COVID-19 culture and animal infection experiments should be carried out in biosafety level III and above laboratories. The operation of uncultured infectious substances should be carried out in biosafety level 2 and above laboratories, and biosafety level 3 laboratories should at least do personal protection. The operation of inactivated materials should be carried out in biosafety level 2 and above laboratories. Operations that do not involve infectious substances can be carried out in biosafety laboratories.

Viruses can be inactivated by biological, physical and chemical methods. Biological inactivation means that the virus that invades the human body passes through the immune cells of the human body, and then combines with the corresponding parts of the virus or produces corresponding antibodies, thus being killed by phagocytes. Physical inactivation refers to the early destruction of virus structure by means of high temperature and ultraviolet rays, so as to inactivate it. For example, the pressure cooker uses the principle that the virus protein can't withstand high temperature to destroy the virus protein, so as to achieve the purpose of fire fighting. Chemical inactivation refers to the use of disinfectants, alcohol and other chemicals to inactivate the virus. For example, chloroform destroys the lipid structure of the virus, thus inactivating the virus. There are many ways to inactivate viruses, and the appropriate method can be selected according to different environments.