(1) Pre-Qin period: Bian Que was the most famous doctor in the Warring States period. Later generations regarded him as a "master of pulse science". He used four diagnoses: seeing, hearing, asking and cutting, and diagnosed the condition from the pulse condition. Pulse-taking is Bian Que's main achievement. Four diagnostic methods have become the traditional diagnostic methods of Chinese medicine, which have been used by Chinese medicine for more than two thousand years.

(2) Han Dynasty: ① Huangdi Neijing, published in the Warring States and compiled by the Western Han Dynasty, was an important medical document in early China. It laid the theoretical foundation of traditional Chinese medicine. (2) Shennong's Classic of Materia Medica in the Eastern Han Dynasty is the first complete pharmacological work in China. ③ Hua Tuo, a famous doctor at the end of the Eastern Han Dynasty, was good at surgery and was known as the "imperial doctor". Mafeisan was invented earlier than the west 1600 years ago. ④ Zhang Zhongjing, a famous doctor at the end of the Eastern Han Dynasty, was called a "medical sage", and his masterpiece Treatise on Febrile Diseases was an important classic of Chinese medicine in later generations.

(3) Sui and Tang Dynasties: (1) Qian Jin Fang, written by Sun Simiao, an outstanding physician in the Tang Dynasty, comprehensively summarized the medical achievements of all previous dynasties and at that time, and had many original opinions, which occupied an important position in the history of traditional Chinese medicine. ② The Four Medical Codes compiled by Yuan Dan Gongbu, a famous Tibetan doctor, have important influence at home and abroad. (3) Tang Materia Medica, compiled and revised in Tang Gaozong period, is the earliest compendium in the world and promulgated by the state.

(4) Ming and Qing Dynasties: In the Ming Dynasty, Li Shizhen's Compendium of Materia Medica recorded 1800 kinds of drugs and 10000 kinds of prescriptions, which comprehensively summarized China's medicine before16th century, and was known as the "Grand Ceremony of Oriental Medicine". Li Shizhen attaches great importance to field investigation and experimental observation, and pays attention to the application of comparative methods, which has high scientific value in understanding and summarizing drugs. The classification of drugs in Compendium of Materia Medica embodies the viewpoint that biological evolution is from low level to high level. Li Shizhen also put forward the view that "birds are born in forests, so their feathers are like leaves", which reflected his new understanding of animals' adaptation to the environment, related variation and genetic characteristics.