistic rate was 53.3%, the mouse IPHPD was 20 mg/kg, and the exposure time was 4? H, Ligustrum lucidum 20g? Crude drug /kg, ip 1? Second, the photosensitive response of the ear is obviously reduced. Ligustrum lucidum 1O2? The efficiency was 3.5× 10-4 lower than that of the control group? Time magazine. ? 1 1, other functions? Ligustrum lucidum also has cardiovascular system functions such as strengthening the heart, dilating coronary blood vessels and dilating peripheral blood vessels. Diuretic, antitussive, laxative and antibacterial effects. Oleanolic acid has a certain cardiotonic diuretic effect; Mannitol has a slowing effect; It also contains a lot of glucose; These may be related to its strong effect. Ligustrum lucidum? -? Pharmacology (Toxicology) Ligustrum lucidum has little toxicity to animals. Eat 75g fresh and ripe fruit without poisoning. ? Ligustrum lucidum? -? Common prescriptions? Ligustrum lucidum? 1, Ligustrum lucidum Dan (Fushou Jing Fang): Treating yin deficiency of liver and kidney, strengthening bones and muscles, blackening hair and stopping bleeding. Soak Ligustrum lucidum and Platycodon grandiflorum leaves in wine for a day and night, rub the skin with a coarse cloth bag, dry in the sun, mash the juice and boil it into pills, and send 100 pills every night. ? 2. Ligustrum lucidum Ointment ("Diagnosis and Treatment of Dermatology of Traditional Chinese Medicine"): Treating white hair, alopecia areata and alopecia totalis. Ligustrum lucidum 500? Dick, the big winner 250? Dick. Boil the cream. 20 each? ML, warm water, 2-3 days? Time. ? 3. Fructus Ligustri Lucidi Mulberry Decoction (Prescription of China Medicinal Diet): Treat liver and kidney dizziness and premature gray hair. Ligustrum lucidum and Polygonum multiflorum Thunb 12? G, mulberry 15? g，eclipse ta 10？ Dick. Decoct with water. ? 4, Ligustrum lucidum powder: treatment of complexion such as dirt, long-term coal black, dry and dull, or the size of dark spots is the same as the skin. Ligustrum lucidum (water flies to the salt sand, fried thoroughly, spread the fire) and aster are divided equally. To end it. 2 per serving? Money, the next day? Take the old wine ?
?