Generally speaking, feeling cold after drinking belongs to the normal reflection and reaction of human body. Because people drink too much, they will have negative nitrogen balance, glycogen will decompose quickly and be absorbed and synthesized less. Therefore, when glycogen is consumed in large quantities, it will cause a transient hypoglycemia reaction. When the blood sugar is lower than 3.9mmol/L, there will be an increase in heat production, and then there will be clinical situations of chills and chills.

Feeling cold after drinking is due to the release of inflammatory factors in the body. After drinking too much, a large amount of acetaldehyde will release inflammatory mediators in the body, such as leukotrienes, bradykinin, prostacyclin and other substances, which will stimulate capillaries and surrounding nerve centers and make them feel cold. People who drink too much will have serious nausea and vomiting, which will make the gastrointestinal tract secrete gastric acid quickly and lose a lot of heat. After drinking, they will feel chilly.