A Chinese medicinal composition, Compound Danshen Liquor, and its preparation method are provided. Chopping Saviae Miltiorrhizae Radix, Fructus Crataegi and Cortex Moutan, soaking in Chinese liquor, and filtering to obtain medicinal liquor stock solution; Boiling the residue with water, filtering to obtain water extract, adding the water extract into the original liquor of medicinal liquor, and adding edible acetic acid to obtain the finished product. This product can improve circulation, improve hypoxia tolerance, improve heart function, treat heart failure, reduce paroxysmal atrial fibrillation, frequent premature beats and other arrhythmia attacks, and increase the heart rate of patients with sinus bradycardia, and can be used to treat cardiovascular diseases. It can also promote the repair and regeneration of tissues and promote the repair and healing of fractures. It can improve the physiological function of the liver, promote the retraction and softening of the liver and spleen, and has the functions of detoxification, antibiosis, analgesia and blood pressure reduction.
The goal of atrial fibrillation treatment is to control the ventricular rate satisfactorily, restore sinus rhythm and prevent its recurrence, in addition to preventing thromboembolism complications. There are two kinds of antiarrhythmic drugs used in atrial fibrillation: 1 antiarrhythmic drugs used for cardioversion of atrial fibrillation, recovery of sinus rhythm and prevention of recurrence, including Class IA (such as quinidine), Class ic (such as propafenone and Morexizine) and Class III (amiodarone and Sotalol). It mainly acts on atrium, prolonging atrial refractory period or slowing atrial conduction. 2 drugs to slow down the ventricular rate, including beta blockers and non-dihydropyridine calcium antagonists (verapamil and diltiazem? ) and digitalis drugs. They act on atrioventricular node, prolong refractory period of atrioventricular node and increase concealed conduction. In the past, some clinicians misunderstood the drugs that slow down the ventricular rate as having the function of converting atrial fibrillation into sinus rhythm or preventing the recurrence of atrial fibrillation, such as digitalis (lanatoside C, digoxin), non-dihydropyridine (verapamil, diltiazem? ) and beta blockers. Some randomized, double-blind studies show that compared with placebo, there is no significant difference between the effective rate and time of cardioversion from the beginning of taking lanatoside C. Quinidine has been widely used in cardioversion of persistent atrial fibrillation and prevention of atrial fibrillation recurrence in China, but clinical research shows that quinidine can effectively treat atrial fibrillation, but it may increase the mortality.
Treatment of various types of atrial fibrillation
1. Paroxysmal atrial fibrillation: When atrial fibrillation attacks, you can choose drugs to slow down the ventricular rate or cardioversion drugs. For frequent authors, cardioversion drugs that act on atrium should be used during the interval of attack, rather than drugs that slow down ventricular rate. For simple atrial fibrillation and non-coronary atrial fibrillation with hypertension or left ventricular hypertrophy, propafenone or morexizine is the first choice, if it fails, sotalol is used, and amiodarone is used in the later stage. Coronary heart disease and atrial fibrillation after myocardial infarction do not need IC drugs. If the patient is young and has good cardiac function, sotalol can be used; Old age, poor heart function, choose amiodarone; Amiodarone is suitable for paroxysmal atrial fibrillation of chronic congestive heart failure.
2. Persistent atrial fibrillation: Treatment strategies include: 1) cardioversion and long-term use of antiarrhythmic drugs to prevent recurrence. 2) Slow down ventricular rate and anticoagulation. If the strategy 1 is selected, it should be considered as a cardioversion drug for atrial fibrillation, and the principle of drug selection is the same as that of paroxysmal atrial fibrillation; If you choose strategy two, you should choose drugs to slow down the ventricular rate.
3. Permanent atrial fibrillation: it is an atrial fibrillation that cannot restore sinus rhythm. Treatment should choose drugs and anticoagulants to reduce ventricular rate.
Digitalis drugs (1) can slow down the ventricular rate and have a positive inotropic effect, which can be used for patients with atrial fibrillation and cardiac insufficiency. Digitalis drugs can indirectly act on the atrioventricular node by exciting vagus nerve, prolong its refractory period, increase recessive conduction, and thus slow down the ventricular rate, so digitalis drugs can satisfactorily control the ventricular rate of atrial fibrillation during sleep and rest. However, in critical emergencies such as cor pulmonale, asthma, acute left heart failure and perioperative period, digitalis drugs have limited efficacy when sympathetic nerve activity is dominant or sympathetic nerve is excited.
(2) Beta blockers can antagonize sympathetic nerve activity. Non-dihydropyridine calcium antagonists can slow down atrioventricular conduction and ventricular rate by blocking calcium channels, which can effectively control ventricular rate not only in sleep or resting state, but also in atrial fibrillation during exercise. For the above-mentioned critical emergencies, intravenous diltiazem can be used when pilocarpine C and other drugs are ineffective. . In addition, digitalis, non-dihydropyridine calcium antagonists and beta blockers are prohibited for atrial fibrillation complicated with preexcitation syndrome. Drugs (such as intravenous procainamide, propafenone or amiodarone) should be used to prolong the refractory period of atrioventricular bypass.
Ibuti 1ide is also a new class ⅲ antiarrhythmic drug, which prolongs the effective refractory period of atrium and ventricle and has little effect on the conduction of normal heart tissue. Ibuti 1ide is effective for the conversion of atrial fibrillation in the near future. Studies have shown that the efficacy of Ibuti 1ide in cardioversion of atrial fibrillation is better than procainamide.
/jbzt/neike/xnke/xlsc/kssc/xfcd/20040706 160242699 1 . htm
Atrial fibrillation, full name of atrial fibrillation, is one of the common arrhythmia. There are many possible reasons. Atrial fibrillation mostly occurs in people with obvious cardiac diseases, and is common in rheumatic heart disease (especially mitral valve disease), coronary heart disease, hypertensive heart disease, hyperthyroidism heart disease and chronic constrictive pericarditis. Sometimes improper use of some western medicines can also cause transient atrial fibrillation, and some normal people will also have atrial fibrillation due to excessive fatigue.
Patients with mild atrial fibrillation generally have no obvious symptoms, and most of the symptoms are related to the heart rate. Palpitation is a common symptom of patients, and the ventricular rhythm is often faster in paroxysmal or first attack. Palpitation, chest tightness, panic symptoms are obvious, and occasionally polyuria. Atrial fibrillation mostly occurs in patients with organic heart disease, which is the cause of heart failure. Most patients with chronic rheumatic heart disease suffer from persistent atrial fibrillation, and their cardiac function and labor tolerance are obviously reduced. In patients with high mitral stenosis, atrial fibrillation can be complicated with pulmonary edema when the heart rate increases. In the first few minutes of atrial fibrillation, sometimes the stroke volume suddenly decreases, and the vascular compensation response does not work, leading to cerebral ischemia and syncope. When atrial fibrillation is terminated, occasional fainting may occur due to cardiac arrest.
It is worth noting that atrial fibrillation leads to long-term atrial congestion, especially in patients with mitral stenosis and rapid ventricular rate, which easily leads to atrial thrombosis. Partial thrombus shedding can cause systemic arterial embolism, especially cerebral embolism.
Traditional Chinese medicine treatment of atrial fibrillation is mainly based on the overall situation, listening, asking and inquiring. Generally speaking, deficiency of spleen and stomach qi will damage spleen yang, destroy traffic, weaken ancestors' qi, lack of heart qi, poor heart pulse and abnormal circulation, leading to palpitation. Treatment should be warming yang and harmonizing middle energizer, benefiting qi and regulating pulse.
Fuzi10g (fried first), Ginseng Radix Rubri10g, Zingiberis Rhizoma 5g, fried atractylodes15g, Radix Glycyrrhizae Preparata10g, Ramulus Cinnamomi10g, 7 Chinese dates, and Salvia Miltiorrhiza Radix15g. Decoct with water. Can be used in combination with 7- 15 dose. If effective, you can take it intermittently for 2 months.
Of course, not everyone is suitable for using the above traditional Chinese medicine. Because of personal circumstances, the best way is to find an experienced Chinese medicine expert.
Modern atrial fibrillation is divided into paroxysmal atrial fibrillation, persistent atrial fibrillation and permanent atrial fibrillation. The goal of atrial fibrillation treatment is to control the ventricular rate satisfactorily, restore sinus rhythm and prevent its recurrence, in addition to preventing thromboembolism complications. There are two kinds of antiarrhythmic drugs used in atrial fibrillation: 1 antiarrhythmic drugs used for cardioversion of atrial fibrillation, recovery of sinus rhythm and prevention of recurrence, including Class IA (such as quinidine), Class ic (such as propafenone and Morexizine) and Class III (amiodarone and Sotalol). It mainly acts on atrium, prolonging atrial refractory period or slowing atrial conduction. 2 drugs to slow down the ventricular rate, including beta blockers and non-dihydropyridine calcium antagonists (verapamil and diltiazem? ) and digitalis drugs. They act on atrioventricular node, prolong refractory period of atrioventricular node and increase concealed conduction. In the past, some clinicians misunderstood the drugs that slow down the ventricular rate as having the function of converting atrial fibrillation into sinus rhythm or preventing the recurrence of atrial fibrillation, such as digitalis (lanatoside C, digoxin), non-dihydropyridine (verapamil, diltiazem? ) and beta blockers. Some randomized, double-blind studies show that compared with placebo, there is no significant difference between the effective rate and time of cardioversion from the beginning of taking lanatoside C. Quinidine has been widely used in cardioversion of persistent atrial fibrillation and prevention of atrial fibrillation recurrence in China, but clinical research shows that quinidine can effectively treat atrial fibrillation, but it may increase the mortality.
Treatment of various types of atrial fibrillation
1. Paroxysmal atrial fibrillation: When atrial fibrillation attacks, you can choose drugs to slow down the ventricular rate or cardioversion drugs. For frequent authors, cardioversion drugs that act on atrium should be used during the interval of attack, rather than drugs that slow down ventricular rate. For simple atrial fibrillation and non-coronary atrial fibrillation with hypertension or left ventricular hypertrophy, propafenone or morexizine is the first choice, if it fails, sotalol is used, and amiodarone is used in the later stage. Coronary heart disease and atrial fibrillation after myocardial infarction do not need IC drugs. If the patient is young and has good cardiac function, sotalol can be used; Old age, poor heart function, choose amiodarone; Amiodarone is suitable for paroxysmal atrial fibrillation of chronic congestive heart failure.
2. Persistent atrial fibrillation: Treatment strategies include: 1) cardioversion and long-term use of antiarrhythmic drugs to prevent recurrence. 2) Slow down ventricular rate and anticoagulation. If the strategy 1 is selected, it should be considered as a cardioversion drug for atrial fibrillation, and the principle of drug selection is the same as that of paroxysmal atrial fibrillation; If you choose strategy two, you should choose drugs to slow down the ventricular rate.
3. Permanent atrial fibrillation: it is an atrial fibrillation that cannot restore sinus rhythm. Treatment should choose drugs and anticoagulants to reduce ventricular rate.
Digitalis drugs (1) can slow down the ventricular rate and have a positive inotropic effect, which can be used for patients with atrial fibrillation and cardiac insufficiency. Digitalis drugs can indirectly act on the atrioventricular node by exciting vagus nerve, prolong its refractory period, increase recessive conduction, and thus slow down the ventricular rate, so digitalis drugs can satisfactorily control the ventricular rate of atrial fibrillation during sleep and rest. However, in critical emergencies such as cor pulmonale, asthma, acute left heart failure and perioperative period, digitalis drugs have limited efficacy when sympathetic nerve activity is dominant or sympathetic nerve is excited.
(2) Beta blockers can antagonize sympathetic nerve activity. Non-dihydropyridine calcium antagonists can slow down atrioventricular conduction and ventricular rate by blocking calcium channels, which can effectively control ventricular rate not only in sleep or resting state, but also in atrial fibrillation during exercise. For the above-mentioned critical emergencies, intravenous diltiazem can be used when pilocarpine C and other drugs are ineffective. . In addition, digitalis, non-dihydropyridine calcium antagonists and beta blockers are prohibited for atrial fibrillation complicated with preexcitation syndrome. Drugs (such as intravenous procainamide, propafenone or amiodarone) should be used to prolong the refractory period of atrioventricular bypass.
Ibuti 1ide is also a new class ⅲ antiarrhythmic drug, which prolongs the effective refractory period of atrium and ventricle and has little effect on the conduction of normal heart tissue. Ibuti 1ide is effective for the conversion of atrial fibrillation in the near future. Studies have shown that the efficacy of Ibuti 1ide in cardioversion of atrial fibrillation is better than procainamide.
/jbzt/neike/xnke/xlsc/kssc/xfcd/20040706 160242699 1 . htm
Atrial fibrillation, full name of atrial fibrillation, is one of the common arrhythmia. There are many possible reasons. Atrial fibrillation mostly occurs in people with obvious cardiac diseases, and is common in rheumatic heart disease (especially mitral valve disease), coronary heart disease, hypertensive heart disease, hyperthyroidism heart disease and chronic constrictive pericarditis. Sometimes improper use of some western medicines can also cause transient atrial fibrillation, and some normal people will also have atrial fibrillation due to excessive fatigue.
Patients with mild atrial fibrillation generally have no obvious symptoms, and most of the symptoms are related to the heart rate. Palpitation is a common symptom of patients, and the ventricular rhythm is often faster in paroxysmal or first attack. Palpitation, chest tightness, panic symptoms are obvious, and occasionally polyuria. Atrial fibrillation mostly occurs in patients with organic heart disease, which is the cause of heart failure. Most patients with chronic rheumatic heart disease suffer from persistent atrial fibrillation, and their cardiac function and labor tolerance are obviously reduced. In patients with high mitral stenosis, atrial fibrillation can be complicated with pulmonary edema when the heart rate increases. In the first few minutes of atrial fibrillation, sometimes the stroke volume suddenly decreases, and the vascular compensation response does not work, leading to cerebral ischemia and syncope. When atrial fibrillation is terminated, occasional fainting may occur due to cardiac arrest.
It is worth noting that atrial fibrillation leads to long-term atrial congestion, especially in patients with mitral stenosis and rapid ventricular rate, which easily leads to atrial thrombosis. Partial thrombus shedding can cause systemic arterial embolism, especially cerebral embolism.
Traditional Chinese medicine treatment of atrial fibrillation is mainly based on the overall situation, listening, asking and inquiring. Generally speaking, deficiency of spleen and stomach qi will damage spleen yang, destroy traffic, weaken ancestors' qi, lack of heart qi, poor heart pulse and abnormal circulation, leading to palpitation. Treatment should be warming yang and harmonizing middle energizer, benefiting qi and regulating pulse.
Fuzi10g (fried first), Ginseng Radix Rubri10g, Zingiberis Rhizoma 5g, fried atractylodes15g, Radix Glycyrrhizae Preparata10g, Ramulus Cinnamomi10g, 7 Chinese dates, and Salvia Miltiorrhiza Radix15g. Decoct with water. Can be used in combination with 7- 15 dose. If effective, you can take it intermittently for 2 months.
Of course, not everyone is suitable for using the above traditional Chinese medicine. Because of personal circumstances, the best way is to find an experienced Chinese medicine expert.